ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets AJ Souers, JD Leverson, ER Boghaert, SL Ackler, ND Catron, J Chen, ... Nature medicine 19 (2), 202-208, 2013 | 3082 | 2013 |
Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL M Bruncko, TK Oost, BA Belli, H Ding, MK Joseph, A Kunzer, D Martineau, ... Journal of medicinal chemistry 50 (4), 641-662, 2007 | 411 | 2007 |
Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins CM Park, M Bruncko, J Adickes, J Bauch, H Ding, A Kunzer, KC Marsh, ... Journal of medicinal chemistry 51 (21), 6902-6915, 2008 | 406 | 2008 |
Rhodium (III)‐Catalyzed Intramolecular Annulation through C H Activation: Total Synthesis of (±)‐Antofine,(±)‐Septicine,(±)‐Tylophorine, and Rosettacin X Xu, Y Liu, CM Park Angewandte Chemie International Edition 37 (51), 9372-9376, 2012 | 301 | 2012 |
Apoptosis promoters M Bruncko, H Ding, SW Elmore, AR Kunzer, CL Lynch, WJ McClellan, ... US Patent 7,390,799, 2008 | 248* | 2008 |
Executive summary of stroke statistics in Korea 2018: a report from the Epidemiology Research Council of the Korean Stroke Society JY Kim, K Kang, J Kang, J Koo, DH Kim, BJ Kim, WJ Kim, EG Kim, JG Kim, ... Journal of stroke 21 (1), 42, 2019 | 229 | 2019 |
Expedient synthesis of highly substituted pyrroles via tandem rearrangement of α-diazo oxime ethers Y Jiang, WC Chan, CM Park Journal of the American Chemical Society 134 (9), 4104-4107, 2012 | 157 | 2012 |
Synthesis of the first members of a new class of biologically active bryostatin analogues PA Wender, J De Brabander, PG Harran, JM Jimenez, MFT Koehler, ... Journal of the American Chemical Society 120 (18), 4534-4535, 1998 | 156 | 1998 |
Synthesis of Pyridines by Carbenoid-Mediated Ring Opening of 2 H-Azirines. NSY Loy, A Singh, X Xu, CM Park Angewandte Chemie 125 (8), 2013 | 148 | 2013 |
The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1 PA Wender, J DeBrabander, PG Harran, JM Jimenez, MFT Koehler, ... Proceedings of the National Academy of Sciences 95 (12), 6624-6629, 1998 | 142 | 1998 |
Transition-Metal-Free Synthesis of Substituted Pyridines via Ring Expansion of 2-Allyl-2H-azirines Y Jiang, CM Park, TP Loh Organic letters 16 (13), 3432-3435, 2014 | 113 | 2014 |
Synthesis of unsymmetrical pyrazines based on α-diazo oxime ethers NSY Loy, S Kim, CM Park Organic letters 17 (3), 395-397, 2015 | 111 | 2015 |
Synthesis of 2-aminofurans and 2-unsubstituted furans via carbenoid-mediated [3+ 2] cycloaddition Y Jiang, VZY Khong, E Lourdusamy, CM Park Chemical communications 48 (25), 3133-3135, 2012 | 108 | 2012 |
Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases M Bruncko, H Ding, GA Doherty, SW Elmore, L Hasvold, L Hexamer, ... US Patent 8,586,754, 2013 | 106 | 2013 |
Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR AM Petros, JR Huth, T Oost, CM Park, H Ding, X Wang, H Zhang, ... Bioorganic & medicinal chemistry letters 20 (22), 6587-6591, 2010 | 103 | 2010 |
Stereoselective synthesis of α-diazo oxime ethers and their application in the synthesis of highly substituted pyrroles through a [3+ 2] cycloaddition E Lourdusamy, L Yao, CM Park Angew. Chem., Int. Ed 49, 7963-7967, 2010 | 103 | 2010 |
Apoptosis promoters M Bruncko, H Ding, S Elmore, A Kunzer, CL Lynch, W McClellan, CM Park, ... US Patent 7,767,684, 2010 | 97 | 2010 |
Chronic obstructive pulmonary disease (COPD): evaluation from clinical, immunological and bacterial pathogenesis perspectives DJ Hassett, MT Borchers, RJ Panos Journal of microbiology 52, 211-226, 2014 | 93 | 2014 |
Apoptosis promoters M Bruncko, H Ding, S Elmore, A Kunzer, CL Lynch, W McClellan, CM Park, ... US Patent 7,973,161, 2011 | 90 | 2011 |
Apoptosis promoters M Bruncko, H Ding, S Elmore, A Kunzer, CL Lynch, W McClellan, CM Park, ... US Patent 8,614,318, 2013 | 87 | 2013 |