Delineating the role of cooperativity in the design of potent PROTACs for BTK A Zorba, C Nguyen, Y Xu, J Starr, K Borzilleri, J Smith, H Zhu, KA Farley, ... Proceedings of the National Academy of Sciences 115 (31), E7285-E7292, 2018 | 320 | 2018 |
Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes J Schiemer, R Horst, Y Meng, JI Montgomery, Y Xu, X Feng, K Borzilleri, ... Nature Chemical Biology 17 (2), 152-160, 2021 | 69 | 2021 |
Thermodynamic analysis of protein folding and stability using a tryptophan modification protocol Y Xu, EC Strickland, MC Fitzgerald Analytical chemistry 86 (14), 7041-7048, 2014 | 43 | 2014 |
Sites associated with Kalydeco binding on human cystic fibrosis transmembrane conductance regulator revealed by hydrogen/deuterium exchange LJ Byrnes, Y Xu, X Qiu, JD Hall, GM West Scientific Reports 8 (1), 4664, 2018 | 32 | 2018 |
Thermodynamic Analysis of the Geldanamycin–Hsp90 Interaction in a Whole Cell Lysate Using a Mass Spectrometry-Based Proteomics Approach Y Xu, MAG Wallace, MC Fitzgerald Journal of The American Society for Mass Spectrometry 27 (10), 1670-1676, 2016 | 29 | 2016 |
Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins? RN Ogburn, TA Randall, Y Xu, JH Roberts, B Mebrahtu, JM Karnuta, ... Journal of Allergy and Clinical Immunology 139 (3), 1030-1032. e1, 2017 | 22 | 2017 |
A comparison of two stability proteomics methods for drug target identification in OnePot 2D format Y Xu, GM West, M Abdelmessih, MD Troutman, RA Everley ACS Chemical Biology 16 (8), 1445-1455, 2021 | 18 | 2021 |
Thiomethyltetrazines Are Reversible Covalent Cysteine Warheads Whose Dynamic Behavior can be “Switched Off” via Bioorthogonal Chemistry Inside Live Cells AM Tallon, Y Xu, GM West, CW Am Ende, JM Fox Journal of the American Chemical Society 145 (29), 16069-16080, 2023 | 16 | 2023 |
Amphiphilic mesogen‐jacketed liquid crystalline polymers: Design, synthesis, and self‐assembly behaviors H Wu, L Zhang, Y Xu, Z Ma, Z Shen, X Fan, Q Zhou Journal of Polymer Science Part A: Polymer Chemistry 50 (9), 1792-1800, 2012 | 10 | 2012 |
Development and Application of Covalent-Labeling Strategies for the Large-Scale Thermodynamic Analysis of Protein Folding and Ligand Binding Y Xu Duke University, 2016 | | 2016 |