| Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease E Giacomelli, V Meraviglia, G Campostrini, A Cochrane, X Cao, ... Cell stem cell 26 (6), 862-879. e11, 2020 | 410 | 2020 |
| Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells E Giacomelli, M Bellin, L Sala, BJ Van Meer, LGJ Tertoolen, VV Orlova, ... Development 144 (6), 1008-1017, 2017 | 301 | 2017 |
| MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo L Sala, BJ Van Meer, LGJ Tertoolen, J Bakkers, M Bellin, RP Davis, ... Circulation research 122 (3), e5-e16, 2018 | 275 | 2018 |
| Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come? L Sala, M Bellin, CL Mummery British journal of pharmacology 174 (21), 3749-3765, 2017 | 134 | 2017 |
| Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes M Rocchetti, L Sala, L Dreizehnter, L Crotti, D Sinnecker, M Mura, ... Cardiovascular research 113 (5), 531-541, 2017 | 127 | 2017 |
| A new hERG allosteric modulator rescues genetic and drug‐induced long‐QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells L Sala, Z Yu, D Ward‐van Oostwaard, JPD van Veldhoven, A Moretti, ... EMBO molecular medicine 8 (9), 1065-1081, 2016 | 92 | 2016 |
| From patient-specific induced pluripotent stem cells to clinical translation in long QT syndrome Type 2 PJ Schwartz, M Gnecchi, F Dagradi, S Castelletti, G Parati, C Spazzolini, ... European heart journal 40 (23), 1832-1836, 2019 | 79 | 2019 |
| Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation R Rizzi, E Di Pasquale, P Portararo, R Papait, P Cattaneo, MVG Latronico, ... Cell Death & Differentiation 19 (7), 1162-1174, 2012 | 72 | 2012 |
| Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes BJ van Meer, A Krotenberg, L Sala, RP Davis, T Eschenhagen, ... Nature Communications 10 (1), 4325, 2019 | 64 | 2019 |
| Ranolazine prevents INaL enhancement and blunts myocardial remodelling in a model of pulmonary hypertension M Rocchetti, L Sala, R Rizzetto, LI Staszewsky, M Alemanni, V Zambelli, ... Cardiovascular research 104 (1), 37-48, 2014 | 52 | 2014 |
| Electrophysiological analysis of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) using multi-electrode arrays (MEAs) L Sala, D Ward-van Oostwaard, LGJ Tertoolen, CL Mummery, M Bellin JoVE (Journal of Visualized Experiments), e55587, 2017 | 49 | 2017 |
| MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier … YK Lee, L Sala, M Mura, M Rocchetti, M Pedrazzini, X Ran, TSH Mak, ... Cardiovascular Research 117 (3), 767-779, 2021 | 41 | 2021 |
| Precision medicine and cardiac channelopathies: when dreams meet reality M Gnecchi, L Sala, PJ Schwartz European heart journal 42 (17), 1661-1675, 2021 | 40 | 2021 |
| IKr Impact on Repolarization and Its Variability Assessed by Dynamic Clamp C Altomare, C Bartolucci, L Sala, J Bernardi, G Mostacciuolo, M Rocchetti, ... Circulation: Arrhythmia and Electrophysiology 8 (5), 1265-1275, 2015 | 40 | 2015 |
| Long QT syndrome modelling with cardiomyocytes derived from human-induced pluripotent stem cells L Sala, M Gnecchi, PJ Schwartz Arrhythmia & electrophysiology review 8 (2), 105, 2019 | 38 | 2019 |
| Calmodulinopathy: a novel, life-threatening clinical entity affecting the young MC Kotta, L Sala, A Ghidoni, B Badone, C Ronchi, G Parati, A Zaza, ... Frontiers in cardiovascular medicine 5, 175, 2018 | 34 | 2018 |
| Isogenic sets of hiPSC-CMs harboring distinct KCNH2 mutations differ functionally and in susceptibility to drug-induced arrhythmias KO Brandão, L van den Brink, DC Miller, C Grandela, BJ van Meer, ... Stem cell reports 15 (5), 1127-1139, 2020 | 30 | 2020 |
| Calmodulinopathy: functional effects of CALM mutations and their relationship with clinical phenotypes B Badone, C Ronchi, MC Kotta, L Sala, A Ghidoni, L Crotti, A Zaza Frontiers in Cardiovascular Medicine 5, 176, 2018 | 28 | 2018 |
| Action potential contour contributes to species differences in repolarization response to β-adrenergic stimulation L Sala, B Hegyi, C Bartolucci, C Altomare, M Rocchetti, K Váczi, ... EP Europace 20 (9), 1543-1552, 2018 | 23 | 2018 |
| Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell‐Derived Cardiomyocytes to Zebrafish and Human Hearts BJ van Meer, L Sala, LGJ Tertoolen, GL Smith, FL Burton, CL Mummery Current Protocols in Human Genetics 99 (1), e67, 2018 | 17 | 2018 |
C. MummeryLeiden University Medical Centre and University of TwenteVerified email at lumc.nl
