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Delfina Larrea
Delfina Larrea
Associate Research scientist
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
Increased localization of APP‐C99 in mitochondria‐associated ER membranes causes mitochondrial dysfunction in Alzheimer disease
M Pera, D Larrea, C Guardia‐Laguarta, J Montesinos, KR Velasco, ...
The EMBO journal 36 (22), 3356-3371, 2017
1922017
MFN2 mutations in Charcot–Marie–Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics
D Larrea, M Pera, A Gonnelli, R Quintana–Cabrera, HO Akman, ...
Human molecular genetics 28 (11), 1782-1800, 2019
852019
The Alzheimer's disease‐associated C99 fragment of APP regulates cellular cholesterol trafficking
J Montesinos, M Pera, D Larrea, C Guardia‐Laguarta, RR Agrawal, ...
The EMBO journal 39 (20), e103791, 2020
802020
Functional dissection of the conjugative coupling protein TrwB
HD De Paz, D Larrea, S Zunzunegui, C Dehio, F de la Cruz, M Llosa
Journal of bacteriology 192 (11), 2655-2669, 2010
542010
PPARγ deacetylation dissociates thiazolidinedione’s metabolic benefits from its adverse effects
MJ Kraakman, Q Liu, J Postigo-Fernandez, R Ji, N Kon, D Larrea, ...
The Journal of Clinical Investigation 128 (6), 2600-2612, 2018
432018
APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice
E Area-Gomez, D Larrea, M Pera, RR Agrawal, DN Guilfoyle, L Pirhaji, ...
Scientific Reports 10 (1), 4277, 2020
392020
A translocation motif in relaxase TrwC specifically affects recruitment by its conjugative type IV secretion system
A Alperi, D Larrea, E Fernández-González, C Dehio, EL Zechner, M Llosa
Journal of bacteriology 195 (22), 4999-5006, 2013
392013
Lipidomics study of plasma from patients suggest that ALS and PLS are part of a continuum of motor neuron disorders
E Area-Gomez, D Larrea, T Yun, Y Xu, J Hupf, F Zandkarimi, RB Chan, ...
Scientific reports 11 (1), 13562, 2021
362021
Role of E-cadherin in epithelial architecture maintenance
MF Izaguirre, D Larrea, JF Adur, JE Diaz-Zamboni, NB Vicente, ...
Cell communication & adhesion 17 (1), 1-12, 2010
322010
Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure
J Fan, W Du, JY Kim-Muller, J Son, T Kuo, D Larrea, C Garcia, T Kitamoto, ...
Molecular metabolism 34, 97-111, 2020
262020
The silence of the fats: A MAM’s story about Alzheimer
RR Agrawal, J Montesinos, D Larrea, E Area-Gomez, M Pera
Neurobiology of Disease 145, 105062, 2020
252020
Structural independence of conjugative coupling protein TrwB from its type IV secretion machinery
D Larrea, HD De Paz, I Arechaga, F de la Cruz, M Llosa
Plasmid 70 (1), 146-153, 2013
162013
MAM and C99, key players in the pathogenesis of Alzheimer’s disease
M Pera, J Montesinos, D Larrea, RR Agrawal, KR Velasco, ...
International Review of Neurobiology 154, 235-278, 2020
142020
Assessing mitochondrial respiratory bioenergetics in whole cells and isolated organelles by microplate respirometry
RR Agrawal, KA Tamucci, M Pera, D Larrea
Methods in Cell Biology 155, 157-180, 2020
72020
Substrate translocation involves specific lysine residues of the central channel of the conjugative coupling protein TrwB
D Larrea, HD De Paz, I Matilla, DL Guzmán-Herrador, G Lasso, ...
Molecular genetics and genomics 292 (5), 1037-1049, 2017
62017
Alzheimer’s-associated upregulation of mitochondria-associated ER membranes after traumatic brain injury
RR Agrawal, D Larrea, Y Xu, L Shi, H Zirpoli, LG Cummins, V Emmanuele, ...
Cellular and Molecular Neurobiology 43 (5), 2219-2241, 2023
32023
The C99 fragment of APP regulates cholesterol trafficking: Molecular and cell biology/APP/Abeta/amyloid
J Montesinos, M Pera, D Larrea, C Guardia‐Laguarta, E Area‐Gomez
Alzheimer's & Dementia 16, e038479, 2020
12020
APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice
T Nuriel, D Larrea, DN Guilfoyle, L Pirhaji, K Shannon, H Arain, A Ashok, ...
bioRxiv, 482422, 2018
12018
La interfase molecular entre los sistemas de secreción tipo IV y sus sustratos
D Larrea
12013
MFN2-dependent recruitment of ATAT1 coordinates mitochondria motility with alpha-tubulin acetylation and is disrupted in CMT2A
A Kumar, D Larrea, ME Pero, P Infante, M Conenna, GJ Shin, WB Grueber, ...
bioRxiv, 2023.03. 15.532838, 2023
2023
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