Use of the light/dark test for anxiety in adult and adolescent male rats AE Arrant, NL Schramm-Sapyta, CM Kuhn Behavioural brain research 256, 119-127, 2013 | 178 | 2013 |
Progranulin gene therapy improves lysosomal dysfunction and microglial pathology associated with frontotemporal dementia and neuronal ceroid lipofuscinosis AE Arrant, VC Onyilo, DE Unger, ED Roberson Journal of Neuroscience 38 (9), 2341-2358, 2018 | 127 | 2018 |
Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD ME Ward, A Taubes, R Chen, BL Miller, CF Sephton, JM Gelfand, ... Journal of Experimental Medicine 211 (10), 1937-1945, 2014 | 113 | 2014 |
Effects of acute tryptophan depletion on brain serotonin function and concentrations of dopamine and norepinephrine in C57BL/6J and BALB/cJ mice CS Biskup, CL Sánchez, A Arrant, AED Van Swearingen, C Kuhn, ... PLoS One 7 (5), e35916, 2012 | 85 | 2012 |
Rho kinase inhibition as a therapeutic for progressive supranuclear palsy and corticobasal degeneration EG Gentry, BW Henderson, AE Arrant, M Gearing, Y Feng, NC Riddle, ... Journal of Neuroscience 36 (4), 1316-1323, 2016 | 83 | 2016 |
Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans CP González-Hunt, MCK Leung, RK Bodhicharla, MG McKeever, ... PloS one 9 (12), e114459, 2014 | 78 | 2014 |
Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia AE Arrant, AJ Filiano, DE Unger, AH Young, ED Roberson Brain 140 (5), 1447-1465, 2017 | 73 | 2017 |
Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations AE Arrant, JR Roth, NR Boyle, SN Kashyap, MQ Hoffmann, CF Murchison, ... Acta Neuropathologica Communications 7 (1), 1-17, 2019 | 54 | 2019 |
Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions LE Stoyka, AE Arrant, DR Thrasher, DL Russell, J Freire, CL Mahoney, ... Neurobiology of Disease, 104708, 2019 | 53 | 2019 |
Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test AE Arrant, AJ Filiano, BA Warmus, AM Hall, ED Roberson Genes, Brain and Behavior 15 (6), 588-603, 2016 | 42 | 2016 |
Dopamine uptake inhibitors but not dopamine releasers induce greater increases in motor behavior and extracellular dopamine in adolescent rats than in adult male rats QD Walker, SE Morris, AE Arrant, JM Nagel, S Parylak, G Zhou, JM Caster, ... Journal of Pharmacology and Experimental Therapeutics 335 (1), 124-132, 2010 | 40 | 2010 |
Adolescent male rats are less sensitive than adults to the anxiogenic and serotonin-releasing effects of fenfluramine AE Arrant, H Jemal, CM Kuhn Neuropharmacology 65, 213-222, 2013 | 34 | 2013 |
Individual differences in psychostimulant responses of female rats are associated with ovarian hormones and dopamine neuroanatomy QD Walker, ML Johnson, AED Van Swearingen, AE Arrant, JM Caster, ... Neuropharmacology 62 (7), 2267-2277, 2012 | 29 | 2012 |
Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency AE Arrant, AM Nicholson, X Zhou, R Rademakers, ED Roberson Molecular neurodegeneration 13 (1), 32, 2018 | 28 | 2018 |
Simplified dietary acute tryptophan depletion: effects of a novel amino acid mixture on the neurochemistry of C57BL/6J mice CL Sánchez, AED Van Swearingen, AE Arrant, CS Biskup, CM Kuhn, ... Food & nutrition research 59 (1), 27424, 2015 | 19 | 2015 |
MicroRNA-124 modulates social behavior in frontotemporal dementia AE Arrant, ED Roberson Nature medicine 20 (12), 1381, 2014 | 17 | 2014 |
Dietary manipulation of serotonergic and dopaminergic function in C57BL/6J mice with amino acid depletion mixtures CL Sánchez, AED Van Swearingen, AE Arrant, CM Kuhn, FD Zepf Journal of Neural Transmission 121 (2), 153-162, 2014 | 17 | 2014 |
Delivering progranulin to neuronal lysosomes protects against excitotoxicity SE Davis, JR Roth, Q Aljabi, AR Hakim, KE Savell, JJ Day, AE Arrant Journal of Biological Chemistry 297 (3), 2021 | 16 | 2021 |
Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient mice AE Arrant, AJ Filiano, AR Patel, MQ Hoffmann, NR Boyle, SN Kashyap, ... Neurobiology of disease 124, 152-162, 2019 | 15 | 2019 |
Lower anxiogenic effects of serotonin agonists are associated with lower activation of amygdala and lateral orbital cortex in adolescent male rats AE Arrant, E Coburn, J Jacobsen, CM Kuhn Neuropharmacology 73, 359-367, 2013 | 14 | 2013 |