フォロー
Yuki Toyama
Yuki Toyama
RIKEN Center for Biosystems Dynamics Research
確認したメール アドレス: riken.jp
タイトル
引用先
引用先
Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase
TH Kim, BJ Payliss, ML Nosella, ITW Lee, Y Toyama, JD Forman-Kay, ...
Proceedings of the National Academy of Sciences 118 (23), e2104897118, 2021
542021
Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel
H Kano, Y Toyama, S Imai, Y Iwahashi, Y Mase, M Yokogawa, M Osawa, ...
Nature communications 10 (1), 2008, 2019
512019
Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses
Y Toyama, H Kano, Y Mase, M Yokogawa, M Osawa, I Shimada
Nature communications 8 (1), 1-15, 2017
342017
Oligomeric assembly regulating mitochondrial HtrA2 function as examined by methyl-TROSY NMR
Y Toyama, RW Harkness, TYT Lee, JT Maynes, LE Kay
Proceedings of the National Academy of Sciences 118 (11), e2025022118, 2021
322021
NMR method for characterizing microsecond-to-millisecond chemical exchanges utilizing differential multiple-quantum relaxation in high molecular weight proteins
Y Toyama, M Osawa, M Yokogawa, I Shimada
Journal of the American Chemical Society 138 (7), 2302-2311, 2016
322016
Mapping the per-residue surface electrostatic potential of CAPRIN1 along its phase-separation trajectory
Y Toyama, AK Rangadurai, JD Forman-Kay, LE Kay
Proceedings of the National Academy of Sciences 119 (36), e2210492119, 2022
232022
Conformational landscape alternations promote oncogenic activities of Ras-related C3 botulinum toxin substrate 1 as revealed by NMR
Y Toyama, K Kontani, T Katada, I Shimada
Science advances 5 (3), eaav8945, 2019
232019
Structural basis for the ethanol action on G-protein–activated inwardly rectifying potassium channel 1 revealed by NMR spectroscopy
Y Toyama, H Kano, Y Mase, M Yokogawa, M Osawa, I Shimada
Proceedings of the National Academy of Sciences 115 (15), 3858-3863, 2018
162018
The A39G FF domain folds on a volcano-shaped free energy surface via separate pathways
VP Tiwari, Y Toyama, D De, LE Kay, P Vallurupalli
Proceedings of the National Academy of Sciences 118 (46), e2115113118, 2021
142021
Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP
RW Harkness, Y Toyama, ZA Ripstein, H Zhao, AIM Sever, Q Luan, ...
Proceedings of the National Academy of Sciences 118 (32), e2109732118, 2021
142021
Dissecting the role of interprotomer cooperativity in the activation of oligomeric high-temperature requirement A2 protein
Y Toyama, RW Harkness, LE Kay
Proceedings of the National Academy of Sciences 118 (35), e2111257118, 2021
122021
Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties
Y Toyama, AK Rangadurai, JD Forman-Kay, LE Kay
Journal of Biological Chemistry 299 (1), 2023
92023
Less is more: A simple methyl-TROSY based pulse scheme offers improved sensitivity in applications to high molecular weight complexes
N Bolik-Coulon, AIM Sever, RW Harkness, JM Aramini, Y Toyama, ...
Journal of Magnetic Resonance 346, 107326, 2023
92023
Measurement of 1Hα transverse relaxation rates in proteins: application to solvent PREs
Y Toyama, AK Rangadurai, LE Kay
Journal of Biomolecular NMR 76 (4), 137-152, 2022
92022
Probing allosteric interactions in homo-oligomeric molecular machines using solution NMR spectroscopy
Y Toyama, LE Kay
Proceedings of the National Academy of Sciences 118 (50), e2116325118, 2021
92021
Structural basis of protein substrate processing by human mitochondrial high-temperature requirement A2 protease
Y Toyama, RW Harkness, LE Kay
Proceedings of the National Academy of Sciences 119 (17), e2203172119, 2022
72022
Analyzing multi-step ligand binding reactions for oligomeric proteins by NMR: Theoretical and computational considerations
RW Harkness, Y Toyama, LE Kay
Journal of Magnetic Resonance 318, 106802, 2020
62020
Decreased conformational stability in the oncogenic N92I mutant of Ras-related C3 botulinum toxin substrate 1
Y Toyama, K Kontani, T Katada, I Shimada
Science Advances 5 (8), eaax1595, 2019
52019
Frequency selective coherence transfer NMR spectroscopy to study the structural dynamics of high molecular weight proteins
Y Toyama, I Shimada
Journal of Magnetic Resonance 304, 62-77, 2019
52019
Practical considerations for the measurement of near-surface electrostatics based on solvent paramagnetic relaxation enhancements
AK Rangadurai, Y Toyama, LE Kay
Journal of Magnetic Resonance 349, 107400, 2023
32023
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