| A fragment-based method to discover irreversible covalent inhibitors of cysteine proteases SG Kathman, Z Xu, AV Statsyuk Journal of medicinal chemistry 57 (11), 4969-4974, 2014 | 185 | 2014 |
| Synthesis of Bistramide A AV Statsuk, D Liu, SA Kozmin Journal of the American Chemical Society 126 (31), 9546-9547, 2004 | 144 | 2004 |
| A small molecule that switches a ubiquitin ligase from a processive to a distributive enzymatic mechanism SG Kathman, I Span, AT Smith, Z Xu, J Zhan, AC Rosenzweig, ... Journal of the American Chemical Society 137 (39), 12442-12445, 2015 | 101 | 2015 |
| Actin is the primary cellular receptor of bistramide A AV Statsuk, R Bai, JL Baryza, VA Verma, E Hamel, PA Wender, ... Nature Chemical Biology 1 (7), 383-8, 2005 | 100 | 2005 |
| Tuning a three-component reaction for trapping kinase substrate complexes AV Statsuk, DJ Maly, MA Seeliger, MA Fabian, WH Biggs, DJ Lockhart, ... Journal of the American Chemical Society 130 (51), 17568-74, 2008 | 88 | 2008 |
| Covalent tethering of fragments for covalent probe discovery SG Kathman, AV Statsyuk MedChemComm 7 (4), 576-585, 2016 | 86 | 2016 |
| Reaction of 2-Methylene-1,3-dicarbonyl Compounds Containing a CF3-Group with 1,3-Dienes VG Nenajdenko, AV Statsuk, ES Balenkova Tetrahedron 56 (35), 6549-6556, 2000 | 78 | 2000 |
| Development of activity-based probes for ubiquitin and ubiquitin-like protein signaling pathways H An, AV Statsyuk Journal of the American Chemical Society 135 (45), 16948-16962, 2013 | 55 | 2013 |
| An inhibitor of ubiquitin conjugation and aggresome formation H An, AV Statsyuk Chemical science 6 (9), 5235-5245, 2015 | 54 | 2015 |
| Crosstalk between kinases and Nedd4 family ubiquitin ligases H An, DT Krist, AV Statsyuk Molecular bioSystems 10 (7), 1643-1657, 2014 | 44 | 2014 |
| Dissecting the specificity of adenosyl sulfamate inhibitors targeting the ubiquitin-activating enzyme M Misra, M Kuhn, M Löbel, H An, AV Statsyuk, C Sotriffer, H Schindelin Structure 25 (7), 1120-1129. e3, 2017 | 38 | 2017 |
| Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies K Juenemann, AHP Jansen, L van Riel, R Merkx, MPC Mulder, H An, ... Scientific reports 8 (1), 1405, 2018 | 37 | 2018 |
| Covalent-fragment screening of BRD4 identifies a ligandable site orthogonal to the acetyl-lysine binding sites MD Olp, DJ Sprague, CJ Goetz, SG Kathman, SL Wynia-Smith, ... ACS chemical biology 15 (4), 1036-1049, 2020 | 36 | 2020 |
| Protein ubiquitination and formation of polyubiquitin chains without ATP, E1 and E2 enzymes S Park, DT Krist, AV Statsyuk Chemical Science 6 (3), 1770-1779, 2015 | 31 | 2015 |
| UbMES and UbFluor: novel probes for ring-between-ring (RBR) E3 ubiquitin ligase PARKIN S Park, PK Foote, DT Krist, SE Rice, AV Statsyuk Journal of Biological Chemistry 292 (40), 16539-16553, 2017 | 30 | 2017 |
| UbFluor: a mechanism-based probe for HECT E3 ligases DT Krist, S Park, GH Boneh, SE Rice, AV Statsyuk Chemical science 7 (8), 5587-5595, 2016 | 28 | 2016 |
| Facile synthesis of covalent probes to capture enzymatic intermediates during E1 enzyme catalysis H An, AV Statsyuk Chemical communications 52 (12), 2477-2480, 2016 | 25 | 2016 |
| Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments SR Chowdhury, S Kennedy, K Zhu, R Mishra, P Chuong, A Nguyen, ... Bioorganic & medicinal chemistry letters 29 (1), 36-39, 2019 | 23 | 2019 |
| Identification of non-peptidic cysteine reactive fragments as inhibitors of cysteine protease rhodesain D McShan, S Kathman, B Lowe, Z Xu, J Zhan, A Statsyuk, IV Ogungbe Bioorganic & medicinal chemistry letters 25 (20), 4509-4512, 2015 | 20 | 2015 |
| Mapping low-affinity/high-specificity peptide–protein interactions using ligand-footprinting mass spectrometry BW Parker, EJ Goncz, DT Krist, AV Statsyuk, AI Nesvizhskii, EL Weiss Proceedings of the National Academy of Sciences 116 (42), 21001-21011, 2019 | 18 | 2019 |
