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Brian Santich, PhD
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A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency
Q Zhou, GS Lee, J Brady, S Datta, M Katan, A Sheikh, MS Martins, ...
The American Journal of Human Genetics 91 (4), 713-720, 2012
3812012
Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals
L Kardava, S Moir, N Shah, W Wang, R Wilson, CM Buckner, BH Santich, ...
The Journal of clinical investigation 124 (7), 3252-3262, 2014
1452014
Protection from secondary dengue virus infection in a mouse model reveals the role of serotype cross-reactive B and T cells
S Zompi, BH Santich, PR Beatty, E Harris
The Journal of Immunology 188 (1), 404-416, 2012
1192012
Reversible reprogramming of circulating memory T follicular helper cell function during chronic HIV infection
R Cubas, J Van Grevenynghe, S Wills, L Kardava, BH Santich, ...
The Journal of Immunology 195 (12), 5625-5636, 2015
802015
Interdomain spacing and spatial configuration drive the potency of IgG-[L]-scFv T cell bispecific antibodies
BH Santich, JA Park, H Tran, HF Guo, M Huse, NKV Cheung
Science translational medicine 12 (534), eaax1315, 2020
622020
Impaired B cell immunity in acute myeloid leukemia patients after chemotherapy
M Goswami, G Prince, A Biancotto, S Moir, L Kardava, BH Santich, ...
Journal of translational medicine 15, 1-16, 2017
482017
TCR-mimic bispecific antibodies targeting LMP2A show potent activity against EBV malignancies
M Ahmed, A Lopez-Albaitero, D Pankov, BH Santich, H Liu, S Yan, ...
JCI insight 3 (4), 2018
382018
Successful engineering of a highly potent single-chain variable-fragment (scFv) bispecific antibody to target disialoganglioside (GD2) positive tumors
M Cheng, BH Santich, H Xu, M Ahmed, M Huse, NKV Cheung
Oncoimmunology 5 (6), e1168557, 2016
372016
Alpha radioimmunotherapy using 225Ac-proteus-DOTA for solid tumors-safety at curative doses
SM Cheal, MR McDevitt, BH Santich, M Patel, G Yang, EK Fung, ...
Theranostics 10 (25), 11359, 2020
332020
Humans with chronic granulomatous disease maintain humoral immunologic memory despite low frequencies of circulating memory B cells
S Moir, SS De Ravin, BH Santich, JY Kim, JG Posada, J Ho, CM Buckner, ...
Blood, The Journal of the American Society of Hematology 120 (24), 4850-4858, 2012
332012
Potent ex vivo armed T cells using recombinant bispecific antibodies for adoptive immunotherapy with reduced cytokine release
JA Park, BH Santich, H Xu, LG Lum, NKV Cheung
Journal for immunotherapy of cancer 9 (5), 2021
292021
Graves’ disease as immune reconstitution disease in HIV-positive patients is associated with naive and primary thymic emigrant CD4+ T-cell recovery
V Sheikh, R Dersimonian, AG Richterman, BO Porter, V Natarajan, ...
Aids 28 (1), 31-39, 2014
252014
CXCR4/IgG-expressing plasma cells are associated with human gastrointestinal tissue inflammation
CM Buckner, S Moir, L Kardava, J Ho, BH Santich, LJY Kim, EK Funk, ...
Journal of allergy and clinical immunology 133 (6), 1676-1685. e5, 2014
242014
A self-assembling and disassembling (SADA) bispecific antibody (BsAb) platform for curative two-step pretargeted radioimmunotherapy
BH Santich, SM Cheal, M Ahmed, MR McDevitt, O Ouerfelli, G Yang, ...
Clinical Cancer Research 27 (2), 532-541, 2021
222021
Bone marrow plasma cells are a primary source of serum HIV-1–specific antibodies in chronically infected individuals
JM Montezuma-Rusca, S Moir, L Kardava, CM Buckner, A Louie, LJY Kim, ...
The Journal of Immunology 194 (6), 2561-2568, 2015
182015
Generation of TCR-like antibodies using phage display
BH Santich, H Liu, C Liu, NKV Cheung
Peptide Antibodies: Methods and Protocols, 191-204, 2015
102015
Intraperitoneal pretargeted radioimmunotherapy for colorectal peritoneal carcinomatosis
CS Chandler, MM Bell, SK Chung, DR Veach, EK Fung, B Punzalan, ...
Molecular cancer therapeutics 21 (1), 125-137, 2022
82022
Engineered cells as a test platform for radiohaptens in pretargeted imaging and radioimmunotherapy applications
MM Dacek, DR Veach, SM Cheal, LM Carter, MR McDevitt, B Punzalan, ...
Bioconjugate chemistry 32 (4), 649-654, 2021
82021
Bispecific Antibodies for T-Cell Based Immunotherapy
BH Santich, NKV Cheung, C Klein
Frontiers in Oncology 10, 628005, 2020
32020
Persistently elevated abnormal B‐cell subpopulations and anti‐core antibodies in patients co‐infected with HIV/HCV who relapse
A Kohli, E Funk, P Burbelo, L Barrett, EG Meissner, B Santich, A Shaffer, ...
Journal of medical virology 87 (4), 544-552, 2015
32015
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Articles 1–20