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Shanshan Deng
Shanshan Deng
University of Tennessee Health Science Center
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Cited by
Year
The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy
N Albadari, S Deng, W Li
Expert opinion on drug discovery 14 (7), 667-682, 2019
2522019
Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy
KE Arnst, S Banerjee, H Chen, S Deng, DJ Hwang, W Li, DD Miller
Medicinal research reviews 39 (4), 1398-1426, 2019
1152019
Heterocyclic-fused pyrimidines as novel tubulin polymerization inhibitors targeting the colchicine binding site: structural basis and antitumor efficacy
S Banerjee, KE Arnst, Y Wang, G Kumar, S Deng, L Yang, G Li, J Yang, ...
Journal of medicinal chemistry 61 (4), 1704-1718, 2018
962018
Structure–activity relationship study of novel 6-aryl-2-benzoyl-pyridines as tubulin polymerization inhibitors with potent antiproliferative properties
H Chen, S Deng, Y Wang, N Albadari, G Kumar, D Ma, W Li, SW White, ...
Journal of Medicinal Chemistry 63 (2), 827-846, 2019
392019
Design, synthesis, and biological evaluation of stable colchicine-binding site tubulin inhibitors 6-aryl-2-benzoyl-pyridines as potential anticancer agents
H Chen, S Deng, N Albadari, MK Yun, S Zhang, Y Li, D Ma, DN Parke, ...
Journal of medicinal chemistry 64 (16), 12049-12074, 2021
342021
An orally available tubulin inhibitor, VERU-111, suppresses triple-negative breast cancer tumor growth and metastasis and bypasses taxane resistance
S Deng, RI Krutilina, Q Wang, Z Lin, DN Parke, HC Playa, H Chen, ...
Molecular cancer therapeutics 19 (2), 348-363, 2020
282020
Orally available tubulin inhibitor VERU-111 enhances antitumor efficacy in paclitaxel-resistant lung cancer
F Mahmud, S Deng, H Chen, DD Miller, W Li
Cancer letters 495, 76-88, 2020
222020
Repression of intestinal transporters and FXR-FGF15 signaling explains bile acids dysregulation in experimental colitis-associated colon cancer
L Cao, Y Che, T Meng, S Deng, J Zhang, M Zhao, W Xu, D Wang, Z Pu, ...
Oncotarget 8 (38), 63665, 2017
202017
Cabozantinib for HCC treatment, from clinical back to experimental models
S Deng, A Solinas, DF Calvisi
Frontiers in oncology 11, 756672, 2021
162021
An on-line high-performance liquid chromatography− diode-array detector− multi-stage mass spectrometry− deoxyribonucleic acid− 4′, 6-diamidino-2-phenylindole− fluorescence …
S Li, H Jiang, Z Lin, S Deng, Y Guan, H Wang, S Chen
Journal of Chromatography A 1424, 37-50, 2015
162015
X-ray crystallography-guided design, antitumor efficacy, and QSAR analysis of metabolically stable cyclopenta-pyrimidinyl dihydroquinoxalinone as a potent tubulin …
S Banerjee, F Mahmud, S Deng, L Ma, MK Yun, SO Fakayode, KE Arnst, ...
Journal of medicinal chemistry 64 (17), 13072-13095, 2021
142021
Recent advances in antibody-drug conjugates for breast cancer treatment
S Deng, Z Lin, W Li
Current Medicinal Chemistry 24 (23), 2505-2527, 2017
132017
SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis
S Deng, S Banerjee, H Chen, S Pochampally, Y Wang, MK Yun, ...
Cancer letters 555, 216046, 2023
82023
Nanoformulation design and therapeutic potential of a novel tubulin inhibitor in pancreatic cancer
RS Bhattarai, V Kumar, S Romanova, J Bariwal, H Chen, S Deng, ...
Journal of controlled release 329, 585-597, 2021
72021
Discovery of a highly selective and potent TRPC3 inhibitor with high metabolic stability and low toxicity
S Zhang, LO Romero, S Deng, J Wang, Y Li, L Yang, DJ Hamilton, ...
ACS Medicinal Chemistry Letters 12 (4), 572-578, 2021
62021
pH-sensitive nanomedicine of novel tubulin polymerization inhibitor for lung metastatic melanoma
RS Bhattarai, J Bariwal, V Kumar, C Hao, S Deng, W Li, RI Mahato
Journal of Controlled Release 350, 569-583, 2022
52022
Colchicine-binding site agent CH-2-77 as a potent tubulin inhibitor suppressing triple-negative breast cancer
S Deng, RI Krutilina, KL Hartman, H Chen, DN Parke, R Wang, F Mahmud, ...
Molecular cancer therapeutics 21 (7), 1103-1114, 2022
52022
Synthesis and biological evaluation of selective survivin inhibitors derived from the MX-106 hydroxyquinoline scaffold
N Albadari, S Deng, H Chen, G Zhao, J Yue, S Zhang, DD Miller, Z Wu, ...
European journal of medicinal chemistry 224, 113719, 2021
52021
Molecular modelling guided design, synthesis and QSAR analysis of new small molecule non-lipid autotaxin inhibitors
S Banerjee, DD Norman, S Deng, SO Fakayode, SC Lee, AL Parrill, W Li, ...
Bioorganic chemistry 103, 104188, 2020
52020
Combination of AFP vaccine and immune checkpoint inhibitors slows hepatocellular carcinoma progression in preclinical models
X Lu, S Deng, J Xu, BL Green, H Zhang, G Cui, Y Zhou, Y Zhang, H Xu, ...
The Journal of Clinical Investigation 133 (11), 2023
22023
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