| Platelet-mediated modulation of adaptive immunity: a communication link between innate and adaptive immune compartments BD Elzey, J Tian, RJ Jensen, AK Swanson, JR Lees, SR Lentz, CS Stein, ... Immunity 19 (1), 9-19, 2003 | 529 | 2003 |
| Regional CNS responses to IFN-γ determine lesion localization patterns during EAE pathogenesis JR Lees, PT Golumbek, J Sim, D Dorsey, JH Russell The Journal of experimental medicine 205 (11), 2633-2642, 2008 | 220 | 2008 |
| Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites IA Cockburn, YC Chen, MG Overstreet, JR Lees, N van Rooijen, ... PLoS pathogens 6 (5), e1000877, 2010 | 114 | 2010 |
| IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis EE McCandless, M Budde, JR Lees, D Dorsey, E Lyng, RS Klein The Journal of Immunology 183 (1), 613-620, 2009 | 103 | 2009 |
| Engineered MBP-specific human Tregs ameliorate MOG-induced EAE through IL-2-triggered inhibition of effector T cells YC Kim, AH Zhang, J Yoon, WE Culp, JR Lees, KW Wucherpfennig, ... Journal of autoimmunity 92, 77-86, 2018 | 93 | 2018 |
| Interferon gamma in autoimmunity: A complicated player on a complex stage JR Lees Cytokine 74 (1), 18-26, 2015 | 92 | 2015 |
| Host T cells are the main producers of IL-17 within the central nervous system during initiation of experimental autoimmune encephalomyelitis induced by adoptive transfer of … JR Lees, Y Iwakura, JH Russell The Journal of Immunology 180 (12), 8066-8072, 2008 | 82 | 2008 |
| Generation, persistence and plasticity of CD4 T‐cell memories JR Lees, DL Farber Immunology 130 (4), 463-470, 2010 | 79 | 2010 |
| Myeloid derived suppressor cells in transplantation JR Lees, AM Azimzadeh, JS Bromberg Current opinion in immunology 23 (5), 692-697, 2011 | 67 | 2011 |
| Pulmonary surfactant protein A activates a phosphatidylinositol 3-kinase/calcium signal transduction pathway in human macrophages: participation in the up-regulation of mannose … AA Beharka, JE Crowther, FX McCormack, GM Denning, J Lees, ... The Journal of Immunology 175 (4), 2227-2236, 2005 | 67 | 2005 |
| A little stress is good: IFN-γ, demyelination, and multiple sclerosis JR Lees, AH Cross The Journal of clinical investigation 117 (2), 297-299, 2007 | 64 | 2007 |
| T‐cell recognition of a prostate specific antigen is not sufficient to induce prostate tissue destruction JR Lees, B Charbonneau, JD Hayball, K Diener, M Brown, R Matusik, ... The Prostate 66 (6), 578-590, 2006 | 38 | 2006 |
| Deletion is neither sufficient nor necessary for the induction of peripheral tolerance in mature CD8+ T cells JR Lees, B Charbonneau, AK Swanson, R Jensen, JF Zhang, R Matusik, ... Immunology 117 (2), 248-261, 2006 | 35 | 2006 |
| Immunobiology of transplantation: impact on targets for large and small molecules AM Azimzadeh, JR Lees, Y Ding, JS Bromberg Clinical Pharmacology & Therapeutics 90 (2), 229-242, 2011 | 31 | 2011 |
| CD8+ T cells: The past and future of immune regulation JR Lees Cellular immunology 357, 104212, 2020 | 22 | 2020 |
| RGC-32 promotes Th17 cell differentiation and enhances experimental autoimmune encephalomyelitis V Rus, V Nguyen, A Tatomir, JR Lees, AP Mekala, D Boodhoo, CA Tegla, ... The Journal of Immunology 198 (10), 3869-3877, 2017 | 20 | 2017 |
| Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate induction AA Clark, S Nurmukhambetova, X Li, SD Munger, JR Lees Journal of Leucocyte Biology 100 (4), 699-709, 2016 | 18 | 2016 |
| Encephalitogenic T-cells increase numbers of CNS T-cells regardless of antigen specificity by both increasing T-cell entry and preventing egress JR Lees, J Sim, JH Russell Journal of neuroimmunology 220 (1-2), 10-16, 2010 | 18 | 2010 |
| Endogenous expansion of regulatory T cells leads to long-term islet graft survival in diabetic NOD mice Q Shi, JR Lees, DW Scott, DL Farber, ST Bartlett American Journal of Transplantation 12 (5), 1124-1132, 2012 | 15 | 2012 |
| T-cell trafficking competence is required for CNS invasion JR Lees, AS Archambault, JH Russell Journal of neuroimmunology 177 (1-2), 1-10, 2006 | 14 | 2006 |
John RussellProfessor of Developmental Biology, Washington UniversityVerified email at wustl.edu
