| The mechanobiology of aging JM Phillip, I Aifuwa, J Walston, D Wirtz Annual review of biomedical engineering 17, 113-141, 2015 | 290 | 2015 |
| Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture N Yusufova, A Kloetgen, M Teater, A Osunsade, JM Camarillo, CR Chin, ... Nature 589 (7841), 299-305, 2021 | 181 | 2021 |
| Inhibition of spleen tyrosine kinase potentiates paclitaxel-induced cytotoxicity in ovarian cancer cells by stabilizing microtubules Y Yu, S Gaillard, JM Phillip, TC Huang, SM Pinto, NG Tessarollo, Z Zhang, ... Cancer cell 28 (1), 82-96, 2015 | 163 | 2015 |
| Clinical and biological subtypes of B-cell lymphoma revealed by microenvironmental signatures N Kotlov, A Bagaev, MV Revuelta, JM Phillip, MT Cacciapuoti, ... Cancer discovery 11 (6), 1468-1489, 2021 | 140 | 2021 |
| Single-cell morphology encodes metastatic potential PH Wu, DM Gilkes, JM Phillip, A Narkar, TWT Cheng, J Marchand, ... Science advances 6 (4), eaaw6938, 2020 | 134 | 2020 |
| Volume regulation and shape bifurcation in the cell nucleus DH Kim, B Li, F Si, JM Phillip, D Wirtz, SX Sun Journal of cell science 128 (18), 3375-3385, 2015 | 129 | 2015 |
| Mutant EZH2 induces a pre-malignant lymphoma niche by reprogramming the immune response W Béguelin, M Teater, C Meydan, KB Hoehn, JM Phillip, AA Soshnev, ... Cancer cell 37 (5), 655-673. e11, 2020 | 116 | 2020 |
| Evolution of cellular morpho-phenotypes in cancer metastasis PH Wu, JM Phillip, SB Khatau, WC Chen, J Stirman, S Rosseel, K Tschudi, ... Scientific reports 5 (1), 18437, 2015 | 105 | 2015 |
| THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors F Cayrol, P Praditsuktavorn, TM Fernando, N Kwiatkowski, R Marullo, ... Nature communications 8 (1), 14290, 2017 | 101 | 2017 |
| MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents MY Shah, E Martinez-Garcia, JM Phillip, AB Chambliss, R Popovic, ... Oncogene 35 (45), 5905-5915, 2016 | 92 | 2016 |
| Biophysical and biomolecular determination of cellular age in humans JM Phillip, PH Wu, DM Gilkes, W Williams, S McGovern, J Daya, J Chen, ... Nature biomedical engineering 1 (7), 0093, 2017 | 86 | 2017 |
| A robust unsupervised machine-learning method to quantify the morphological heterogeneity of cells and nuclei JM Phillip, KS Han, WC Chen, D Wirtz, PH Wu Nature protocols 16 (2), 754-774, 2021 | 81 | 2021 |
| TBL1XR1 mutations drive extranodal lymphoma by inducing a pro-tumorigenic memory fate L Venturutti, M Teater, A Zhai, A Chadburn, L Babiker, D Kim, W Béguelin, ... Cell 182 (2), 297-316. e27, 2020 | 76 | 2020 |
| Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma X Wei, MN Calvo-Vidal, S Chen, G Wu, MV Revuelta, J Sun, J Zhang, ... Cancer research 78 (10), 2747-2759, 2018 | 68 | 2018 |
| Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair Q Guo, JM Phillip, S Majumdar, PH Wu, J Chen, X Calderón-Colón, ... Biomaterials 34 (37), 9365-9372, 2013 | 55 | 2013 |
| Use of the p-values as a size-dependent function to address practical differences when analyzing large datasets E Gómez-de-Mariscal, V Guerrero, A Sneider, H Jayatilaka, JM Phillip, ... Scientific reports 11 (1), 20942, 2021 | 45 | 2021 |
| Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis KM Aw Yong, Y Zeng, D Vindivich, JM Phillip, PH Wu, D Wirtz, ... Journal of cellular physiology 229 (3), 362-373, 2014 | 44 | 2014 |
| Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy T Dalton, E Doubrovina, D Pankov, R Reynolds, H Scholze, A Selvakumar, ... Blood, The Journal of the American Society of Hematology 135 (21), 1870-1881, 2020 | 41 | 2020 |
| Volume regulation and shape bifurcation in the cell nucleus DH Kim, B Li, F Si, JM Phillip, D Wirtz, SX Sun Journal of cell science 129 (2), 457-457, 2016 | 37 | 2016 |
| BCL6 evolved to enable stress tolerance in vertebrates and is broadly required by cancer cells to adapt to stress TM Fernando, R Marullo, B Pera Gresely, JM Phillip, SN Yang, ... Cancer discovery 9 (5), 662-679, 2019 | 34 | 2019 |
Denis WirtzT.H. Smoot Professor of Engineering Science, Pathology, and Oncology; VP Research, Johns HopkinsVerified email at jhu.edu
