Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors J Osipiuk, SA Azizi, S Dvorkin, M Endres, R Jedrzejczak, KA Jones, ... Nature communications 12 (1), 743, 2021 | 348 | 2021 |
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ... Science 373 (6557), 931-936, 2021 | 226* | 2021 |
ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5 Y Cao, T Qiu, RS Kathayat, SA Azizi, AK Thorne, D Ahn, Y Fukata, ... Nature chemical biology 15 (12), 1232-1240, 2019 | 85 | 2019 |
Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes RS Kathayat, Y Cao, PD Elvira, PA Sandoz, ME Zaballa, MZ Springer, ... Nature communications 9 (1), 334, 2018 | 83 | 2018 |
A fluorescent probe for cysteine depalmitoylation reveals dynamic APT signaling RS Kathayat, PD Elvira, BC Dickinson Nature chemical biology 13 (2), 150-152, 2017 | 74 | 2017 |
Sulfoxides as response elements for fluorescent chemosensors RS Kathayat, NS Finney Journal of the American Chemical Society 135 (34), 12612-12614, 2013 | 41 | 2013 |
Palmitoylation is required for TNF-R1 signaling P Zingler, V Särchen, T Glatter, L Caning, C Saggau, RS Kathayat, ... Cell Communication and Signaling 17, 1-16, 2019 | 38 | 2019 |
Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior RS Sadeghi, K Kulej, RS Kathayat, BA Garcia, BC Dickinson, DC Brady, ... Elife 7, e34362, 2018 | 34 | 2018 |
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays Y Gupta, D Maciorowski, SE Zak, KA Jones, RS Kathayat, SA Azizi, ... Methods 195, 57-71, 2021 | 33 | 2021 |
Michael addition-based probes for ratiometric fluorescence imaging of protein S-depalmitoylases in live cells and tissues MW Beck, RS Kathayat, CM Cham, EB Chang, BC Dickinson Chemical science 8 (11), 7588-7592, 2017 | 30 | 2017 |
Endothelial palmitoylation cycling coordinates vessel remodeling in peripheral artery disease X Wei, S Adak, M Zayed, L Yin, C Feng, SL Speck, RS Kathayat, Q Zhang, ... Circulation research 127 (2), 249-265, 2020 | 28 | 2020 |
Development of an Acrylamide-Based Inhibitor of Protein S-Acylation SA Azizi, T Lan, C Delalande, RS Kathayat, F Banales Mejia, A Qin, ... ACS chemical biology 16 (8), 1546-1556, 2021 | 24 | 2021 |
On the origins of nonradiative excited state relaxation in aryl sulfoxides relevant to fluorescent chemosensing RS Kathayat, L Yang, T Sattasathuchana, L Zoppi, KK Baldridge, ... Journal of the American Chemical Society 138 (49), 15889-15895, 2016 | 24 | 2016 |
A Fluorescent Probe with Improved Water Solubility Permits the Analysis of Protein S-Depalmitoylation Activity in Live Cells T Qiu, RS Kathayat, Y Cao, MW Beck, BC Dickinson Biochemistry 57 (2), 221-225, 2018 | 19 | 2018 |
Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach Y Gupta, S Kumar, SE Zak, KA Jones, C Upadhyay, N Sharma, SA Azizi, ... Bioorganic & Medicinal Chemistry 47, 116393, 2021 | 18 | 2021 |
Activity-Based Sensing of S-Depalmitoylases: Chemical Technologies and Biological Discovery SA Azizi, RS Kathayat, BC Dickinson Accounts of Chemical Research, 2019 | 18 | 2019 |
Palmitoylation couples insulin hypersecretion with β cell failure in diabetes G Dong, S Adak, G Spyropoulos, Q Zhang, C Feng, L Yin, SL Speck, ... Cell metabolism 35 (2), 332-344. e7, 2023 | 15 | 2023 |
Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration AV Luebben, D Bender, S Becker, LM Crowther, I Erven, K Hofmann, ... Science Advances 8 (15), eabj8633, 2022 | 15 | 2022 |
Measuring S-Depalmitoylation Activity In Vitro and In Live Cells with Fluorescent Probes RS Kathayat, BC Dickinson Protein Lipidation: Methods and Protocols, 99-109, 2019 | 5 | 2019 |
Poonam Y Gupta, S Kumar, SE Zak, KA Jones, C Upadhyay, N Sharma, SA Azizi, ... Herbert, AS, 2021 | 4 | 2021 |