| Bacterial cGAS-like enzymes synthesize diverse nucleotide signals AT Whiteley, JB Eaglesham, CC de Oliveira Mann, BR Morehouse, ... Nature 567 (7747), 194-199, 2019 | 297 | 2019 |
| Structure of the human cGAS–DNA complex reveals enhanced control of immune surveillance W Zhou, AT Whiteley, CC de Oliveira Mann, BR Morehouse, RP Nowak, ... Cell 174 (2), 300-311. e11, 2018 | 277 | 2018 |
| Glutathione activates virulence gene expression of an intracellular pathogen ML Reniere, AT Whiteley, KL Hamilton, SM John, P Lauer, RG Brennan, ... Nature 517 (7533), 170-173, 2015 | 257 | 2015 |
| Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection CE Witte, AT Whiteley, TP Burke, JD Sauer, DA Portnoy, JJ Woodward MBio 4 (3), 10.1128/mbio. 00282-13, 2013 | 204 | 2013 |
| The PAMP c-di-AMP is essential for Listeria monocytogenes growth in rich but not minimal media due to a toxic increase in (p) ppGpp AT Whiteley, AJ Pollock, DA Portnoy Cell host & microbe 17 (6), 788-798, 2015 | 156 | 2015 |
| Structure and mechanism of a cyclic trinucleotide-activated bacterial endonuclease mediating bacteriophage immunity RK Lau, Q Ye, EA Birkholz, KR Berg, L Patel, IT Mathews, JD Watrous, ... Molecular cell 77 (4), 723-733. e6, 2020 | 155 | 2020 |
| CBASS immunity uses CARF-related effectors to sense 3′–5′-and 2′–5′-linked cyclic oligonucleotide signals and protect bacteria from phage infection B Lowey, AT Whiteley, AFA Keszei, BR Morehouse, IT Mathews, ... Cell 182 (1), 38-49. e17, 2020 | 145 | 2020 |
| RNA-based fluorescent biosensors for live cell imaging of second messenger cyclic di-AMP CA Kellenberger, C Chen, AT Whiteley, DA Portnoy, MC Hammond Journal of the American Chemical Society 137 (20), 6432-6435, 2015 | 131 | 2015 |
| c‐di‐AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation AT Whiteley, NE Garelis, BN Peterson, PH Choi, L Tong, JJ Woodward, ... Molecular microbiology 104 (2), 212-233, 2017 | 120 | 2017 |
| Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy G Mitchell, MI Cheng, C Chen, BN Nguyen, AT Whiteley, S Kianian, ... Proceedings of the National Academy of Sciences 115 (2), E210-E217, 2018 | 89 | 2018 |
| An In Vivo Selection Identifies Listeria monocytogenes Genes Required to Sense the Intracellular Environment and Activate Virulence Factor Expression ML Reniere, AT Whiteley, DA Portnoy PLoS pathogens 12 (7), e1005741, 2016 | 79 | 2016 |
| Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment JL Portman, SB Dubensky, BN Peterson, AT Whiteley, DA Portnoy MBio 8 (5), 10.1128/mbio. 01595-17, 2017 | 46 | 2017 |
| Bacterial NLR-related proteins protect against phage EM Kibby, AN Conte, AM Burroughs, TA Nagy, JA Vargas, LA Whalen, ... Cell 186 (11), 2410-2424. e18, 2023 | 44 | 2023 |
| An E1–E2 fusion protein primes antiviral immune signalling in bacteria HE Ledvina, Q Ye, Y Gu, AE Sullivan, Y Quan, RK Lau, H Zhou, ... Nature 616 (7956), 319-325, 2023 | 35 | 2023 |
| (p) ppGpp and c-di-AMP homeostasis is controlled by CbpB in Listeria monocytogenes BN Peterson, MKM Young, S Luo, J Wang, AT Whiteley, JJ Woodward, ... Mbio 11 (4), 10.1128/mbio. 01625-20, 2020 | 33 | 2020 |
| A redox-responsive transcription factor is critical for pathogenesis and aerobic growth of Listeria monocytogenes AT Whiteley, BR Ruhland, MB Edrozo, ML Reniere Infection and immunity 85 (5), 10.1128/iai. 00978-16, 2017 | 33 | 2017 |
| Molecular basis of CD-NTase nucleotide selection in CBASS anti-phage defense AA Govande, B Duncan-Lowey, JB Eaglesham, AT Whiteley, ... Cell Reports 35 (9), 2021 | 31 | 2021 |
| Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling D Chang, AT Whiteley, K Bugda Gwilt, WI Lencer, JJ Mekalanos, ... Proceedings of the National Academy of Sciences 117 (44), 27502-27508, 2020 | 19 | 2020 |
| Activation of the Listeria monocytogenes virulence program by a reducing environment. mBio 8: e01595-17 JL Portman, SB Dubensky, BN Peterson, AT Whiteley, DA Portnoy | 16 | 2017 |
| cGASylation by a bacterial E1-E2 fusion protein primes antiviral immune signaling HE Ledvina, Q Ye, Y Gu, Y Quan, RK Lau, H Zhou, KD Corbett, ... BioRxiv, 2022.03. 31.486616, 2022 | 11 | 2022 |
