| How directed evolution reshapes the energy landscape in an enzyme to boost catalysis R Otten, RAP Pádua, HA Bunzel, V Nguyen, W Pitsawong, MK Patterson, ... Science 370 (6523), 1442-1446, 2020 | 125 | 2020 |
| Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2 RAP Pádua, Y Sun, I Marko, W Pitsawong, JB Stiller, R Otten, D Kern Nature communications 9 (1), 4507, 2018 | 100 | 2018 |
| A conserved active-site threonine is important for both sugar and flavin oxidations of pyranose 2-oxidase W Pitsawong, J Sucharitakul, M Prongjit, TC Tan, O Spadiut, D Haltrich, ... Journal of biological chemistry 285 (13), 9697-9705, 2010 | 69 | 2010 |
| Understanding the broad substrate repertoire of nitroreductase based on its kinetic mechanism W Pitsawong, JP Hoben, AF Miller Journal of Biological Chemistry 289 (22), 15203-15214, 2014 | 65 | 2014 |
| The transfer of reduced flavin mononucleotide from LuxG oxidoreductase to luciferase occurs via free diffusion R Tinikul, W Pitsawong, J Sucharitakul, S Nijvipakul, DP Ballou, ... Biochemistry 52 (39), 6834-6843, 2013 | 52 | 2013 |
| Predicting multiple conformations via sequence clustering and AlphaFold2 HK Wayment-Steele, A Ojoawo, R Otten, JM Apitz, W Pitsawong, ... Nature 625 (7996), 832-839, 2024 | 44 | 2024 |
| Ancient origins of allosteric activation in a Ser-Thr kinase A Hadzipasic, C Wilson, V Nguyen, N Kern, C Kim, W Pitsawong, J Villali, ... Science 367 (6480), 912-917, 2020 | 44 | 2020 |
| Dynamics of human protein kinase Aurora A linked to drug selectivity W Pitsawong, V Buosi, R Otten, RV Agafonov, A Zorba, N Kern, S Kutter, ... Elife 7, e36656, 2018 | 38 | 2018 |
| Cumulative mechanism of several major imatinib-resistant mutations in Abl kinase M Hoemberger, W Pitsawong, D Kern Proceedings of the National Academy of Sciences 117 (32), 19221-19227, 2020 | 36 | 2020 |
| H-bonding and positive charge at the N (5)/O (4) locus are critical for covalent flavin attachment in Trametes pyranose 2-oxidase TC Tan, W Pitsawong, T Wongnate, O Spadiut, D Haltrich, P Chaiyen, ... Journal of molecular biology 402 (3), 578-594, 2010 | 35 | 2010 |
| Informing efforts to develop nitroreductase for amine production AF Miller, JT Park, KL Ferguson, W Pitsawong, AS Bommarius Molecules 23 (2), 211, 2018 | 32 | 2018 |
| Mechanism-informed refinement reveals altered substrate-binding mode for catalytically competent nitroreductase W Pitsawong, CA Haynes, RL Koder, DW Rodgers, AF Miller Structure 25 (7), 978-987. e4, 2017 | 23 | 2017 |
| Tuning of pKa values activates substrates in flavin-dependent aromatic hydroxylases W Pitsawong, P Chenprakhon, T Dhammaraj, D Medhanavyn, ... Journal of Biological Chemistry 295 (12), 3965-3981, 2020 | 15 | 2020 |
| From primordial clocks to circadian oscillators W Pitsawong, RAP Pádua, T Grant, M Hoemberger, R Otten, N Bradshaw, ... Nature 616 (7955), 183-189, 2023 | 10 | 2023 |
| From primordial clocks to circadian oscillators N Bradshaw, W Pitsawong, R Ap Pádua, T Grant, M Hoemberger, R Otten, ... Nature, 2023 | | 2023 |
| Dynamics of human protein kinases linked to drug selectivity [preprint] D Kern, W Pitsawong, R Otten, RV Agafonov, A Zorba, N Kern, S Kutter, ... | | 2018 |
| BASES FOR BREADTH-INSIGHTS INTO HOW THE MECHANISM AND DYNAMICS OF NITROREDUCTASE CAN EXPLAIN THIS ENZYME'S BROAD SUBSTRATE REPERTOIRE W Pitsawong | | 2014 |
| Investigation on the Role of Threonine 169 in the Reaction Catalyzed by Pyranose 2-oxidase W Pitsawong Mahidol University, 2009 | | 2009 |
| Dynamics of human protein kinases linked to drug selectivity D Kern, W Pitsawong Dynamics 3, 21-2018, 0 | | |
