Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13149* | 2021 |
Gene–stress–epigenetic regulation of FKBP5: clinical and translational implications AS Zannas, T Wiechmann, NC Gassen, EB Binder Neuropsychopharmacology 41 (1), 261-274, 2016 | 530 | 2016 |
Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2 M Hoffmann, K Mösbauer, H Hofmann-Winkler, A Kaul, H Kleine-Weber, ... Nature 585 (7826), 588-590, 2020 | 445 | 2020 |
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection NC Gassen, D Niemeyer, D Muth, VM Corman, S Martinelli, A Gassen, ... Nature communications 10 (1), 5770, 2019 | 343 | 2019 |
FK506 binding protein 5 shapes stress responsiveness: modulation of neuroendocrine reactivity and coping behavior C Touma, NC Gassen, L Herrmann, J Cheung-Flynn, DR Büll, IA Ionescu, ... Biological psychiatry 70 (10), 928-936, 2011 | 291 | 2011 |
Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk AS Zannas, M Jia, K Hafner, J Baumert, T Wiechmann, JC Pape, J Arloth, ... Proceedings of the National Academy of Sciences 116 (23), 11370-11379, 2019 | 225 | 2019 |
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals NC Gassen, J Papies, T Bajaj, J Emanuel, F Dethloff, RL Chua, J Trimpert, ... Nature communications 12 (1), 3818, 2021 | 200 | 2021 |
Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans NC Gassen, J Hartmann, J Zschocke, J Stepan, K Hafner, A Zellner, ... PLoS medicine 11 (11), e1001755, 2014 | 166 | 2014 |
Analysis of SARS-CoV-2-controlled autophagy reveals spermidine, MK-2206, and niclosamide as putative antiviral therapeutics NC Gassen, J Papies, T Bajaj, F Dethloff, J Emanuel, K Weckmann, ... BioRxiv, 2020.04. 15.997254, 2020 | 151 | 2020 |
The FKBP51 glucocorticoid receptor co-chaperone: regulation, function, and implications in health and disease GR Fries, NC Gassen, T Rein International journal of molecular sciences 18 (12), 2614, 2017 | 148 | 2017 |
Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function G Balsevich, AS Häusl, CW Meyer, S Karamihalev, X Feng, ML Pöhlmann, ... Nature communications 8 (1), 1725, 2017 | 118 | 2017 |
Life stress, glucocorticoid signaling, and the aging epigenome: Implications for aging-related diseases NC Gassen, GP Chrousos, EB Binder, AS Zannas Neuroscience & Biobehavioral Reviews 74, 356-365, 2017 | 118 | 2017 |
Hypothalamic-pituitary-adrenal axis dysfunction and illness progression in bipolar disorder GR Fries, MP Vasconcelos-Moreno, C Gubert, BTMQ Santos, J Sartori, ... International Journal of Neuropsychopharmacology 18 (1), pyu043, 2015 | 110 | 2015 |
Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine NC Gassen, GR Fries, AS Zannas, J Hartmann, J Zschocke, K Hafner, ... Science signaling 8 (404), ra119-ra119, 2015 | 109 | 2015 |
FKBP5/FKBP51 enhances autophagy to synergize with antidepressant action NC Gassen, J Hartmann, MV Schmidt, T Rein Autophagy 11 (3), 578-580, 2015 | 92 | 2015 |
Prefrontal cortex corticotropin-releasing factor receptor 1 conveys acute stress-induced executive dysfunction A Uribe-Mariño, NC Gassen, MF Wiesbeck, G Balsevich, S Santarelli, ... Biological psychiatry 80 (10), 743-753, 2016 | 87 | 2016 |
Is there a role of autophagy in depression and antidepressant action? NC Gassen, T Rein Frontiers in Psychiatry 10, 424991, 2019 | 84 | 2019 |
Molecular evidence of synaptic pathology in the CA1 region in schizophrenia N Matosin, F Fernandez-Enright, JS Lum, M Engel, JL Andrews, ... npj Schizophrenia 2 (1), 1-8, 2016 | 76 | 2016 |
FKBP51 inhibits GSK3β and augments the effects of distinct psychotropic medications NC Gassen, J Hartmann, AS Zannas, A Kretzschmar, J Zschocke, ... Molecular psychiatry 21 (2), 277-289, 2016 | 73 | 2016 |
Differential impact of tetratricopeptide repeat proteins on the steroid hormone receptors JP Schulke, GM Wochnik, I Lang-Rollin, NC Gassen, RT Knapp, ... PloS one 5 (7), e11717-e11717, 2010 | 73 | 2010 |