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Huchen Zhou
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An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site
FL Rock, W Mao, A Yaremchuk, M Tukalo, T Crépin, H Zhou, YK Zhang, ...
science 316 (5832), 1759-1761, 2007
6822007
Discovery of a new boron-containing antifungal agent, 5-fluoro-1, 3-dihydro-1-hydroxy-2, 1-benzoxaborole (AN2690), for the potential treatment of onychomycosis
SJ Baker, YK Zhang, T Akama, A Lau, H Zhou, V Hernandez, W Mao, ...
Journal of medicinal chemistry 49 (15), 4447-4450, 2006
3602006
Pattern recognition of proteins based on an array of functionalized porphyrins
H Zhou, L Baldini, J Hong, AJ Wilson, AD Hamilton
Journal of the American Chemical Society 128 (7), 2421-2425, 2006
2762006
Discovery and structure–activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis
T Akama, SJ Baker, YK Zhang, V Hernandez, H Zhou, V Sanders, ...
Bioorganic & medicinal chemistry letters 19 (8), 2129-2132, 2009
2632009
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells
CX Liu, QQ Yin, HC Zhou, YL Wu, JX Pu, L Xia, W Liu, X Huang, T Jiang, ...
Nature chemical biology 8 (5), 486-493, 2012
2202012
Small molecule targeting Cdc42–intersectin interaction disrupts Golgi organization and suppresses cell motility
A Friesland, Y Zhao, YH Chen, L Wang, H Zhou, Q Lu
Proceedings of the National Academy of Sciences 110 (4), 1261-1266, 2013
1822013
Synthesis of biologically active boron-containing compounds
F Yang, M Zhu, J Zhang, H Zhou
MedChemComm 9 (2), 201-211, 2018
1182018
Azobenzene-based small molecular photoswitches for protein modulation
M Zhu, H Zhou
Organic & biomolecular chemistry 16 (44), 8434-8445, 2018
1112018
Boron-containing small molecules
SJ Baker, T Akama, VS Hernandez, KM Hold, KR Maples, JJ Plattner, ...
US Patent 7,767,657, 2010
111*2010
Boron-containing small molecules as anti-inflammatory agents
SJ Baker, V Sanders, T Akama, C Bellinger-Kawahara, Y Freund, ...
US Patent 8,168,614, 2012
1102012
Design, Synthesis, and Structure−Activity Relationship of Trypanosoma brucei Leucyl-tRNA Synthetase Inhibitors as Antitrypanosomal Agents
D Ding, Q Meng, G Gao, Y Zhao, Q Wang, B Nare, R Jacobs, F Rock, ...
Journal of medicinal chemistry 54 (5), 1276-1287, 2011
1042011
Signaling through Rho GTPase pathway as viable drug target
Q Lu, FM Longo, H Zhou, SM Massa, YH Chen
Current medicinal chemistry 16 (11), 1355-1365, 2009
1042009
Discovery of novel benzoxaborole-based potent antitrypanosomal agents
D Ding, Y Zhao, Q Meng, D Xie, B Nare, D Chen, CJ Bacchi, N Yarlett, ...
ACS medicinal chemistry letters 1 (4), 165-169, 2010
1022010
Chalcone–benzoxaborole hybrid molecules as potent antitrypanosomal agents
Z Qiao, Q Wang, F Zhang, Z Wang, T Bowling, B Nare, RT Jacobs, ...
Journal of Medicinal Chemistry 55 (7), 3553-3557, 2012
1002012
Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H
W Chen, T Huang, X He, Q Meng, D You, L Bai, J Li, M Wu, R Li, Z Xie, ...
Journal of biological chemistry 284 (16), 10627-10638, 2009
1002009
Functional characterization of three mouse formyl peptide receptors
HQ He, D Liao, ZG Wang, ZL Wang, HC Zhou, MW Wang, DY Richard
Molecular pharmacology 83 (2), 389-398, 2013
922013
Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase
QH Hu, RJ Liu, ZP Fang, J Zhang, YY Ding, M Tan, M Wang, W Pan, ...
Scientific reports 3 (1), 2475, 2013
872013
Structure–activity studies on a library of potent calix [4] arene-based PDGF antagonists that inhibit PDGF-stimulated PDGFR tyrosine phosphorylation
H Zhou, D Wang, L Baldini, E Ennis, R Jain, A Carie, SM Sebti, ...
Organic & biomolecular chemistry 4 (12), 2376-2386, 2006
752006
Advances in the development ubiquitin-specific peptidase (USP) inhibitors
S Chen, Y Liu, H Zhou
International journal of molecular sciences 22 (9), 4546, 2021
702021
Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1, 3-dihydro-1-hydroxy-2, 1-benzoxaboroles
YK Zhang, JJ Plattner, YR Freund, EE Easom, Y Zhou, L Ye, H Zhou, ...
Bioorganic & medicinal chemistry letters 22 (3), 1299-1307, 2012
592012
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