Influence of local anesthetics upon human polymorphonuclear leukocyte function in vitro. Reduction of lysosomal enzyme release and superoxide anion production. IM Goldstein, S Lind, S Hoffstein, G Weissmann The Journal of experimental medicine 146 (2), 483-494, 1977 | 151 | 1977 |
Neutrophil signaling that challenges dogmata of G protein-coupled receptor regulated functions C Dahlgren, A Holdfeldt, S Lind, J Mårtensson, M Gabl, L Björkman, ... ACS Pharmacology & Translational Science 3 (2), 203-220, 2020 | 33 | 2020 |
Functional selective ATP receptor signaling controlled by the free fatty acid receptor 2 through a novel allosteric modulation mechanism S Lind, A Holdfeldt, J Mårtensson, M Sundqvist, L Björkman, H Forsman, ... The FASEB Journal 33 (6), 6887-6903, 2019 | 26 | 2019 |
Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949 S Lind, M Sundqvist, R Holmdahl, C Dahlgren, H Forsman, P Olofsson Biochemical Pharmacology 166, 163-173, 2019 | 25 | 2019 |
Mitocryptides from human mitochondrial DNA–encoded proteins activate neutrophil formyl peptide receptors: receptor preference and signaling properties M Gabl, M Sundqvist, A Holdfeldt, S Lind, J Mårtensson, K Christenson, ... The Journal of Immunology 200 (9), 3269-3282, 2018 | 22 | 2018 |
Interdependent allosteric free fatty acid receptor 2 modulators synergistically induce functional selective activation and desensitization in neutrophils S Lind, A Holdfeldt, J Mårtensson, M Sundqvist, TP Kenakin, L Björkman, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (6), 118689, 2020 | 20 | 2020 |
Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex S Lind, C Dahlgren, R Holmdahl, P Olofsson, H Forsman Journal of Leucocyte Biology 109 (6), 1105-1120, 2021 | 19 | 2021 |
G protein coupled pattern recognition receptors expressed in neutrophils: recognition, activation/modulation, signaling and receptor regulated functions C Dahlgren, S Lind, J Mårtensson, L Björkman, Y Wu, M Sundqvist, ... Immunological Reviews 314 (1), 69-92, 2023 | 14 | 2023 |
Identification of Residues Critical for FPR2 Activation by the Cryptic Peptide Mitocryptide-2 Originating from the Mitochondrial DNA–Encoded Cytochrome b S Lind, M Gabl, A Holdfeldt, J Mårtensson, M Sundqvist, K Nishino, ... The Journal of Immunology 202 (9), 2710-2719, 2019 | 13 | 2019 |
Multiple ligand recognition sites in free fatty acid receptor 2 (FFA2R) direct distinct neutrophil activation patterns S Lind, A Holdfeldt, J Mårtensson, KL Granberg, H Forsman, C Dahlgren Biochemical Pharmacology 193, 114762, 2021 | 8 | 2021 |
The PAR4-derived pepducin P4Pal10 lacks effect on neutrophil GPCRs that couple to gαq for signaling but distinctly modulates function of the gαi-coupled FPR2 and FFAR2 A Holdfeldt, S Lind, C Hesse, C Dahlgren, H Forsman Biochemical Pharmacology 180, 114143, 2020 | 8 | 2020 |
Allosteric receptor modulation uncovers an FFA2R antagonist as a positive orthosteric modulator/agonist in disguise S Lind, DO Hoffmann, H Forsman, C Dahlgren Cellular signalling 90, 110208, 2022 | 7 | 2022 |
The ketone body acetoacetate activates human neutrophils through FFAR2 J Mårtensson, L Björkman, S Lind, MB Viklund, L Zhang, S Gutierrez, ... Journal of Leukocyte Biology 113 (6), 577-587, 2023 | 5 | 2023 |
Weissmann 6. Influence of local anesthetics upon human polymorphonuclear leukocyte function in vib. 0. Reduction of lysosomal enzyme release and superoxide anion production IM Goldstein, S Lind, S Hoffstein Journal of Experimental Medicine 146, 483-494, 1977 | 5 | 1977 |
Phenol-soluble modulin α and β display divergent roles in mice with staphylococcal septic arthritis Z Hu, PK Kopparapu, P Ebner, M Mohammad, S Lind, A Jarneborn, ... Communications Biology 5 (1), 910, 2022 | 3 | 2022 |
The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs S Lind, KL Granberg, H Forsman, C Dahlgren Plos one 18 (4), e0268363, 2023 | 2 | 2023 |
The Allosterically Modulated Free Fatty Acid Receptor 2 is Transactivated by an Increase in the Cytosolic Concentration of Calcium Ions S Lind, Y Wu, M Sundqvist, H Forsman, C Dahlgren bioRxiv, 2022.10. 15.512353, 2022 | 2 | 2022 |
Structural Determinants in the Staphylococcus aureus–Derived Phenol-Soluble Modulin α2 Peptide Required for Neutrophil Formyl Peptide Receptor Activation M Viklund, J Fredriksson, A Holdfeldt, S Lind, H Franzyk, C Dahlgren, ... The Journal of Immunology 208 (7), 1632-1641, 2022 | 2 | 2022 |
An increase in the cytosolic concentration of free calcium ions activates the neutrophil NADPH-oxidase provided that the free fatty acid receptor 2 has been allosterically … S Lind, Y Wu, M Sundqvist, H Forsman, C Dahlgren Cellular Signalling 107, 110687, 2023 | 1 | 2023 |
Signals Generated by Neutrophil Receptors for Danger Molecules Transactivate Allosterically Modulated FFA2R: Distinct response patterns are mediated by modulators recognized by … S Lind, KL Granberg, H Forsman, C Dahlgren BioRxiv, 2022.04. 29.489985, 2022 | 1 | 2022 |