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Czeslaw Radziejewski
Czeslaw Radziejewski
Associate Director Protein Analytics, AbbVie Bioreserch Center
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Year
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
PC Maisonpierre, C Suri, PF Jones, S Bartunkova, SJ Wiegand, ...
Science 277 (5322), 55-60, 1997
46801997
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
S Davis, TH Aldrich, PF Jones, A Acheson, DL Compton, V Jain, TE Ryan, ...
Cell 87 (7), 1161-1169, 1996
26011996
VEGF-Trap: a VEGF blocker with potent antitumor effects
J Holash, S Davis, N Papadopoulos, SD Croll, L Ho, M Russell, P Boland, ...
Proceedings of the National Academy of Sciences 99 (17), 11393-11398, 2002
21522002
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment
C Cursiefen, L Chen, LP Borges, D Jackson, J Cao, C Radziejewski, ...
The Journal of clinical investigation 113 (7), 1040-1050, 2004
12252004
trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor
SP Squinto, TN Stitt, TH Aldrich, S Davis, SM Blanco, C RadzieJewski, ...
Cell 65 (5), 885-893, 1991
9901991
The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons
PS DiStefano, B Friedman, C Radziejewski, C Alexander, P Boland, ...
Neuron 8 (5), 983-993, 1992
8831992
Agrin acts via a MuSK receptor complex
DJ Glass, DC Bowen, TN Stitt, C Radziejewski, JA Bruno, TE Ryan, ...
Cell 85 (4), 513-523, 1996
8461996
An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors
A Shrivastava, C Radziejewski, E Campbell, L Kovac, M McGlynn, ...
Molecular cell 1 (1), 25-34, 1997
6381997
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
P Lin, JA Buxton, A Acheson, C Radziejewski, PC Maisonpierre, ...
Proceedings of the National Academy of Sciences 95 (15), 8829-8834, 1998
5501998
Cytokine traps: multi-component, high-affinity blockers of cytokine action
AN Economides, LR Carpenter, JS Rudge, V Wong, EM Koehler-Stec, ...
Nature medicine 9 (1), 47-52, 2003
4862003
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering
S Davis, N Papadopoulos, TH Aldrich, PC Maisonpierre, T Huang, ...
Nature structural biology 10 (1), 38-44, 2003
3222003
Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer
RC Robinson, C Radziejewski, DI Stuart, EY Jones
Biochemistry 34 (13), 4139-4146, 1995
1981995
Thrombin induces the release of angiopoietin-1 from platelets
JJ Li, YQ Huang, R Basch, S Karpatkin
Thrombosis and haemostasis 85 (02), 204-206, 2001
1832001
Modification assisted profiling (MAP) methodology
C Radziejewski, E Shi
US Patent App. 10/699,361, 2004
1602004
Ranking the susceptibility of disulfide bonds in human IgG1 antibodies by reduction, differential alkylation, and LC− MS analysis
H Liu, C Chumsae, G Gaza-Bulseco, K Hurkmans, CH Radziejewski
Analytical chemistry 82 (12), 5219-5226, 2010
1572010
The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site
RC Robinson, C Radziejewski, G Spraggon, J Greenwald, MR Kostura, ...
Protein Science 8 (12), 2589-2597, 1999
1391999
Thrombin induces increased expression and secretion of VEGF from human FS4 fibroblasts, DU145 prostate cells and CHRF megakaryocytes
YQ Huang, JJ Li, L Hu, M Lee, S Karpatkin
Thrombosis and haemostasis 86 (10), 1094-1098, 2001
1382001
Increased serum clearance of oligomannose species present on a human IgG1 molecule
L Alessandri, D Ouellette, A Acquah, M Rieser, D LeBlond, M Saltarelli, ...
MAbs 4 (4), 509-520, 2012
1282012
Recombinant human and rat ciliary neurotrophic factors
P Masiakowski, H Liu, C Radziejewski, F Lottspeich, W Oberthuer, ...
Journal of neurochemistry 57 (3), 1003-1012, 1991
1211991
Dimeric structure and conformational stability of brain-derived neurotrophic factor and neurotrophin-3
C Radziejewski, RC Robinson, PS DiStefano, JW Taylor
Biochemistry 31 (18), 4431-4436, 1992
1051992
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