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Deepak Thankappan Nair
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Replication by human DNA polymerase-ι occurs by Hoogsteen base-pairing
DT Nair, RE Johnson, S Prakash, L Prakash, AK Aggarwal
Nature 430 (6997), 377-380, 2004
3732004
Rev1 employs a novel mechanism of DNA synthesis using a protein template
DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal
Science 309 (5744), 2219-2222, 2005
2842005
Human DNA polymerase κ encircles DNA: implications for mismatch extension and lesion bypass
S Lone, SA Townson, SN Uljon, RE Johnson, A Brahma, DT Nair, ...
Molecular cell 25 (4), 601-614, 2007
2702007
Human DNA polymerase ι incorporates dCTP opposite template G via a G. C+ Hoogsteen base pair
DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal
Structure 13 (10), 1569-1577, 2005
1552005
Fast native-SAD phasing for routine macromolecular structure determination
T Weinert, V Olieric, S Waltersperger, E Panepucci, L Chen, H Zhang, ...
Nature Methods 12 (2), 131-133, 2015
1442015
Hoogsteen base pair formation promotes synthesis opposite the 1, N 6-ethenodeoxyadenosine lesion by human DNA polymerase ι
DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal
Nature structural & molecular biology 13 (7), 619-625, 2006
1422006
Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response
DT Nair, K Singh, Z Siddiqui, BP Nayak, KVS Rao, DM Salunke
The Journal of Immunology 168 (5), 2371-2382, 2002
1152002
Vitamin B12 may inhibit RNA‐dependent‐RNA polymerase activity of nsp12 from the SARS‐CoV‐2 virus
N Narayanan, DT Nair
IUBMB Life, 2020
842020
Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity
YK Gupta, DT Nair, RP Wharton, AK Aggarwal
Structure 16 (4), 549-557, 2008
832008
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-ι active site
DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal
Structure 14 (4), 749-755, 2006
732006
Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
J Kottur, DT Nair
Nucleic Acids Research, 2018
652018
Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase
DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal
Structure 16 (2), 239-245, 2008
652008
RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state
P Surana, V Satchidanandam, DT Nair
Nucleic acids research 42 (4), 2758-2773, 2014
622014
DNA synthesis across an abasic lesion by human DNA polymerase ι
DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal
Structure 17 (4), 530-537, 2009
462009
A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli
A Sharma, J Kottur, N Narayanan, DT Nair
Nucleic acids research 41 (9), 5104-5114, 2013
452013
Crystal structure of an antibody bound to an immunodominant peptide epitope: novel features in peptide-antibody recognition
DT Nair, K Singh, N Sahu, KVS Rao, DM Salunke
The Journal of Immunology 165 (12), 6949-6955, 2000
452000
Reactive oxygen species play an important role in the bactericidal activity of quinolone antibiotics
J Kottur, DT Nair
Angewandte Chemie 128 (7), 2443-2446, 2016
432016
DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase
DT Nair, RE Johnson, L Prakash, S Prakash, AK Aggarwal
Journal of molecular biology 406 (1), 18-28, 2011
432011
Mimicry of native peptide antigens by the corresponding retro-inverso analogs is dependent on their intrinsic structure and interaction propensities
DT Nair, KJ Kaur, K Singh, P Mukherjee, D Rajagopal, A George, V Bal, ...
The Journal of Immunology 170 (3), 1362-1373, 2003
412003
Structure of the induced antibacterial protein from tasar silkworm, Antheraea mylitta Implications to molecular evolution
D Jain, DT Nair, GJ Swaminathan, EG Abraham, J Nagaraju, DM Salunke
Journal of Biological Chemistry 276 (44), 41377-41382, 2001
412001
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