Immortalized epithelial cells derived from human colon biopsies express stem cell markers and differentiate in vitro AI Roig, U Eskiocak, SK Hight, SB Kim, O Delgado, RF Souza, ... Gastroenterology 138 (3), 1012-1021. e5, 2010 | 192 | 2010 |
Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation SB Kim, RK Pandita, U Eskiocak, P Ly, A Kaisani, R Kumar, C Cornelius, ... Proceedings of the National Academy of Sciences 109 (43), E2949-E2955, 2012 | 161 | 2012 |
Human melanoma metastasis in NSG mice correlates with clinical outcome in patients E Quintana, E Piskounova, M Shackleton, D Weinberg, U Eskiocak, ... Science translational medicine 4 (159), 159ra149-159ra149, 2012 | 119 | 2012 |
Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions Y Zhao, E Abreu, J Kim, G Stadler, U Eskiocak, MP Terns, RM Terns, ... Molecular cell 42 (3), 297-307, 2011 | 111 | 2011 |
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells KK Payne, JA Mine, S Biswas, RA Chaurio, A Perales-Puchalt, ... Science 369 (6506), 942-949, 2020 | 93 | 2020 |
Gliomas interact with non-glioma brain cells via extracellular vesicles X Gao, Z Zhang, T Mashimo, B Shen, J Nyagilo, H Wang, Y Wang, Z Liu, ... Cell reports 30 (8), 2489-2500. e5, 2020 | 73 | 2020 |
Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer L Zhang, PC Theodoropoulos, U Eskiocak, W Wang, YA Moon, B Posner, ... Science translational medicine 8 (361), 361ra140-361ra140, 2016 | 70 | 2016 |
Label-free detection of telomerase activity using guanine electrochemical oxidation signal U Eskiocak, D Ozkan-Ariksoysal, M Ozsoz, HA Öktem Analytical chemistry 79 (22), 8807-8811, 2007 | 65 | 2007 |
Biomarker accessible and chemically addressable mechanistic subtypes of BRAF melanoma B Eskiocak, EA McMillan, S Mendiratta, RK Kollipara, H Zhang, ... Cancer discovery 7 (8), 832-851, 2017 | 60 | 2017 |
Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma H Potu, LF Peterson, M Kandarpa, A Pal, H Sun, A Durham, PW Harms, ... Nature communications 8 (1), 14449, 2017 | 57 | 2017 |
Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma U Eskiocak, V Ramesh, JG Gill, Z Zhao, SW Yuan, M Wang, T Vandergriff, ... Nature communications 7 (1), 12336, 2016 | 57 | 2016 |
Characterization of aneuploid populations with trisomy 7 and 20 derived from diploid human colonic epithelial cells P Ly, U Eskiocak, SB Kim, AI Roig, SK Hight, DR Lulla, YS Zou, K Batten, ... Neoplasia 13 (4), 348-IN17, 2011 | 53 | 2011 |
TRPML1 promotes protein homeostasis in melanoma cells by negatively regulating MAPK and mTORC1 signaling SY Kasitinon, U Eskiocak, M Martin, D Bezwada, V Khivansara, ... Cell reports 28 (9), 2293-2305. e9, 2019 | 47 | 2019 |
Interpretable deep learning uncovers cellular properties in label-free live cell images that are predictive of highly metastatic melanoma A Zaritsky, AR Jamieson, ES Welf, A Nevarez, J Cillay, U Eskiocak, ... Cell systems 12 (7), 733-747. e6, 2021 | 46 | 2021 |
CDDO-Me protects against space radiation-induced transformation of human colon epithelial cells U Eskiocak, SB Kim, AI Roig, E Kitten, K Batten, C Cornelius, YS Zou, ... Radiation research 174 (1), 27-36, 2010 | 44 | 2010 |
Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity U Eskiocak, W Guzman, B Wolf, C Cummings, L Milling, HJ Wu, M Ophir, ... JCI insight 5 (5), 2020 | 42 | 2020 |
Short hairpin RNA screen indicates that Klotho beta/FGF19 protein overcomes stasis in human colonic epithelial cells J Kim, U Eskiocak, G Stadler, Z Lou, M Kuro-o, JW Shay, WE Wright Journal of Biological Chemistry 286 (50), 43294-43300, 2011 | 40 | 2011 |
Digoxin plus trametinib therapy achieves disease control in BRAF wild-type metastatic melanoma patients AE Frankel, U Eskiocak, JG Gill, S Yuan, V Ramesh, TW Froehlich, C Ahn, ... Neoplasia 19 (4), 255-260, 2017 | 39 | 2017 |
Functional parsing of driver mutations in the colorectal cancer genome reveals numerous suppressors of anchorage-independent growth U Eskiocak, SB Kim, P Ly, AI Roig, S Biglione, K Komurov, C Cornelius, ... Cancer research 71 (13), 4359-4365, 2011 | 35 | 2011 |
Effect of doxorubicin on telomerase activity and apoptotic gene expression in doxorubicin-resistant and-sensitive MCF-7 cells: an experimental study U Eskiocak, OD İşeri, MD Kars, A Biçer, U Gunduz Chemotherapy 54 (3), 209-216, 2008 | 26 | 2008 |