| Tacrine–melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties MI Fernández‐Bachiller, C Pérez, NE Campillo, JA Páez, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (5), 828-841, 2009 | 152 | 2009 |
| Plant-based heterologous expression of Mal d 2, a thaumatin-like protein and allergen of apple (Malus domestica), and its characterization as an antifungal protein M Krebitz, B Wagner, F Ferreira, C Peterbauer, N Campillo, M Witty, ... Journal of molecular biology 329 (4), 721-730, 2003 | 152 | 2003 |
| Homology models of the cannabinoid CB1 and CB2 receptors. A docking analysis study C Montero, NE Campillo, P Goya, JA Páez European journal of medicinal chemistry 40 (1), 75-83, 2005 | 109 | 2005 |
| Directed mutagenesis alters the stereochemistry of catalysis by isolated ketoreductase domains from the erythromycin polyketide synthase A Baerga-Ortiz, B Popovic, AP Siskos, HM O'Hare, D Spiteller, ... Chemistry & biology 13 (3), 277-285, 2006 | 102 | 2006 |
| Exploring the binding sites of glycogen synthase kinase 3. Identification and characterization of allosteric modulation cavities V Palomo, I Soteras, DI Perez, C Perez, C Gil, NE Campillo, A Martinez Journal of medicinal chemistry 54 (24), 8461-8470, 2011 | 73 | 2011 |
| 5-imino-1, 2, 4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3 V Palomo, DI Perez, C Perez, JA Morales-Garcia, I Soteras, S Alonso-Gil, ... Journal of medicinal chemistry 55 (4), 1645-1661, 2012 | 62 | 2012 |
| Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model M Redondo, JG Zarruk, P Ceballos, DI Pérez, C Pérez, A Perez-Castillo, ... European journal of medicinal chemistry 47, 175-185, 2012 | 60 | 2012 |
| Chagas disease: progress and new perspectives F Sanchez-Sancho, NE Campillo, JA Páez Current Medicinal Chemistry 17 (5), 423-452, 2010 | 59 | 2010 |
| Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1 I Pérez-Dorado, NE Campillo, B Monterroso, D Hesek, M Lee, JA Páez, ... Journal of Biological Chemistry 282 (34), 24990-24999, 2007 | 59 | 2007 |
| Crystal structure of CbpF, a bifunctional choline‐binding protein and autolysis regulator from Streptococcus pneumoniae R Molina, A González, M Stelter, I Pérez‐Dorado, R Kahn, M Morales, ... EMBO reports 10 (3), 246-251, 2009 | 58 | 2009 |
| The origin of the serum resistance associated (SRA) gene and a model of the structure of the SRA polypeptide from Trypanosoma brucei rhodesiense. N Campillo, M Carrington Molecular and biochemical parasitology 127 (1), 79-84, 2003 | 57 | 2003 |
| Synthesis, structural analysis, and biological evaluation of thioxoquinazoline derivatives as phosphodiesterase 7 inhibitors T Castaño, H Wang, NE Campillo, S Ballester, C González‐García, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (5), 866-876, 2009 | 53 | 2009 |
| Electrospray mass spectrometry evidence for an oxo-manganese (V) species generated during the reaction of manganese triazacyclononane complexes with H 2 O 2 and 4-methoxyphenol … BC Gilbert, NWJ Kamp, JRL Smith Journal of the Chemical Society, Perkin Transactions 2, 1841-1844, 1998 | 53 | 1998 |
| An iterative structure‐assisted approach to sequence alignment and comparative modeling DF Burke, CM Deane, HA Nagarajaram, N Campillo, M Martin‐Martinez, ... Proteins: Structure, Function, and Bioinformatics 37 (S3), 55-60, 1999 | 48 | 1999 |
| p‐Coumaric acid decarboxylase from Lactobacillus plantarum: Structural insights into the active site and decarboxylation catalytic mechanism H Rodríguez, I Angulo, B de las Rivas, N Campillo, JA Páez, R Muñoz, ... Proteins: Structure, Function, and Bioinformatics 78 (7), 1662-1676, 2010 | 47 | 2010 |
| PDE7 inhibitors as new drugs for neurological and inflammatory disorders C Gil, NE Campillo, DI Perez, A Martinez Expert Opinion on Therapeutic Patents 18 (10), 1127-1139, 2008 | 40 | 2008 |
| Artificial neural networks in ADMET modeling: prediction of blood–brain barrier permeation A Guerra, JA Páez, NE Campillo QSAR & Combinatorial Science 27 (5), 586-594, 2008 | 40 | 2008 |
| Sequence‐structure homology recognition by iterative alignment refinement and comparative modeling MG Williams, H Shirai, J Shi, HG Nagendra, J Mueller, K Mizuguchi, ... Proteins: Structure, Function, and Bioinformatics 45 (S5), 92-97, 2001 | 40 | 2001 |
| Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds M Redondo, J Brea, DI Perez, I Soteras, C Val, C Perez, ... Journal of medicinal chemistry 55 (7), 3274-3284, 2012 | 38 | 2012 |
| Development of second generation amidinohydrazones, thio-and semicarbazones as Trypanosoma cruzi-inhibitors bearing benzofuroxan and benzimidazole 1, 3-dioxide core scaffolds A Merlino, D Benitez, S Chavez, J Da Cunha, P Hernández, LW Tinoco, ... Medchemcomm 1 (3), 216-228, 2010 | 38 | 2010 |
