A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients L Rosso, CS Brock, JM Gallo, A Saleem, PM Price, FE Turkheimer, ... Cancer research 69 (1), 120-127, 2009 | 189 | 2009 |
Tumor survivin is downregulated by the antisense oligonucleotide LY2181308: a proof-of-concept, first-in-human dose study DC Talbot, M Ranson, J Davies, M Lahn, S Callies, V André, S Kadam, ... Clinical Cancer Research 16 (24), 6150-6158, 2010 | 105 | 2010 |
Modulation of fluorouracil tissue pharmacokinetics by eniluracil: in-vivo imaging of drug action A Saleem, J Yap, S Osman, F Brady, SV Lucas, T Jones, PM Price, ... The Lancet 355 (9221), 2125-2131, 2000 | 103 | 2000 |
Metabolic activation of temozolomide measured in vivo using positron emission tomography A Saleem, GD Brown, F Brady, EO Aboagye, S Osman, SK Luthra, ... Cancer Research 63 (10), 2409-2415, 2003 | 100 | 2003 |
Pharmacokinetic evaluation of N-[2-(dimethylamino) ethyl] acridine-4-carboxamide in patients by positron emission tomography A Saleem, RJ Harte, JC Matthews, S Osman, F Brady, SK Luthra, ... Journal of clinical oncology 19 (5), 1421-1429, 2001 | 81 | 2001 |
Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer A Saleem, GE Searle, LM Kenny, M Huiban, K Kozlowski, AD Waldman, ... EJNMMI research 5, 1-10, 2015 | 72 | 2015 |
Clinical quantification of the integrin αvβ6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study) PT Lukey, C Coello, R Gunn, C Parker, FJ Wilson, A Saleem, N Garman, ... European Journal of Nuclear Medicine and Molecular Imaging 47, 967-979, 2020 | 55 | 2020 |
A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [11C]GSK2256098 NF Brown, M Williams, HT Arkenau, RA Fleming, J Tolson, L Yan, J Zhang, ... Neuro-oncology 20 (12), 1634-1642, 2018 | 53 | 2018 |
Translocator protein as an imaging marker of macrophage and stromal activation in rheumatoid arthritis pannus N Narayan, DR Owen, H Mandhair, E Smyth, F Carlucci, A Saleem, ... Journal of Nuclear Medicine 59 (7), 1125-1132, 2018 | 52 | 2018 |
Extraction of 5-fluorouracil by tumor and liver: a noninvasive positron emission tomography study of patients with gastrointestinal cancer EO Aboagye, A Saleem, VJ Cunningham, S Osman, PM Price Cancer research 61 (13), 4937-4941, 2001 | 52 | 2001 |
Carbogen and nicotinamide increase blood flow and 5-fluorouracil delivery but not 5-fluorouracil retention in colorectal cancer metastases in patients N Gupta, A Saleem, B Kötz, S Osman, EO Aboagye, R Phillips, ... Clinical cancer research 12 (10), 3115-3123, 2006 | 51 | 2006 |
Use of positron emission tomography in pharmacokinetic studies to investigate therapeutic advantage in a phase I study of 120-hour intravenous infusion XR5000 DJ Propper, J De Bono, A Saleem, S Ellard, E Flanagan, J Paul, ... Journal of clinical oncology 21 (2), 203-210, 2003 | 49 | 2003 |
A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled … TM Maher, JK Simpson, JC Porter, FJ Wilson, R Chan, R Eames, Y Cui, ... Respiratory research 21, 1-9, 2020 | 48 | 2020 |
Clinical translation of a click-labeled 18F-octreotate radioligand for imaging neuroendocrine tumors SR Dubash, N Keat, P Mapelli, F Twyman, L Carroll, K Kozlowski, ... Journal of Nuclear Medicine 57 (8), 1207-1213, 2016 | 48 | 2016 |
Clinical translation of a click-labeled 18F-octreotate radioligand for imaging neuroendocrine tumors SR Dubash, N Keat, P Mapelli, F Twyman, L Carroll, K Kozlowski, ... Journal of Nuclear Medicine 57 (8), 1207-1213, 2016 | 48 | 2016 |
Radiolabelled tracers and anticancer drugs for assessment of therapeutic efficacy using PET F Brady, SK Luthra, GD Brown, S Osman, E Aboagye, A Saleem, PM Price Current Pharmaceutical Design 7 (18), 1863-1892, 2001 | 47 | 2001 |
Serotonin release measured in the human brain: a PET study with [11C]CIMBI-36 and d-amphetamine challenge D Erritzoe, AH Ashok, GE Searle, A Colasanti, S Turton, Y Lewis, ... Neuropsychopharmacology 45 (5), 804-810, 2020 | 44 | 2020 |
Clinical molecular imaging with positron emission tomography A Saleem, N Charnley, P Price European Journal of Cancer 42 (12), 1720-1727, 2006 | 44 | 2006 |
In vivo monitoring of drugs using radiotracer techniques A Saleem, EO Aboagye, PM Price Advanced drug delivery reviews 41 (1), 21-39, 2000 | 42 | 2000 |
Computed tomography overestimation of esophageal tumor length: Implications for radiotherapy planning K Sillah, LR Williams, HU Laasch, A Saleem, G Watkins, SA Pritchard, ... World Journal of Gastrointestinal Oncology 2 (4), 197, 2010 | 33 | 2010 |