Serine and threonine residues bend α-helices in the χ1= g− conformation JA Ballesteros, X Deupi, M Olivella, EEJ Haaksma, L Pardo Biophysical Journal 79 (5), 2754-2760, 2000 | 208 | 2000 |
Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3 C Govaerts, A Bondue, JY Springael, M Olivella, X Deupi, E Le Poul, ... Journal of Biological Chemistry 278 (3), 1892-1903, 2003 | 117 | 2003 |
Ser and Thr residues modulate the conformation of pro-kinked transmembrane α-helices X Deupi, M Olivella, C Govaerts, JA Ballesteros, M Campillo, L Pardo Biophysical Journal 86 (1), 105-115, 2004 | 112 | 2004 |
GPCRmd uncovers the dynamics of the 3D-GPCRome I Rodríguez-Espigares, M Torrens-Fontanals, JKS Tiemann, ... Nature Methods 17 (8), 777-787, 2020 | 111 | 2020 |
Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives ML López-Rodríguez, E Porras, MJ Morcillo, B Benhamú, LJ Soto, ... Journal of medicinal chemistry 46 (26), 5638-5650, 2003 | 100 | 2003 |
Relation between sequence and structure in membrane proteins M Olivella, A Gonzalez, L Pardo, X Deupi Bioinformatics 29 (13), 1589-1592, 2013 | 83 | 2013 |
l-Serine dietary supplementation is associated with clinical improvement of loss-of-function GRIN2B-related pediatric encephalopathy D Soto, M Olivella, C Grau, J Armstrong, C Alcon, X Gasull, ... Science signaling 12 (586), eaaw0936, 2019 | 65 | 2019 |
Design, synthesis and pharmacological evaluation of 5-hydroxytryptamine1a receptor ligands to explore the three-dimensional structure of the receptor ML López-Rodrı́guez, B Vicente, X Deupi, S Barrondo, M Olivella, ... Molecular pharmacology 62 (1), 15-21, 2002 | 62 | 2002 |
Analysis of the interactions of sulfur‐containing amino acids in membrane proteins JC Gómez‐Tamayo, A Cordomí, M Olivella, E Mayol, D Fourmy, L Pardo Protein Science 25 (8), 1517-1524, 2016 | 57 | 2016 |
The role of Cysteine 6.47 in class A GPCRs M Olivella, G Caltabiano, A Cordomi BMC structural biology 13, 1-11, 2013 | 47 | 2013 |
SirT7 auto-ADP-ribosylation regulates glucose starvation response through mH2A1 NG Simonet, JK Thackray, BN Vazquez, A Ianni, M Espinosa-Alcantud, ... Science advances 6 (30), eaaz2590, 2020 | 43 | 2020 |
Influence of the environment in the conformation of α-helices studied by protein database search and molecular dynamics simulations M Olivella, X Deupi, C Govaerts, L Pardo Biophysical journal 82 (6), 3207-3213, 2002 | 39 | 2002 |
GRIN database: A unified and manually curated repertoire of GRIN variants A García‐Recio, A Santos‐Gómez, D Soto, N Julia‐Palacios, ... Human mutation 42 (1), 8-18, 2021 | 36 | 2021 |
Influence of the g− conformation of Ser and Thr on the structure of transmembrane helices X Deupi, M Olivella, A Sanz, N Dölker, M Campillo, L Pardo Journal of structural biology 169 (1), 116-123, 2010 | 31 | 2010 |
Computational Model of the Complex between GR113808 and the 5-HT4 Receptor Guided by Site-Directed Mutagenesis and the Crystal Structure of Rhodopsin ML López-Rodríguez, M Murcia, B Benhamú, M Olivella, M Campillo, ... Journal of computer-aided molecular design 15, 1025-1033, 2001 | 26 | 2001 |
Design and synthesis of S-(−)-2-[[4-(napht-1-yl) piperazin-1-yl] methyl]-1, 4-dioxoperhydropyrrolo [1, 2-a] pyrazine (CSP-2503) using computational simulation. A 5-HT1A … ML López-Rodrı́guez, MJ Morcillo, E Fernández, B Benhamú, I Tejada, ... Bioorganic & medicinal chemistry letters 13 (8), 1429-1432, 2003 | 25 | 2003 |
HomolWat: a web server tool to incorporate ‘homologous’ water molecules into GPCR structures E Mayol, A García-Recio, JKS Tiemann, PW Hildebrand, ... Nucleic acids research 48 (W1), W54-W59, 2020 | 20 | 2020 |
Disease-associated GRIN protein truncating variants trigger NMDA receptor loss-of-function A Santos-Gómez, F Miguez-Cabello, A García-Recio, S Locubiche-Serra, ... Human molecular genetics 29 (24), 3859-3871, 2020 | 19 | 2020 |
Mechanisms of CPT1C-dependent AMPAR trafficking enhancement E Gratacòs-Batlle, M Olivella, N Sánchez-Fernández, N Yefimenko, ... Frontiers in Molecular Neuroscience 11, 275, 2018 | 18 | 2018 |
TMSNP: a web server to predict pathogenesis of missense mutations in the transmembrane region of membrane proteins A Garcia-Recio, JC Gómez-Tamayo, I Reina, M Campillo, A Cordomí, ... NAR Genomics and Bioinformatics 3 (1), lqab008, 2021 | 10 | 2021 |