| Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs SR Bacman, SL Williams, M Pinto, S Peralta, CT Moraes Nature medicine 19 (9), 1111-1113, 2013 | 468 | 2013 |
| Unexpected expression of α-and β-globin in mesencephalic dopaminergic neurons and glial cells M Biagioli, M Pinto, D Cesselli, M Zaninello, D Lazarevic, P Roncaglia, ... Proceedings of the National Academy of Sciences 106 (36), 15454-15459, 2009 | 315 | 2009 |
| MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation SR Bacman, JHK Kauppila, CV Pereira, N Nissanka, M Miranda, M Pinto, ... Nature medicine 24 (11), 1696-1700, 2018 | 240 | 2018 |
| Mechanisms linking mtDNA damage and aging M Pinto, CT Moraes Free Radical Biology and Medicine 85, 250-258, 2015 | 214 | 2015 |
| Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease AM Pickrell, M Pinto, A Hida, CT Moraes Journal of Neuroscience 31 (48), 17649-17658, 2011 | 128 | 2011 |
| The striatum is highly susceptible to mitochondrial oxidative phosphorylation dysfunctions AM Pickrell, H Fukui, X Wang, M Pinto, CT Moraes Journal of neuroscience 31 (27), 9895-9904, 2011 | 119 | 2011 |
| TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains S Zucchelli, M Codrich, F Marcuzzi, M Pinto, S Vilotti, M Biagioli, I Ferrer, ... Human molecular genetics 19 (19), 3759-3770, 2010 | 110 | 2010 |
| Mitochondrial genome changes and neurodegenerative diseases M Pinto, CT Moraes Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014 | 93 | 2014 |
| Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation S Zucchelli, F Marcuzzi, M Codrich, E Agostoni, S Vilotti, M Biagioli, ... Journal of Biological Chemistry 286 (28), 25108-25117, 2011 | 75 | 2011 |
| Pioglitazone ameliorates the phenotype of a novel Parkinson’s disease mouse model by reducing neuroinflammation M Pinto, N Nissanka, S Peralta, R Brambilla, F Diaz, CT Moraes Molecular neurodegeneration 11, 1-15, 2016 | 72 | 2016 |
| Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations S Zucchelli, S Vilotti, R Calligaris, ZS Lavina, M Biagioli, R Foti, ... Cell Death & Differentiation 16 (3), 428-438, 2009 | 62 | 2009 |
| Cryptic amyloidogenic elements in the 3′ UTRs of neurofilament genes trigger axonal neuropathy AP Rebelo, AJ Abrams, E Cottenie, A Horga, M Gonzalez, DM Bis, ... The American Journal of Human Genetics 98 (4), 597-614, 2016 | 61 | 2016 |
| Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6 S Vilotti, M Codrich, M Dal Ferro, M Pinto, I Ferrer, L Collavin, S Gustincich, ... PloS one 7 (4), e35051, 2012 | 59 | 2012 |
| Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner M Pinto, AM Pickrell, X Wang, SR Bacman, A Yu, A Hida, LM Dillon, ... Cell Death & Differentiation 24 (2), 288-299, 2017 | 55 | 2017 |
| Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool X Wang, AM Pickrell, SG Rossi, M Pinto, LM Dillon, A Hida, RL Rotundo, ... Human molecular genetics 22 (19), 3976-3986, 2013 | 54 | 2013 |
| Lack of Parkin anticipates the phenotype and affects mitochondrial morphology and mtDNA levels in a mouse model of Parkinson's disease M Pinto, N Nissanka, CT Moraes Journal of Neuroscience 38 (4), 1042-1053, 2018 | 53 | 2018 |
| The use of mitochondria-targeted endonucleases to manipulate mtDNA SR Bacman, SL Williams, M Pinto, CT Moraes Methods in enzymology 547, 373-397, 2014 | 51 | 2014 |
| Mitochondrial DNA double-strand breaks in oligodendrocytes cause demyelination, axonal injury, and CNS inflammation PM Madsen, M Pinto, S Patel, S McCarthy, H Gao, M Taherian, S Karmally, ... Journal of Neuroscience 37 (42), 10185-10199, 2017 | 46 | 2017 |
| Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formation M Pinto, AM Pickrell, H Fukui, CT Moraes Neurobiology of aging 34 (10), 2399-2407, 2013 | 46 | 2013 |
| Intravenous administration of mesenchymal stem cells reduces Tau phosphorylation and inflammation in the 3xTg-AD mouse model of Alzheimer's disease AF Neves, C Camargo, C Premer, JM Hare, BS Baumel, M Pinto Experimental neurology 341, 113706, 2021 | 37 | 2021 |
