Mapping interactions with the chaperone network reveals factors that protect against tau aggregation SA Mok, C Condello, R Freilich, A Gillies, T Arhar, J Oroz, H Kadavath, ... Nature structural & molecular biology 25 (5), 384-393, 2018 | 131 | 2018 |
Pathogenic tau impairs axon initial segment plasticity and excitability homeostasis PD Sohn, CTL Huang, R Yan, L Fan, TE Tracy, CM Camargo, ... Neuron 104 (3), 458-470. e5, 2019 | 101 | 2019 |
Protein–protein interactions in the molecular chaperone network R Freilich, T Arhar, JL Abrams, JE Gestwicki Accounts of chemical research 51 (4), 940-949, 2018 | 95 | 2018 |
The interactions of molecular chaperones with client proteins: why are they so weak? T Arhar, A Shkedi, CM Nadel, JE Gestwicki Journal of Biological Chemistry 297 (5), 2021 | 29 | 2021 |
Insertion of perilipin 3 into a glycero (phospho) lipid monolayer depends on lipid headgroup and acyl chain species [S] M Mirheydari, SS Rathnayake, H Frederick, T Arhar, EK Mann, S Cocklin, ... Journal of lipid research 57 (8), 1465-1476, 2016 | 22 | 2016 |
Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance D Mavor, KA Barlow, D Asarnow, Y Birman, D Britain, W Chen, EM Green, ... Biology Open 7 (7), bio036103, 2018 | 18 | 2018 |
Inhibition of toxic IAPP amyloid by extracts of common fruits PY Kao, E Green, C Pereira, S Ekimura, D Juarez, T Whyte, T Arhar, ... Journal of functional foods 12, 450-457, 2015 | 18 | 2015 |
Two distinct classes of cochaperones compete for the EEVD motif in heat shock protein 70 to tune its chaperone activities OT Johnson, CM Nadel, EC Carroll, T Arhar, JE Gestwicki Journal of Biological Chemistry 298 (3), 2022 | 16 | 2022 |
Robust sequence determinants of α-synuclein toxicity in yeast implicate membrane binding RW Newberry, T Arhar, J Costello, GC Hartoularos, AM Maxwell, ... ACS chemical biology 15 (8), 2137-2153, 2020 | 11 | 2020 |
Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability J Abrams, T Arhar, SA Mok, IR Taylor, M Kampmann, JE Gestwicki Cell Stress and Chaperones 26 (2), 443-452, 2021 | 5 | 2021 |
Two distinct classes of co-chaperones compete for the EEVD motif in heat shock protein 70 (Hsp70) to tune its activity OT Johnson, CM Nadel, EC Carroll, T Arhar, JE Gestwicki bioRxiv, 2021.10. 18.464838, 2021 | 1 | 2021 |