Loss of BAP1 function leads to EZH2-dependent transformation LM LaFave, W Béguelin, R Koche, M Teater, B Spitzer, A Chramiec, ... Nature medicine 21 (11), 1344-1349, 2015 | 355 | 2015 |
Transpeptidase-Mediated Incorporation of d-Amino Acids into Bacterial Peptidoglycan TJ Lupoli, H Tsukamoto, EH Doud, TSA Wang, S Walker, D Kahne Journal of the American Chemical Society 133 (28), 10748-10751, 2011 | 155 | 2011 |
Complete characterization of the seventeen step moenomycin biosynthetic pathway B Ostash, EH Doud, C Lin, I Ostash, DL Perlstein, S Fuse, M Wolpert, ... Biochemistry 48 (37), 8830-8841, 2009 | 95 | 2009 |
Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin R Makitrynskyy, B Ostash, O Tsypik, Y Rebets, E Doud, T Meredith, ... Open biology 3 (10), 130121, 2013 | 78 | 2013 |
Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors CM Gampe, H Tsukamoto, EH Doud, S Walker, D Kahne Journal of the American Chemical Society 135 (10), 3776-3779, 2013 | 61 | 2013 |
The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases DL Perlstein, TS Andrew Wang, EH Doud, D Kahne, S Walker Journal of the American Chemical Society 132 (1), 48-49, 2010 | 55 | 2010 |
Cryo-EM structures of prion protein filaments from Gerstmann–Sträussler–Scheinker disease GI Hallinan, KA Ozcan, MR Hoq, L Cracco, FS Vago, SR Bharath, D Li, ... Acta Neuropathologica 144 (3), 509-520, 2022 | 41 | 2022 |
Mechanism of Inactivation of γ-Aminobutyric Acid Aminotransferase by (1S,3S)-3-Amino-4-difluoromethylene-1-cyclopentanoic Acid (CPP-115) H Lee, EH Doud, R Wu, R Sanishvili, JI Juncosa, D Liu, NL Kelleher, ... Journal of the American Chemical Society 137 (7), 2628-2640, 2015 | 37 | 2015 |
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity B Kumar, AK Adebayo, M Prasad, ML Capitano, R Wang, ... Science Advances 8 (2), eabh3375, 2022 | 31 | 2022 |
Design and mechanism of tetrahydrothiophene-based γ-aminobutyric acid aminotransferase inactivators HV Le, DD Hawker, R Wu, E Doud, J Widom, R Sanishvili, D Liu, ... Journal of the American Chemical Society 137 (13), 4525-4533, 2015 | 30 | 2015 |
The molecular biology of moenomycins: towards novel antibiotics based on inhibition of bacterial peptidoglycan glycosyltransferases B Ostash, E Doud, V Fedorenko Biological Chemistry 391 (5), 499-504, 2010 | 25 | 2010 |
A rapid method for relative quantification of N-glycans from a therapeutic monoclonal antibody during trastuzumab biosimilar development Z Segu, T Stone, C Berdugo, A Roberts, E Doud, Y Li MAbs 12 (1), 1750794, 2020 | 23 | 2020 |
ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export B Ostash, E Doud, S Walker Archives of microbiology 194, 915-922, 2012 | 22 | 2012 |
Two distinct mechanisms for TIM barrel prenyltransferases in bacteria EH Doud, DL Perlstein, M Wolpert, DE Cane, S Walker Journal of the American Chemical Society 133 (5), 1270-1273, 2011 | 22 | 2011 |
Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid H Lee, HV Le, R Wu, E Doud, R Sanishvili, JF Kellie, PD Compton, ... ACS chemical biology 10 (9), 2087-2098, 2015 | 17 | 2015 |
A multi‐omic analysis of the dorsal striatum in an animal model of divergent genetic risk for alcohol use disorder GG Grecco, DL Haggerty, EH Doud, BM Fritz, F Yin, H Hoffman, ... Journal of neurochemistry 157 (4), 1013-1031, 2021 | 15 | 2021 |
Rapid global characterization of immunoglobulin G1 following oxidative stress Y Chen, E Doud, T Stone, L Xin, W Hong, Y Li MAbs 11 (6), 1089-1100, 2019 | 14 | 2019 |
Moenomycin analogs, methods of synthesis, and uses thereof D Kahne, SW Kahne, M Adachi, E Doud, S Fuse, X Lin, Y Zhang, ... US Patent 8,604,004, 2013 | 14 | 2013 |
The kidney releases a nonpolymerizing form of uromodulin in the urine and circulation that retains the external hydrophobic patch domain R Micanovic, KA LaFavers, KR Patidar, MS Ghabril, EH Doud, AL Mosley, ... American Journal of Physiology-Renal Physiology 322 (4), F403-F418, 2022 | 13 | 2022 |
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status" LM LaFave, W Béguelin, R Koche, M Teater, B Spitzer, A Chramiec, ... Nature medicine 22 (6), 578-579, 2016 | 11 | 2016 |