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Samuel Schmitz
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Rosetta: MSF: a modular framework for multi-state computational protein design
P Löffler, S Schmitz, E Hupfeld, R Sterner, R Merkl
PLoS computational biology 13 (6), e1005600, 2017
482017
Modeling immunity with rosetta: Methods for antibody and antigen design
CT Schoeder, S Schmitz, J Adolf-Bryfogle, AM Sevy, JA Finn, MF Sauer, ...
Biochemistry 60 (11), 825-846, 2021
312021
Plasmodium falciparum Nucleosomes Exhibit Reduced Stability and Lost Sequence Dependent Nucleosome Positioning
E Silberhorn, U Schwartz, P Löffler, S Schmitz, A Symelka, ...
PLoS pathogens 12 (12), e1006080, 2016
292016
Identification of a novel leptin receptor (LEPR) variant and proof of functional relevance directing treatment decisions in patients with morbid obesity
F Voigtmann, P Wolf, K Landgraf, R Stein, J Kratzsch, S Schmitz, ...
Metabolism 116, 154438, 2021
222021
PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST
C Soto, JA Finn, JR Willis, SB Day, RS Sinkovits, T Jones, S Schmitz, ...
BMC bioinformatics 21, 1-7, 2020
212020
Rosetta design with co-evolutionary information retains protein function
S Schmitz, M Ertelt, R Merkl, J Meiler
PLoS Computational Biology 17 (1), e1008568, 2021
132021
Human-likeness of antibody biologics determined by back-translation and comparison with large antibody variable gene repertoires
S Schmitz, C Soto, JE Crowe Jr, J Meiler
MAbs 12 (1), 1758291, 2020
92020
RosettaCM for antibodies with very long HCDR3s and low template availability
P Kodali, CT Schoeder, S Schmitz, JE Crowe, J Meiler
Proteins: Structure, Function, and Bioinformatics 89 (11), 1458-1472, 2021
32021
The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta
S Schmitz, EA Schmitz, JE Crowe Jr, J Meiler
Mabs 14 (1), 2068212, 2022
22022
Small integral membrane protein 10 like 1 downregulation enhances differentiation of adipose progenitor cells
M Nebe, S Kehr, S Schmitz, J Breitfeld, J Lorenz, D Le Duc, PF Stadler, ...
Biochemical and biophysical research communications 604, 57-62, 2022
12022
A Modular Framework to Extend Rosetta Protocols with Multistate Design
P Löffler, S Schmitz, E Hupfeld, R Merkl
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Articles 1–11