Replication by human DNA polymerase-ι occurs by Hoogsteen base-pairing DT Nair, RE Johnson, S Prakash, L Prakash, AK Aggarwal Nature 430 (6997), 377-380, 2004 | 373 | 2004 |
Rev1 employs a novel mechanism of DNA synthesis using a protein template DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal Science 309 (5744), 2219-2222, 2005 | 284 | 2005 |
Human DNA polymerase κ encircles DNA: implications for mismatch extension and lesion bypass S Lone, SA Townson, SN Uljon, RE Johnson, A Brahma, DT Nair, ... Molecular cell 25 (4), 601-614, 2007 | 270 | 2007 |
Human DNA polymerase ι incorporates dCTP opposite template G via a G. C+ Hoogsteen base pair DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal Structure 13 (10), 1569-1577, 2005 | 155 | 2005 |
Fast native-SAD phasing for routine macromolecular structure determination T Weinert, V Olieric, S Waltersperger, E Panepucci, L Chen, H Zhang, ... Nature Methods 12 (2), 131-133, 2015 | 144 | 2015 |
Hoogsteen base pair formation promotes synthesis opposite the 1, N 6-ethenodeoxyadenosine lesion by human DNA polymerase ι DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal Nature structural & molecular biology 13 (7), 619-625, 2006 | 142 | 2006 |
Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response DT Nair, K Singh, Z Siddiqui, BP Nayak, KVS Rao, DM Salunke The Journal of Immunology 168 (5), 2371-2382, 2002 | 115 | 2002 |
Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 virus N Narayanan, DT Nair IUBMB Life, 2020 | 84 | 2020 |
Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity YK Gupta, DT Nair, RP Wharton, AK Aggarwal Structure 16 (4), 549-557, 2008 | 83 | 2008 |
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-ι active site DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal Structure 14 (4), 749-755, 2006 | 73 | 2006 |
Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction J Kottur, DT Nair Nucleic Acids Research, 2018 | 65 | 2018 |
Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal Structure 16 (2), 239-245, 2008 | 65 | 2008 |
RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state P Surana, V Satchidanandam, DT Nair Nucleic acids research 42 (4), 2758-2773, 2014 | 62 | 2014 |
DNA synthesis across an abasic lesion by human DNA polymerase ι DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal Structure 17 (4), 530-537, 2009 | 46 | 2009 |
A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli A Sharma, J Kottur, N Narayanan, DT Nair Nucleic acids research 41 (9), 5104-5114, 2013 | 45 | 2013 |
Crystal structure of an antibody bound to an immunodominant peptide epitope: novel features in peptide-antibody recognition DT Nair, K Singh, N Sahu, KVS Rao, DM Salunke The Journal of Immunology 165 (12), 6949-6955, 2000 | 45 | 2000 |
Reactive oxygen species play an important role in the bactericidal activity of quinolone antibiotics J Kottur, DT Nair Angewandte Chemie 128 (7), 2443-2446, 2016 | 43 | 2016 |
DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal Journal of molecular biology 406 (1), 18-28, 2011 | 43 | 2011 |
Mimicry of native peptide antigens by the corresponding retro-inverso analogs is dependent on their intrinsic structure and interaction propensities DT Nair, KJ Kaur, K Singh, P Mukherjee, D Rajagopal, A George, V Bal, ... The Journal of Immunology 170 (3), 1362-1373, 2003 | 41 | 2003 |
Structure of the induced antibacterial protein from tasar silkworm, Antheraea mylitta Implications to molecular evolution D Jain, DT Nair, GJ Swaminathan, EG Abraham, J Nagaraju, DM Salunke Journal of Biological Chemistry 276 (44), 41377-41382, 2001 | 41 | 2001 |