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Maria Jose Camarasa
Maria Jose Camarasa
Profesor de investigacion, CSIC
Verified email at iqm.csic.es
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1, 2, 3-Triazole-[2, 5-Bis-O-(tert-butyldimethylsilyl)-. beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'', 2''-oxathiole 2'', 2''-dioxide)(TSAO) Analogs: Synthesis and Anti …
R Alvarez, S Velazquez, A San-Felix, S Aquaro, ED Clercq, CF Perno, ...
Journal of medicinal chemistry 37 (24), 4185-4194, 1994
10181994
Regiospecific Synthesis and Anti-Human Immunodeficiency Virus Activity of Novel 5-Substituted N-Alkylcarbamoyl and N,N-Dialkyl Carbamoyl 1,2,3-Triazole …
S Velazquez, R Alvarez, C Perez, F Gago, E De Clercq, J Balzarini, ...
Antiviral Chemistry and Chemotherapy 9 (6), 481-489, 1998
2821998
2', 5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'', 2''-oxathiole-2'', 2'-dioxide) pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human …
J Balzarini, MJ Perez-Perez, A San-Felix, D Schols, CF Perno, ...
Proceedings of the National Academy of Sciences 89 (10), 4392-4396, 1992
2511992
HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase
J Balzarini, A Karlsson, MJ Perez-Perez, L Vrang, J Walbers, H Zhang, ...
Virology 192 (1), 246-253, 1993
2011993
3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors: synthesis and antiviral activity of [2', 5'-bis-O-(tert-butyldimethylsilyl)-. beta …
MJ Camarasa, MJ Perez-Perez, A San-Felix, J Balzarini, E De Clercq
Journal of Medicinal Chemistry 35 (15), 2721-2727, 1992
1661992
Kinetics of inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by the novel HIV-1-specific nucleoside analogue [2', 5'-bis-O-(tert …
J Balzarini, MJ Pérez-Pérez, A San-Felix, MJ Camarasa, IC Bathurst, ...
Journal of Biological Chemistry 267 (17), 11831-11838, 1992
1441992
Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does …
J Balzarini, A Karlsson, MJ Pérez-Pérez, MJ Camarasa, WG Tarpley, ...
Journal of virology 67 (9), 5353-5359, 1993
1311993
TSAO analogs. Stereospecific synthesis and anti-HIV-1 activity of 1-[2', 5'-bis-O-(tert-butyldimethylsilyl)-. beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'', 2''-oxathiole …
MJ Perez-Perez, A San-Felix, J Balzarini, E De Clercq, MJ Camarasa
Journal of medicinal chemistry 35 (16), 2988-2995, 1992
1211992
Design, Synthesis, and Enzymatic Evaluation of Multisubstrate Analogue Inhibitors of Escherichia coli Thymidine Phosphorylase
A Esteban-Gamboa, J Balzarini, R Esnouf, E De Clercq, MJ Camarasa, ...
Journal of medicinal chemistry 43 (5), 971-983, 2000
1142000
Resistance of HIV-1 reverse transcriptase against [2', 5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5 “-(4”-amino-1 “, 2”-oxathiole-2 “, 2”-dioxide)](TSAO) derivatives is …
H Jonckheere, JM Taymans, J Balzarini, S Velazquez, MJ Camarasa, ...
Journal of Biological Chemistry 269 (41), 25255-25258, 1994
991994
7-Deazaxanthine, a novel prototype inhibitor of thymidine phosphorylase
J Balzarini, AE Gamboa, R Esnouf, S Liekens, J Neyts, E De Clercq, ...
FEBS letters 438 (1-2), 91-95, 1998
941998
Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus
C McGuigan, RN Pathirana, M Migliore, R Adak, G Luoni, AT Jones, ...
Journal of antimicrobial chemotherapy 60 (6), 1316-1330, 2007
932007
Human Immunodeficiency Virus Type 1 Reverse Transcriptase Dimer Destabilization by 1-{Spiro [4 ‘‘-amino-2 ‘‘, 2 ‘‘-dioxo-1 ‘‘, 2 ‘‘-oxathiole-5 ‘‘, 3 ‘-[2 ‘, 5 ‘-bis-O-(tert …
N Sluis-Cremer, GI Dmitrienko, J Balzarini, MJ Camarasa, MA Parniak
Biochemistry 39 (6), 1427-1433, 2000
912000
Dimerization inhibitors of HIV-1 reverse transcriptase, protease and integrase: a single mode of inhibition for the three HIV enzymes?
MJ Camarasa, S Velázquez, A San-Félix, MJ Pérez-Pérez, F Gago
Antiviral research 71 (2-3), 260-267, 2006
882006
Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus
J Balzarini, A Karlsson, MJ Pérez-Pérez, MJ Camarasa, E De Clercq
Virology 196 (2), 576-585, 1993
861993
Identification of a Putative Binding Site for [2‘,5‘-Bis-O-(tert-butyldimethylsilyl)-β-d-ribofuranosyl]-3‘-spiro-5‘ ‘-(4‘ ‘-amino-1‘ ‘,2‘ ‘-oxathiole-2‘ ‘,2‘ ‘-dioxide …
F Rodríguez-Barrios, C Pérez, E Lobatón, S Velázquez, C Chamorro, ...
Journal of Medicinal Chemistry 44 (12), 1853-1865, 2001
822001
Crystal Structure of tert-Butyldimethylsilyl-spiroaminooxathioledioxide-thymine (TSAO-T) in Complex with HIV-1 Reverse Transcriptase (RT) Redefines the Elastic …
K Das, JD Bauman, AS Rim, C Dharia, AD Clark Jr, MJ Camarasa, ...
Journal of medicinal chemistry 54 (8), 2727-2737, 2011
802011
Identification of [1,2,3]Triazolo[4,5-d]pyrimidin-7(6H)-ones as Novel Inhibitors of Chikungunya Virus Replication
A Gigante, MD Canela, L Delang, EM Priego, MJ Camarasa, G Querat, ...
Journal of Medicinal Chemistry 57 (10), 4000-4008, 2014
792014
The nucleoside derivative 5′-O-trityl-inosine (KIN59) suppresses thymidine phosphorylase-triggered angiogenesis via a noncompetitive mechanism of action
S Liekens, AI Hernández, D Ribatti, E De Clercq, MJ Camarasa, ...
Journal of Biological Chemistry 279 (28), 29598-29605, 2004
732004
Pyrido[2,1-f]purine-2,4-dione Derivatives as a Novel Class of Highly Potent Human A3 Adenosine Receptor Antagonists
EM Priego, J von Frijtag Drabbe Kuenzel, AP IJzerman, MJ Camarasa, ...
Journal of medicinal chemistry 45 (16), 3337-3344, 2002
732002
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