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chengguo xing
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Year
Chalcone: a privileged structure in medicinal chemistry
C Zhuang, W Zhang, C Sheng, W Zhang, C Xing, Z Miao
Chemical reviews 117 (12), 7762-7810, 2017
11932017
Diverse molecular targets for chalcones with varied bioactivities
B Zhou, C Xing
Medicinal chemistry 5 (8), 388, 2015
2322015
Structure− activity relationship studies of chalcone leading to 3-hydroxy-4, 3′, 4′, 5′-tetramethoxychalcone and its analogues as potent nuclear factor κB inhibitors and …
B Srinivasan, TE Johnson, R Lad, C Xing
Journal of medicinal chemistry 52 (22), 7228-7235, 2009
2202009
A detection system based on giant magnetoresistive sensors and high‐moment magnetic nanoparticles demonstrates zeptomole sensitivity: potential for personalized medicine
B Srinivasan, Y Li, Y Jing, YH Xu, X Yao, C Xing, JP Wang
Angewandte Chemie International Edition 48 (15), 2764-2767, 2009
1712009
Rapid identification of Keap1–Nrf2 small-molecule inhibitors through structure-based virtual screening and hit-based substructure search
C Zhuang, S Narayanapillai, W Zhang, YY Sham, C Xing
Journal of medicinal chemistry 57 (3), 1121-1126, 2014
1412014
A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy
W He, Q Wang, B Srinivasan, J Xu, MT Padilla, Z Li, X Wang, Y Liu, X Gou, ...
Oncogene 33 (23), 3004-3013, 2014
1232014
Nanomagnetic competition assay for low-abundance protein biomarker quantification in unprocessed human sera
Y Li, B Srinivasan, Y Jing, X Yao, MA Hugger, JP Wang, C Xing
Journal of the American Chemical Society 132 (12), 4388-4392, 2010
1072010
Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds
J Zhang, L Li, C Jiang, C Xing, SH Kim, J Lu
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2012
932012
Inhibitor of apoptosis protein (IAP) antagonists in anticancer agent discovery: Current status and perspectives
H Cong, L Xu, Y Wu, Z Qu, T Bian, W Zhang, C Xing, C Zhuang
Journal of Medicinal Chemistry 62 (12), 5750-5772, 2019
922019
sHA 14-1, a stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypasses drug resistances and synergizes cancer therapies in human leukemia cell
D Tian, SG Das, JM Doshi, J Peng, J Lin, C Xing
Cancer letters 259 (2), 198-208, 2008
842008
After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial …
J Ding, BHM Mooers, Z Zhang, J Kale, D Falcone, J McNichol, B Huang, ...
Journal of Biological Chemistry 289 (17), 11873-11896, 2014
832014
Structure−Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4H-chromene-3-carboxylate (sHA 14-1) and Its …
SG Das, JM Doshi, D Tian, SN Addo, B Srinivasan, DL Hermanson, ...
Journal of medicinal chemistry 52 (19), 5937-5949, 2009
832009
Structure–Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate …
SG Das, B Srinivasan, DL Hermanson, NP Bleeker, JM Doshi, R Tang, ...
Journal of medicinal chemistry 54 (16), 5937-5948, 2011
682011
A three-layer competition-based giant magnetoresistive assay for direct quantification of endoglin from human urine
B Srinivasan, Y Li, Y Jing, C Xing, J Slaton, JP Wang
Analytical chemistry 83 (8), 2996-3002, 2011
632011
Preparation of penta-O-galloyl-β-d-glucose from tannic acid and plasma pharmacokinetic analyses by liquid–liquid extraction and reverse-phase HPLC
L Li, AA Shaik, J Zhang, K Nhkata, L Wang, Y Zhang, C Xing, SH Kim, ...
Journal of pharmaceutical and biomedical analysis 54 (3), 545-550, 2011
632011
Small molecules inhibiting Keap1–Nrf2 protein–protein interactions: a novel approach to activate Nrf2 function
C Zhuang, Z Wu, C Xing, Z Miao
MedChemComm 8 (2), 286-294, 2017
612017
Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria
D Hermanson, SN Addo, AA Bajer, JS Marchant, SGK Das, B Srinivasan, ...
Molecular pharmacology 76 (3), 667-678, 2009
612009
Kava for the treatment of generalised anxiety disorder (K-GAD): study protocol for a randomised controlled trial
KM Savage, CK Stough, GJ Byrne, A Scholey, C Bousman, J Murphy, ...
Trials 16, 1-13, 2015
602015
Ethyl-2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H- chromene-3-carboxylate (HA 14-1), a Prototype Small-Molecule Antagonist against Antiapoptotic Bcl …
JM Doshi, D Tian, C Xing
Molecular pharmaceutics 4 (6), 919-928, 2007
582007
Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1
C Xing, L Wang, XH Tang, YY Sham
Bioorganic & medicinal chemistry 15 (5), 2167-2176, 2007
582007
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