Recent advances of the Povarov reaction in medicinal chemistry O Ghashghaei, C Masdeu, C Alonso, F Palacios, R Lavilla Drug Discovery Today: Technologies 29, 71-79, 2018 | 88 | 2018 |
Selectivity in multiple multicomponent reactions: types and synthetic applications O Ghashghaei, F Seghetti, R Lavilla Beilstein journal of organic chemistry 15 (1), 521-534, 2019 | 50 | 2019 |
Fluorogenic Trp (redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas VC LamáHo Chemical Science 11 (5), 1368-1374, 2020 | 46 | 2020 |
Multiple Multicomponent Reactions: Unexplored Substrates, Selective Processes and Versatile Chemotypes in Biomedicine O Ghashghaei, S Caputo, M Sintes, M Revés, N Kielland, C Estarellas, ... Chemistry–A European Journal, 2018 | 36 | 2018 |
Extended Multicomponent Reactions with Indole Aldehydes. Access to Unprecedented Polyheterocyclic Scaffolds, Ligands of the Aryl Hydrocarbon Receptor. O Ghashghaei, M Pedrola, F Seghetti, VV Martin, R Zavarce, M Babiak, ... Angewandte Chemie (International ed. in English), 2020 | 28 | 2020 |
Insertion of Isocyanides into N− Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds KG Kishore, O Ghashghaei, C Estarellas, MM Mestre, C Monturiol, ... Angewandte Chemie International Edition 55 (31), 8994-8998, 2016 | 26 | 2016 |
Multicomponent reactions upon the known drug trimethoprim as a source of novel antimicrobial agents M Pedrola, M Jorba, E Jardas, F Jardi, O Ghashghaei, M Viñas, R Lavilla Frontiers in Chemistry 7, 475, 2019 | 23 | 2019 |
A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy‐induced Cancer Cell Death N Barth, L Mendive-Tapia, R Subiros-Funosas, O Ghashghaie, R Lavilla, ... Angewandte Chemie International Edition, 2021 | 14 | 2021 |
Holistic approach to anti-knock agents: A high-throughput screening of aniline-like compounds A Viayna, O Ghashghaei, D Vilchez, C Estarellas, M Lopez, ... Fuel 305, 121518, 2021 | 12 | 2021 |
Modular Access to Tetrasubstituted Imidazolium Salts through Acid‐Catalyzed Addition of Isocyanides to Propargylamines O Ghashghaei, M Reves, N Kielland, R Lavilla European Journal of Organic Chemistry 2015 (20), 4383-4388, 2015 | 12 | 2015 |
Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations O Ghashghaei, CA Manna, E Vicente-García, M Revés, R Lavilla Beilstein Journal of Organic Chemistry 10 (1), 12-17, 2014 | 10 | 2014 |
Heterocycle-based multicomponent reactions in drug discovery: from hit finding to rational design P Nadal Rodríguez, O Ghashghaei, A Bagán, C Escolano, R Lavilla Biomedicines 10 (7), 1488, 2022 | 8 | 2022 |
Multicomponent reactions: A mighty journey partner for infectious tropical disease drug discovery D Muñoz-Torrero, R Lavilla, FJ Pérez-Areales, O Ghashghaei Annual Reports in Medicinal Chemistry 53, 181-217, 2019 | 6 | 2019 |
Tetrasubstituted imidazolium salts as potent antiparasitic agents against African and American trypanosomiases O Ghashghaei, N Kielland, M Revés, MC Taylor, JM Kelly, O Di Pietro, ... Molecules 23 (1), 177, 2018 | 6 | 2018 |
New trimethoprim-like molecules: bacteriological evaluation and insights into their action M Jorba, M Pedrola, O Ghashghaei, R Herráez, L Campos-Vicens, ... Antibiotics 10 (6), 709, 2021 | 5 | 2021 |
Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds P Nadal Rodríguez, O Ghashghaei, AM Schoepf, S Benson, M Vendrell, ... Angewandte Chemie 135 (41), e202303889, 2023 | 3 | 2023 |
The Prohibitin-Binding Compound Fluorizoline Activates the Integrated Stress Response through the eIF2α Kinase HRI I Sánchez-Vera, S Núñez-Vázquez, J Saura-Esteller, AM Cosialls, J Heib, ... International Journal of Molecular Sciences 24 (9), 8064, 2023 | 2 | 2023 |
Heterocycles as inputs in MCRs: An update O Ghashghaei, M Pedrola, C Escolano, R Lavilla Multicomponent Reactions towards Heterocycles: Concepts and Applications, 1-43, 2022 | 2 | 2022 |
Nonperturbative fluorogenic labeling of immunophilins enables the wash-free detection of immunosuppressants M Bertolini, L Mendive-Tapia, O Ghashghaei, A Reese, C Lochenie, ... ACS Central Science, 2024 | 1 | 2024 |
Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multicomponent Reactions A Trejo, C Masdeu, I Serrano-Pérez, M Pedrola, N Juanola, ... Antibiotics 12 (1), 83, 2023 | 1 | 2023 |