| Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study M Hokama, S Oka, J Leon, T Ninomiya, H Honda, K Sasaki, T Iwaki, ... Cerebral cortex 24 (9), 2476-2488, 2014 | 327 | 2014 |
| Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation E Castillo, J Leon, G Mazzei, N Abolhassani, N Haruyama, T Saito, ... Scientific reports 7 (1), 17762, 2017 | 146 | 2017 |
| Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain N Abolhassani, J Leon, Z Sheng, S Oka, H Hamasaki, T Iwaki, ... Mechanisms of ageing and development 161, 95-104, 2017 | 139 | 2017 |
| Peripheral elevation of a klotho fragment enhances brain function and resilience in young, aging, and α-synuclein transgenic mice J Leon, AJ Moreno, BI Garay, RJ Chalkley, AL Burlingame, D Wang, ... Cell reports 20 (6), 1360-1371, 2017 | 116 | 2017 |
| 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions J Leon, K Sakumi, E Castillo, Z Sheng, S Oka, Y Nakabeppu Scientific reports 6 (1), 22086, 2016 | 94 | 2016 |
| Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer’s disease S Oka, J Leon, K Sakumi, T Ide, D Kang, FM LaFerla, Y Nakabeppu Scientific reports 6 (1), 37889, 2016 | 67 | 2016 |
| MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death S Oka, J Leon, D Tsuchimoto, K Sakumi, Y Nakabeppu Oncogenesis 3 (10), e121-e121, 2014 | 57 | 2014 |
| Efecto Genotóxico del Dicromato de Potasio EnEritrocitos de sangre periférica de OreochromisNiloticus (Tilapia) Z Prieto, J León-Incio, C Quijano-Jara, R Fernández, E Polo-Benites, ... Revista Peruana de Medicina Experimental y Salud Pública 25 (1), 51-58, 2008 | 35 | 2008 |
| MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis S Oka, J Leon, K Sakumi, N Abolhassani, Z Sheng, D Tsuchimoto, ... Scientific reports 11 (1), 5819, 2021 | 25 | 2021 |
| KL1 domain of longevity factor klotho mimics the metabolome of cognitive stimulation and enhances cognition in young and aging mice S Gupta, AJ Moreno, D Wang, J Leon, C Chen, O Hahn, Y Poon, ... Journal of Neuroscience 42 (19), 4016-4025, 2022 | 14 | 2022 |
| YY super males have better spermatic quality than XY males in red tilapia Oreochromis niloticus D Salirrosas, J Leon, M Arqueros-Avalos, L Sanchez-Tuesta, F Rabanal, ... Scientia Agropecuaria 8 (4), 349-355, 2017 | 11 | 2017 |
| MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death S Oka, J Leon, D Tsuchimoto, K Sakumi, Y Nakabeppu Oncogenesis 4 (2), e142, 2015 | 9 | 2015 |
| A single-cell atlas of transcribed cis-regulatory elements in the human genome J Moody, T Kouno, M Kojima, I Koya, J Leon, A Suzuki, A Hasegawa, ... bioRxiv, 2023.11. 13.566791, 2023 | 1 | 2023 |
| Clinical validation of RCSMS: A rapid and sensitive CRISPR-Cas12a test for the molecular detection of SARS-CoV-2 from saliva J Abugattas-Núñez del Prado, A Quintana Reyes, J Leon, ... Plos one 19 (3), e0290466, 2024 | | 2024 |
| Learned morphological features guide cell type assignment of deconvolved spatial transcriptomics E Chelebian, C Avenel, J Leon, CC Hon, C Wahlby Medical Imaging with Deep Learning, 2024 | | 2024 |
Yusaku NakabeppuDivision of Neurofunctional Genomics, Medical Institute of Bioregulation, Kyushu UniversityVerified email at bioreg.kyushu-u.ac.jp
