| New insights into the mechanism of action of acetaminophen: its clinical pharmacologic characteristics reflect its inhibition of the two prostaglandin H 2 synthases DM Aronoff, JA Oates, O Boutaud Taylor & Francis, 2006 | 320 | 2006 |
| Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H2 synthases O Boutaud, DM Aronoff, JH Richardson, LJ Marnett, JA Oates Proceedings of the National Academy of sciences 99 (10), 7130-7135, 2002 | 307 | 2002 |
| Tobacco smoking induces cardiovascular mitochondrial oxidative stress, promotes endothelial dysfunction, and enhances hypertension S Dikalov, H Itani, B Richmond, L Arslanbaeva, A Vergeade, ... American Journal of Physiology-Heart and Circulatory Physiology 316 (3 …, 2019 | 198 | 2019 |
| Inherited human cPLA2α deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction DH Adler, JD Cogan, JA Phillips, N Schnetz-Boutaud, GL Milne, T Iverson, ... The Journal of clinical investigation 118 (6), 2121-2131, 2008 | 188 | 2008 |
| Tristetraprolin binds to the 3′-untranslated region of cyclooxygenase-2 mRNA: a polyadenylation variant in a cancer cell line lacks the binding site H Sawaoka, DA Dixon, JA Oates, O Boutaud Journal of Biological Chemistry 278 (16), 13928-13935, 2003 | 175 | 2003 |
| Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure O Boutaud, KP Moore, BJ Reeder, D Harry, AJ Howie, S Wang, ... Proceedings of the National Academy of Sciences 107 (6), 2699-2704, 2010 | 172 | 2010 |
| Mechanism-based therapeutic approaches to rhabdomyolysis-induced renal failure O Boutaud, LJ Roberts II Free Radical Biology and Medicine 51 (5), 1062-1067, 2011 | 155 | 2011 |
| Identification of a naturally occurring peroxidase-lipoxygenase fusion protein R Koljak, O Boutaud, BH Shieh, N Samel, AR Brash Science 277 (5334), 1994-1996, 1997 | 146 | 1997 |
| Effects of reactive γ‐ketoaldehydes formed by the isoprostane pathway (isoketals) and cyclooxygenase pathway (levuglandins) on proteasome function SS Davies, V Amarnath, KS Montine, N Bernoud‐Hubac, O Boutaud, ... The FASEB Journal 16 (7), 715-717, 2002 | 129 | 2002 |
| Formation of highly reactive γ-ketoaldehydes (neuroketals) as products of the neuroprostane pathway N Bernoud-Hubac, SS Davies, O Boutaud, TJ Montine, LJ Roberts Journal of Biological Chemistry 276 (33), 30964-30970, 2001 | 117 | 2001 |
| Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling NS Woodling, Q Wang, PG Priyam, P Larkin, J Shi, JU Johansson, ... Journal of Neuroscience 34 (17), 5882-5894, 2014 | 112 | 2014 |
| Modification of proteins by isoketal-containing oxidized phospholipids CJ Brame, O Boutaud, SS Davies, T Yang, JA Oates, D Roden, ... Journal of Biological Chemistry 279 (14), 13447-13451, 2004 | 112 | 2004 |
| Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer’s disease model mice NS Woodling, D Colas, Q Wang, P Minhas, M Panchal, X Liang, ... Brain 139 (7), 2063-2081, 2016 | 95 | 2016 |
| Prostaglandin H2 (PGH2) accelerates formation of amyloid β1−42 oligomers O Boutaud, JJ Ou, P Chaurand, RM Caprioli, TJ Montine, JA Oates Journal of neurochemistry 82 (4), 1003-1006, 2002 | 90 | 2002 |
| Pyridoxamine Analogues Scavenge Lipid-Derived γ-Ketoaldehydes and Protect against H2O2-Mediated Cytotoxicity SS Davies, EJ Brantley, PA Voziyan, V Amarnath, I Zagol-Ikapitte, ... Biochemistry 45 (51), 15756-15767, 2006 | 88 | 2006 |
| Prostaglandin H2‐derived adducts of proteins correlate with Alzheimer's disease severity I Zagol‐Ikapitte, TS Masterson, V Amarnath, TJ Montine, KI Andreasson, ... Journal of neurochemistry 94 (4), 1140-1145, 2005 | 84 | 2005 |
| Characterization of the Lysyl Adducts Formed from Prostaglandin H2 via the Levuglandin Pathway O Boutaud, CJ Brame, RG Salomon, LJ Roberts, JA Oates Biochemistry 38 (29), 9389-9396, 1999 | 80 | 1999 |
| Purification and Catalytic Activities of the Two Domains of the Allene Oxide Synthase-Lipoxygenase Fusion Protein of the CoralPlexaura homomalla O Boutaud, AR Brash Journal of Biological Chemistry 274 (47), 33764-33770, 1999 | 79 | 1999 |
| Characterization of scavengers of γ-ketoaldehydes that do not inhibit prostaglandin biosynthesis I Zagol-Ikapitte, V Amarnath, M Bala, LJ Roberts, JA Oates, O Boutaud Chemical research in toxicology 23 (1), 240-250, 2010 | 76 | 2010 |
| Protease-Activated Receptor Signaling in Platelets Activates Cytosolic Phospholipase A2α Differently for Cyclooxygenase-1 and 12-Lipoxygenase Catalysis M Holinstat, O Boutaud, PL Apopa, J Vesci, M Bala, JA Oates, HE Hamm Arteriosclerosis, thrombosis, and vascular biology 31 (2), 435-442, 2011 | 67 | 2011 |
