Crystal structure of the Xrcc4 DNA repair protein and implications for end joining MS Junop, M Modesti, A Guarné, R Ghirlando, M Gellert, W Yang The EMBO journal 19 (22), 5962-5970, 2000 | 230 | 2000 |
Structure of the MutL C‐terminal domain: a model of intact MutL and its roles in mismatch repair A Guarné, S Ramon‐Maiques, EM Wolff, R Ghirlando, X Hu, JH Miller, ... The EMBO journal 23 (21), 4134-4145, 2004 | 214 | 2004 |
Structure of the foot‐and‐mouth disease virus leader protease: a papain‐like fold adapted for self‐processing and eIF4G recognition A Guarné, J Tormo, R Kirchweger, D Pfistermueller, I Fita, T Skern The EMBO journal 17 (24), 7469-7479, 1998 | 188 | 1998 |
Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP DHS Li, YS Chung, M Gloyd, E Joseph, R Ghirlando, GD Wright, ... Chemistry & biology 17 (9), 959-969, 2010 | 176 | 2010 |
Structure of the endonuclease domain of MutL: unlicensed to cut MC Pillon, JJ Lorenowicz, M Uckelmann, AD Klocko, RR Mitchell, ... Molecular cell 39 (1), 145-151, 2010 | 154 | 2010 |
Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease MV Rogacheva, CM Manhart, C Chen, A Guarne, J Surtees, E Alani Journal of Biological Chemistry 289 (9), 5664-5673, 2014 | 152 | 2014 |
The structures of picornaviral proteinases J Seipelt, A Guarné, E Bergmann, M James, W Sommergruber, I Fita, ... Virus research 62 (2), 159-168, 1999 | 148 | 1999 |
ClpP: a structurally dynamic protease regulated by AAA+ proteins JA Alexopoulos, A Guarné, J Ortega Journal of structural biology 179 (2), 202-210, 2012 | 144 | 2012 |
Structure and function of the N‐terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase A Guarné, MS Junop, W Yang The EMBO journal 20 (19), 5521-5531, 2001 | 144 | 2001 |
Molecular basis of human CD22 function and therapeutic targeting J Ereño-Orbea, T Sicard, H Cui, MT Mazhab-Jafari, S Benlekbir, A Guarné, ... Nature communications 8 (1), 764, 2017 | 138 | 2017 |
Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity H Huang, E Zeqiraj, B Dong, BK Jha, NM Duffy, S Orlicky, ... Molecular cell 53 (2), 221-234, 2014 | 135 | 2014 |
Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility JM Reimer, M Eivaskhani, I Harb, A Guarné, M Weigt, TM Schmeing Science 366 (6466), 2019 | 105 | 2019 |
The endonuclease domain of MutL interacts with the β sliding clamp MC Pillon, JH Miller, A Guarné DNA repair 10 (1), 87-93, 2011 | 83 | 2011 |
The PMS2 subunit of human MutLα contains a metal ion binding domain of the iron-dependent repressor protein family J Kosinski, G Plotz, A Guarné, JM Bujnicki, P Friedhoff Journal of molecular biology 382 (3), 610-627, 2008 | 78 | 2008 |
Structural and biochemical features distinguish the foot-and-mouth disease virus leader proteinase from other papain-like enzymes A Guarné, B Hampoelz, W Glaser, X Carpena, J Tormo, I Fita, T Skern Journal of molecular biology 302 (5), 1227-1240, 2000 | 77 | 2000 |
Crystal structure of a SeqA–N filament: implications for DNA replication and chromosome organization A Guarné, T Brendler, Q Zhao, R Ghirlando, S Austin, W Yang The EMBO journal 24 (8), 1502-1511, 2005 | 74 | 2005 |
The functions of MutL in mismatch repair: the power of multitasking A Guarné Progress in molecular biology and translational science 110, 41-70, 2012 | 63 | 2012 |
Insights into negative modulation of E. coli replication initiation from the structure of SeqA–hemimethylated DNA complex A Guarné, Q Zhao, R Ghirlando, W Yang Nature Structural & Molecular Biology 9 (11), 839, 2002 | 60 | 2002 |
Mismatch repair in Gram-positive bacteria JS Lenhart, MC Pillon, A Guarné, JS Biteen, LA Simmons Research in microbiology 167 (1), 4-12, 2016 | 59 | 2016 |
A novel nucleoid-associated protein specific to the actinobacteria JP Swiercz, T Nanji, M Gloyd, A Guarne, MA Elliot Nucleic acids research 41 (7), 4171-4184, 2013 | 58 | 2013 |