Structure-guided triple-code saturation mutagenesis: efficient tuning of the stereoselectivity of an epoxide hydrolase Z Sun, R Lonsdale, L Wu, G Li, A Li, J Wang, J Zhou, MT Reetz ACS Catalysis 6 (3), 1590-1597, 2016 | 116 | 2016 |
Biocatalysts for the pharmaceutical industry created by structure-guided directed evolution of stereoselective enzymes G Li, J Wang, MT Reetz Bioorganic & medicinal chemistry 26 (7), 1241-1251, 2018 | 103 | 2018 |
Enzymatic site-selectivity enabled by structure-guided directed evolution J Wang, G Li, MT Reetz Chemical communications 53 (28), 3916-3928, 2017 | 99 | 2017 |
Exploring substrate scope and stereoselectivity of P450 peroxygenase OleT JE in olefin-forming oxidative decarboxylation J Wang, R Lonsdale, MT Reetz Chemical communications 52 (52), 8131-8133, 2016 | 56 | 2016 |
Production of doramectin by rational engineering of the avermectin biosynthetic pathway JB Wang, HX Pan, GL Tang Bioorganic & medicinal chemistry letters 21 (11), 3320-3323, 2011 | 43 | 2011 |
P450-BM3-catalyzed sulfoxidation versus hydroxylation: a common or two different catalytically active species? J Wang, Q Huang, W Peng, P Wu, D Yu, B Chen, B Wang, MT Reetz Journal of the American Chemical Society 142 (4), 2068-2073, 2020 | 40 | 2020 |
Exploiting designed oxidase–peroxygenase mutual benefit system for asymmetric cascade reactions D Yu, J Wang, MT Reetz Journal of the American Chemical Society 141 (14), 5655-5658, 2019 | 39 | 2019 |
Chiral cascades J Wang, MT Reetz Nature Chemistry 7 (12), 948-949, 2015 | 37 | 2015 |
Chemo‐and stereoselective cytochrome P450‐BM3‐catalyzed sulfoxidation of 1‐thiochroman‐4‐ones enabled by directed evolution J Wang, A Ilie, MT Reetz Advanced Synthesis & Catalysis 359 (12), 2056-2060, 2017 | 29 | 2017 |
An O2-sensing stressosome from a Gram-negative bacterium X Jia, J Wang, S Rivera, D Duong, EE Weinert Nature communications 7 (1), 1-8, 2016 | 29 | 2016 |
Investigating substrate scope and enantioselectivity of a defluorinase by a stereochemical probe J Wang, A Ilie, S Yuan, MT Reetz Journal of the American Chemical Society 139 (32), 11241-11247, 2017 | 27 | 2017 |
Directed evolution of a plant glycosyltransferase for chemo-and regioselective glycosylation of pharmaceutically significant flavonoids Z Wen, ZM Zhang, L Zhong, J Fan, M Li, Y Ma, Y Zhou, W Zhang, B Guo, ... ACS Catalysis 11 (24), 14781-14790, 2021 | 26 | 2021 |
Characterization of AvaR1, an autoregulator receptor that negatively controls avermectins production in a high avermectin-producing strain JB Wang, F Zhang, JY Pu, J Zhao, QF Zhao, GL Tang Biotechnology letters 36, 813-819, 2014 | 25 | 2014 |
Harnessing fluoroacetate dehalogenase for defluorination of fluorocarboxylic acids: in silico and in vitro approach Y Li, Y Yue, H Zhang, Z Yang, H Wang, S Tian, J Wang, Q Zhang, ... Environment international 131, 104999, 2019 | 20 | 2019 |
Comprehensive understanding of fluoroacetate dehalogenase-catalyzed degradation of fluorocarboxylic acids: a QM/MM approach Y Yue, J Fan, G Xin, Q Huang, J Wang, Y Li, Q Zhang, W Wang Environmental Science & Technology 55 (14), 9817-9825, 2021 | 19 | 2021 |
Semirational design of fluoroacetate dehalogenase RPA1163 for kinetic resolution of α-fluorocarboxylic acids on a gram scale H Zhang, S Tian, Y Yue, M Li, W Tong, G Xu, B Chen, M Ma, Y Li, J Wang ACS Catalysis 10 (5), 3143-3151, 2020 | 18 | 2020 |
Enzyme-catalyzed C–F bond formation and cleavage W Tong, Q Huang, M Li, J Wang Bioresources and Bioprocessing 6, 1-8, 2019 | 18 | 2019 |
From semirational to rational design: Developing a substrate-coupled system of glucose dehydrogenase for asymmetric synthesis Q Yan, X Zhang, Y Chen, B Guo, P Zhou, B Chen, Q Huang, J Wang ACS Catalysis 12 (11), 6746-6755, 2022 | 15 | 2022 |
Structure-guided protein design of fluoroacetate dehalogenase for kinetic resolution of rac-2-bromobutyric acid S Wang, Z Cheng, Y Xu, L Yang, JB Wang, Z Tian, X Qu Green Synthesis and Catalysis 1 (1), 60-65, 2020 | 14 | 2020 |
Discovery of a P450-catalyzed oxidative defluorination mechanism toward chiral organofluorines: uncovering a hidden pathway Q Huang, X Zhang, Q Chen, S Tian, W Tong, W Zhang, Y Chen, M Ma, ... ACS catalysis 12 (1), 265-272, 2021 | 12 | 2021 |