| PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair T Ochi, AN Blackford, J Coates, S Jhujh, S Mehmood, N Tamura, ... Science 347 (6218), 185-188, 2015 | 366 | 2015 |
| Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells H Dev, TWW Chiang, C Lescale, I de Krijger, AG Martin, D Pilger, ... Nature cell biology 20 (8), 954-965, 2018 | 351 | 2018 |
| Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions W Qian, O Takashi, MV Dijana, VR Carol, YC Dimitri, LB Tom Biochemical Society Transactions 39 (5), 1387-1392, 2011 | 91 | 2011 |
| The spatial organization of non-homologous end joining: from bridging to end joining T Ochi, Q Wu, TL Blundell DNA repair 17, 98-109, 2014 | 89 | 2014 |
| Dissection of DNA double-strand-break repair using novel single-molecule forceps JL Wang, C Duboc, Q Wu, T Ochi, S Liang, SE Tsutakawa, SP Lees-Miller, ... Nature structural & molecular biology 25 (6), 482-487, 2018 | 85 | 2018 |
| Mutations in the NHEJ component XRCC4 cause primordial dwarfism JE Murray, M Van Der Burg, H IJspeert, P Carroll, Q Wu, T Ochi, A Leitch, ... The American Journal of Human Genetics 96 (3), 412-424, 2015 | 85 | 2015 |
| Structure of BRCA1-BRCT/Abraxas complex reveals phosphorylation-dependent BRCT dimerization at DNA damage sites Q Wu, A Paul, D Su, S Mehmood, TK Foo, T Ochi, EL Bunting, B Xia, ... Molecular cell 61 (3), 434-448, 2016 | 75 | 2016 |
| Structural insights into the role of domain flexibility in human DNA ligase IV T Ochi, Q Wu, DY Chirgadze, JG Grossmann, VM Bolanos-Garcia, ... Structure, 2012 | 50 | 2012 |
| Structural biology of DNA repair: spatial organisation of the multicomponent complexes of nonhomologous end joining T Ochi, BL Sibanda, Q Wu, DY Chirgadze, VM Bolanos-Garcia, ... Journal of nucleic acids 2010, 2010 | 46 | 2010 |
| Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif Q Wu, H Jubb, TL Blundell Progress in biophysics and molecular biology 117 (2-3), 143-148, 2015 | 45 | 2015 |
| The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage R Nishi, PWG Wijnhoven, Y Kimura, M Matsui, R Konietzny, Q Wu, ... Scientific reports 8 (1), 17891, 2018 | 33 | 2018 |
| Spatial and temporal organization of multi-protein assemblies: achieving sensitive control in information-rich cell-regulatory systems VM Bolanos-Garcia, Q Wu, T Ochi, DY Chirgadze, BL Sibanda, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2012 | 33 | 2012 |
| Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways Q Wu, S Liang, T Ochi, DY Chirgadze, JT Huiskonen, TL Blundell Progress in Biophysics and Molecular Biology 147, 26-32, 2019 | 20 | 2019 |
| Structural mechanism of DNA-end synapsis in the non-homologous end joining pathway for repairing double-strand breaks: Bridge over troubled ends Q Wu Biochemical Society Transactions 47 (6), 1609-1619, 2019 | 11 | 2019 |
| Achieving selectivity in space and time with DNA double-strand-break response and repair: molecular stages and scaffolds come with strings attached S Liang, SR Esswein, T Ochi, Q Wu, DB Ascher, D Chirgadze, BL Sibanda, ... Structural Chemistry 28, 161-171, 2017 | 11 | 2017 |
| Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining MJ Cabello-Lobato, M Jenner, M Cisneros-Aguirre, K Brüninghoff, ... Nucleic acids research 50 (8), 4732-4754, 2022 | 4 | 2022 |
| Guardians of the genome: DNA damage and repair Q Wu Essays in Biochemistry 64 (5), 683-685, 2020 | 2 | 2020 |
| Spatial and temporal organisation of multiprotein systems of cell regulation and signalling: What can we learn from NHEJ system of double-strand break repair? Q Wu, L Sibanda, T Ochi, VM Bolanos-Garcia, TL Blundell, DY Chirgadze Macromolecular Crystallography: Deciphering the Structure, Function and …, 2012 | 2 | 2012 |
| Microarray screening reveals a non-conventional SUMO-binding mode linked to DNA repair by non-homologous end-joining MJ Cabello-Lobato, M Jenner, CM Loch, SP Jackson, Q Wu, MJ Cliff, ... bioRxiv, 2021.01. 20.427433, 2021 | | 2021 |
| Structural studies of human DNA double-strand breaks repair non-homologous end joining protein complex XLF-XRCC4: dance in a helical way Q Wu University of Cambridge, 2012 | | 2012 |
Takashi OchiUniversity of LeedsVerified email at leeds.ac.uk
