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Rahul Singh Kathayat
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Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors
J Osipiuk, SA Azizi, S Dvorkin, M Endres, R Jedrzejczak, KA Jones, ...
Nature communications 12 (1), 743, 2021
3482021
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ...
Science 373 (6557), 931-936, 2021
226*2021
ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5
Y Cao, T Qiu, RS Kathayat, SA Azizi, AK Thorne, D Ahn, Y Fukata, ...
Nature chemical biology 15 (12), 1232-1240, 2019
852019
Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes
RS Kathayat, Y Cao, PD Elvira, PA Sandoz, ME Zaballa, MZ Springer, ...
Nature communications 9 (1), 334, 2018
832018
A fluorescent probe for cysteine depalmitoylation reveals dynamic APT signaling
RS Kathayat, PD Elvira, BC Dickinson
Nature chemical biology 13 (2), 150-152, 2017
742017
Sulfoxides as response elements for fluorescent chemosensors
RS Kathayat, NS Finney
Journal of the American Chemical Society 135 (34), 12612-12614, 2013
412013
Palmitoylation is required for TNF-R1 signaling
P Zingler, V Särchen, T Glatter, L Caning, C Saggau, RS Kathayat, ...
Cell Communication and Signaling 17, 1-16, 2019
382019
Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior
RS Sadeghi, K Kulej, RS Kathayat, BA Garcia, BC Dickinson, DC Brady, ...
Elife 7, e34362, 2018
342018
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays
Y Gupta, D Maciorowski, SE Zak, KA Jones, RS Kathayat, SA Azizi, ...
Methods 195, 57-71, 2021
332021
Michael addition-based probes for ratiometric fluorescence imaging of protein S-depalmitoylases in live cells and tissues
MW Beck, RS Kathayat, CM Cham, EB Chang, BC Dickinson
Chemical science 8 (11), 7588-7592, 2017
302017
Endothelial palmitoylation cycling coordinates vessel remodeling in peripheral artery disease
X Wei, S Adak, M Zayed, L Yin, C Feng, SL Speck, RS Kathayat, Q Zhang, ...
Circulation research 127 (2), 249-265, 2020
282020
Development of an Acrylamide-Based Inhibitor of Protein S-Acylation
SA Azizi, T Lan, C Delalande, RS Kathayat, F Banales Mejia, A Qin, ...
ACS chemical biology 16 (8), 1546-1556, 2021
242021
On the origins of nonradiative excited state relaxation in aryl sulfoxides relevant to fluorescent chemosensing
RS Kathayat, L Yang, T Sattasathuchana, L Zoppi, KK Baldridge, ...
Journal of the American Chemical Society 138 (49), 15889-15895, 2016
242016
A Fluorescent Probe with Improved Water Solubility Permits the Analysis of Protein S-Depalmitoylation Activity in Live Cells
T Qiu, RS Kathayat, Y Cao, MW Beck, BC Dickinson
Biochemistry 57 (2), 221-225, 2018
192018
Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach
Y Gupta, S Kumar, SE Zak, KA Jones, C Upadhyay, N Sharma, SA Azizi, ...
Bioorganic & Medicinal Chemistry 47, 116393, 2021
182021
Activity-Based Sensing of S-Depalmitoylases: Chemical Technologies and Biological Discovery
SA Azizi, RS Kathayat, BC Dickinson
Accounts of Chemical Research, 2019
182019
Palmitoylation couples insulin hypersecretion with β cell failure in diabetes
G Dong, S Adak, G Spyropoulos, Q Zhang, C Feng, L Yin, SL Speck, ...
Cell metabolism 35 (2), 332-344. e7, 2023
152023
Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration
AV Luebben, D Bender, S Becker, LM Crowther, I Erven, K Hofmann, ...
Science Advances 8 (15), eabj8633, 2022
152022
Measuring S-Depalmitoylation Activity In Vitro and In Live Cells with Fluorescent Probes
RS Kathayat, BC Dickinson
Protein Lipidation: Methods and Protocols, 99-109, 2019
52019
Poonam
Y Gupta, S Kumar, SE Zak, KA Jones, C Upadhyay, N Sharma, SA Azizi, ...
Herbert, AS, 2021
42021
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