| Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation Z He, JL Guo, JD McBride, S Narasimhan, H Kim, L Changolkar, B Zhang, ... Nature medicine 24 (1), 29-38, 2018 | 556 | 2018 |
| Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice JL Guo, S Narasimhan, L Changolkar, Z He, A Stieber, B Zhang, ... Journal of Experimental Medicine 213 (12), 2635-2654, 2016 | 401 | 2016 |
| Pathological tau strains from human brains recapitulate the diversity of tauopathies in nontransgenic mouse brain S Narasimhan, JL Guo, L Changolkar, A Stieber, JD McBride, LV Silva, ... Journal of neuroscience 37 (47), 11406-11423, 2017 | 359 | 2017 |
| Essential role of TRPC6 channels in G2/M phase transition and development of human glioma X Ding, Z He, K Zhou, J Cheng, H Yao, D Lu, R Cai, Y Jin, B Dong, Y Xu, ... JNCI: Journal of the National Cancer Institute 102 (14), 1052-1068, 2010 | 201 | 2010 |
| TRPC6 channels promote dendritic growth via the CaMKIV-CREB pathway Y Tai, S Feng, R Ge, W Du, X Zhang, Z He, Y Wang Journal of cell science 121 (14), 2301-2307, 2008 | 186 | 2008 |
| Transmission of tauopathy strains is independent of their isoform composition Z He, JD McBride, H Xu, L Changolkar, S Kim, B Zhang, S Narasimhan, ... Nature communications 11 (1), 7, 2020 | 110 | 2020 |
| Critical role of TRPC6 channels in G2 phase transition and the development of human oesophageal cancer Y Shi, X Ding, ZH He, KC Zhou, Q Wang, YZ Wang Gut 58 (11), 1443-1450, 2009 | 102 | 2009 |
| Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau NF Darwich, JM Phan, B Kim, ER Suh, JD Papatriantafyllou, L Changolkar, ... Science 370 (6519), eaay8826, 2020 | 96 | 2020 |
| TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production J Wang, R Lu, J Yang, H Li, Z He, N Jing, X Wang, Y Wang Nature communications 6 (1), 8876, 2015 | 73 | 2015 |
| SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation G Xu, Y Li, S Zhang, H Peng, Y Wang, D Li, T Jin, Z He, Y Tong, C Qi, ... Cell research 31 (12), 1230-1243, 2021 | 70 | 2021 |
| Modulating TRADD to restore cellular homeostasis and inhibit apoptosis D Xu, H Zhao, M Jin, H Zhu, B Shan, J Geng, SA Dziedzic, P Amin, ... Nature 587 (7832), 133-138, 2020 | 63 | 2020 |
| Targeting TRPC6 channels in oesophageal carcinoma growth X Ding, Z He, Y Shi, Q Wang, Y Wang Expert opinion on therapeutic targets 14 (5), 513-527, 2010 | 60 | 2010 |
| TRPC5 channel is the mediator of neurotrophin-3 in regulating dendritic growth via CaMKIIα in rat hippocampal neurons Z He, C Jia, S Feng, K Zhou, Y Tai, X Bai, Y Wang Journal of Neuroscience 32 (27), 9383-9395, 2012 | 52 | 2012 |
| Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology S Zhang, Y Zhu, J Lu, Z Liu, AG Lobato, W Zeng, J Liu, J Qiang, S Zeng, ... Elife 11, e79898, 2022 | 10 | 2022 |
| Insoluble tau from human FTDP-17 cases exhibit unique transmission properties in vivo SA Weitzman, S Narasimhan, Z He, L Changolkar, JD McBride, B Zhang, ... Journal of Neuropathology & Experimental Neurology 79 (9), 941-949, 2020 | 9 | 2020 |
| Concomitant protein pathogenesis in Parkinson’s disease and perspective mechanisms Y Han, Z He Frontiers in Aging Neuroscience 15, 1189809, 2023 | 5 | 2023 |
| Ca2+ signaling initiated by canonical transient receptor potential channels in dendritic development S Feng, Z He, H Li, Y Wang Neuroscience Bulletin 31, 351-356, 2015 | 5 | 2015 |
| A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury X Zhao, W Zeng, H Xu, Z Sun, Y Hu, B Peng, JD McBride, J Duan, J Deng, ... Science translational medicine 15 (713), eabo6889, 2023 | 4 | 2023 |
| TRPC channel downstream signaling cascades Z He Transient Receptor Potential Canonical Channels and Brain Diseases, 25-33, 2017 | 4 | 2017 |
| MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons H Xu, Q Qiu, P Hu, K Hoxha, E Jang, M O’Reilly, C Kim, Z He, N Marotta, ... Acta Neuropathologica 147 (1), 55, 2024 | | 2024 |
Virginia LeeProfessor of Pathology and Laboratory Medicine, University of PennsylvaniaVerified email at upenn.edu
