| Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8 F Heil, H Hemmi, H Hochrein, F Ampenberger, C Kirschning, S Akira, ... Science 303 (5663), 1526-1529, 2004 | 5084 | 2004 |
| Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition S Bauer, CJ Kirschning, H Häcker, V Redecke, S Hausmann, S Akira, ... Proceedings of the national academy of sciences 98 (16), 9237-9242, 2001 | 1979 | 2001 |
| Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848 M Jurk, F Heil, J Vollmer, C Schetter, AM Krieg, H Wagner, G Lipford, ... Nature immunology 3 (6), 499-499, 2002 | 1339 | 2002 |
| Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells T Sparwasser, ES Koch, RM Vabulas, K Heeg, GB Lipford, JW Ellwart, ... European journal of immunology 28 (6), 2045-2054, 1998 | 1048 | 1998 |
| CpG‐DNA‐specific activation of antigen‐presenting cells requires stress kinase activity and is preceded by non‐specific endocytosis and endosomal maturation H Häcker, H Mischak, T Miethke, S Liptay, R Schmid, T Sparwasser, ... The EMBO journal, 1998 | 881 | 1998 |
| The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily F Heil, P Ahmad‐Nejad, H Hemmi, H Hochrein, F Ampenberger, T Gellert, ... European journal of immunology 33 (11), 2987-2997, 2003 | 735 | 2003 |
| Toll‐like receptor 9 binds single‐stranded CpG‐DNA in a sequence‐and pH‐dependent manner M Rutz, J Metzger, T Gellert, P Luppa, GB Lipford, H Wagner, S Bauer European journal of immunology 34 (9), 2541-2550, 2004 | 668 | 2004 |
| Cutting edge: CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis S Zimmermann, O Egeter, S Hausmann, GB Lipford, M Röcken, ... The Journal of Immunology 160 (8), 3627-3630, 1998 | 630 | 1998 |
| Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides S Zwaveling, SCF Mota, J Nouta, M Johnson, GB Lipford, R Offringa, ... The Journal of Immunology 169 (1), 350-358, 2002 | 576 | 2002 |
| Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor‐α‐mediated shock T Sparwasser, T Miethke, G Lipford, A Erdmann, H Häcker, K Heeg, ... European journal of immunology 27 (7), 1671-1679, 1997 | 553 | 1997 |
| CpG‐containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants GB Lipford, M Bauer, C Blank, R Reiter, H Wagner, K Heeg European journal of immunology 27 (9), 2340-2344, 1997 | 529 | 1997 |
| Bacterial DNA causes septic shock T Sparwasser, T Miethke, G Lipford, K Borschert, H Häcker, K Heeg, ... Nature 386 (6623), 336-337, 1997 | 528 | 1997 |
| Bacterial CpG-DNA triggers activation and maturation of human CD11c−, CD123+ dendritic cells M Bauer, V Redecke, JW Ellwart, B Scherer, JP Kremer, H Wagner, ... The Journal of Immunology 166 (8), 5000-5007, 2001 | 415 | 2001 |
| Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses A Forsbach, JG Nemorin, C Montino, C Muller, U Samulowitz, AP Vicari, ... The Journal of Immunology 180 (6), 3729-3738, 2008 | 361 | 2008 |
| Immunostimulatory DNA: sequence‐dependent production of potentially harmful or useful cytokines GB Lipford, T Sparwasser, M Bauer, S Zimmermann, ES Koch, K Heeg, ... European journal of immunology 27 (12), 3420-3426, 1997 | 359 | 1997 |
| TLRs govern neutrophil activity in aspergillosis S Bellocchio, S Moretti, K Perruccio, F Fallarino, S Bozza, C Montagnoli, ... The Journal of Immunology 173 (12), 7406-7415, 2004 | 311 | 2004 |
| Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells T Decker, F Schneller, T Sparwasser, T Tretter, GB Lipford, H Wagner, ... Blood, The Journal of the American Society of Hematology 95 (3), 999-1006, 2000 | 300 | 2000 |
| Pharmaceutical compositions comprising a polynucleotide and optionally an antigen especially for vaccination H Wagner, G Lipford, K Heeg US Patent 7,001,890, 2006 | 261 | 2006 |
| Small molecule toll-like receptor (TLR) antagonists GB Lipford, A Forsbach, C Zepp US Patent 7,410,975, 2008 | 242 | 2008 |
| Bacterial CpG‐DNA activates dendritic cells in vivo: T helper cell‐independent cytotoxic T cell responses to soluble proteins T Sparwasser, RM Vabulas, B Villmow, GB Lipford, H Wagner European journal of immunology 30 (12), 3591-3597, 2000 | 230 | 2000 |
Hermann WagnerTUM Emeritus of Excellence: Med. Mikrobiologie , Immunolgy and HygieneVerified email at lrz.tu-muenchen.de
