The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, etc Aging Cell, 2015 Aug;14(4):644-58, 2015 | 1998* | 2015 |
JAK inhibition alleviates the cellular senescence- associated secretory phenotype and frailty in old age Xu M, Tchkonia T, Ding H, Ogrodnik M, Pirtskhalava T, Whitea T, Johnson K ... PNAS 112 (doi:10.1073/pnas.1515386112), E6301-10, 2015 | 671* | 2015 |
Targeting senescent cells enhances adipogenesis and metabolic function in old age Xu M, Palmer AK, Ding H, Weivoda MM, Pirtskhalava T, White TA, Sepe A ... eLife, eLife 2015;10.7554/eLife.12997, 2015 | 532* | 2015 |
Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment. C Correia C, Lee SH, Meng XW, Vincelette ND, Knorr KL, Ding H, Nowakowski GS ... Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1853 ((7 …, 2015 | 181 | 2015 |
BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma C Correia, PA Schneider, H Dai, A Dogan, MJ Maurer, AK Church, ... Blood, The Journal of the American Society of Hematology 125 (4), 658-667, 2015 | 159 | 2015 |
Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3 C Fu, K Ahmed, H Ding, X Ding, J Lan, Z Yang, Y Miao, Y Zhu, Y Shi, ... Oncogene 24 (35), 5401-5413, 2005 | 130 | 2005 |
Contribution of Bcl-2 phosphorylation to Bak binding and drug resistance Dai H, Ding H, Meng XW, Lee SH, Schneider PA, Kaufmann SH Cancer research 73 (23), 6998-7008, 2013 | 112 | 2013 |
SUMO-1 modification increases human SOD1 stability and aggregation E Fei, N Jia, M Yan, Z Ying, Q Sun, H Wang, T Zhang, X Ma, H Ding, ... Biochemical and biophysical research communications 347 (2), 406-412, 2006 | 108 | 2006 |
Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells Dai H, Ding H, Meng XW, Peterson KL, Schneider PA, Karp JE, Kaufmann SH Genes & Development 2015, 29 (20), 2140-2152, 2015 | 103* | 2015 |
Multi-institutional phase 2 study of the farnesyltransferase inhibitor tipifarnib (R115777) in patients with relapsed and refractory lymphomas TE Witzig, H Tang, INM Micallef, SM Ansell, BK Link, DJ Inwards, ... Blood 2011, 118 (18), 4882-4889, 2011 | 51 | 2011 |
Solution Structure of Human SUMO-3 C47S and Its Binding Surface for Ubc9, H Ding, Y Xu, Q Chen, H Dai, Y Tang, J Wu, Y Shi Biochemistry 44 (8), 2790-2799, 2005 | 46 | 2005 |
Farnesyltransferase inhibitor tipifarnib inhibits Rheb prenylation and stabilizes Bax in acute myelogenous leukemia cells Ding H, McDonald JS, Yun S, Schneider PA, Peterson KL, Flatten KS, Loegering ... Haematologica 2014, 99 (1), 60-69, 2014 | 36 | 2014 |
Selection of Single Chain Fragment Variables with Direct Coating of Aflatoxin B1 to Enzyme-Linked Immunosorbent Assay Plates L Yang, H Ding, Z Gu, J Zhao, H Chen, F Tian, YQ Chen, H Zhang, ... Journal of agricultural and food chemistry 57 (19), 8927-8932, 2009 | 34 | 2009 |
Histone Deacetylase Inhibitors Interrupt HSP90.RasGRP1 and HSP90.CRaf Interactions to Upregulate BIM and Circumvent Drug Resistance in Lymphoma Cells Ding H, Peterson KL,Correia H, Koh B, Schneider PA,Nowakowski GS, Kaufmann SH Leukemia 2017, 31 (7), 1593–1602, 2017 | 32 | 2017 |
Binding model of human coactosin-like protein with filament actin revealed by mutagenesis H Dai, W Huang, J Xu, B Yao, S Xiong, H Ding, Y Tang, H Liu, J Wu, Y Shi Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1764 (11), 1688-1700, 2006 | 26 | 2006 |
Cytotoxicity of farnesyltransferase inhibitors in lymphoid cells mediated by MAPK pathway inhibition and Bim up-regulation Ding H, Hackbarth J, Schneider PA, Peterson KL, Meng XW, Dai H, Witzig TE ... Blood 2011, 118 (18), 4872-4881, 2011 | 25* | 2011 |
Measurement of BH-3 only Protein Tolerance Dai H, Ding H, Peterson KL, Schneider PA, Knorr KL and Kaufmann SH, Cell Death & Differentiation, 2018, 282-293, 2018 | 23 | 2018 |
Effect of CHK1 Inhibition on CPX-351 Cytotoxicity in vitro and ex vivo ND Vincelette, H Ding, AM Huehls, KS Flatten, RL Kelly, MA Kohorst, ... Scientific reports 9 (1), 3617, 2019 | 13 | 2019 |
Structural basis for SUMO‐E2 interaction revealed by a complex model using docking approach in combination with NMR data H Ding, Y Yang, J Zhang, J Wu, H Liu, Y Shi Proteins: Structure, Function, and Bioinformatics 61 (4), 1050-1058, 2005 | 12 | 2005 |
Repurposing ceritinib induces DNA damage and enhances PARP inhibitor responses in high-grade serous ovarian carcinoma A Kanakkanthara, X Hou, TL Ekstrom, V Zanfagnin, AM Huehls, RL Kelly, ... Cancer research 82 (2), 307-319, 2022 | 10 | 2022 |