| DNA as a target for anticancer compounds: methods to determine the mode of binding and the mechanism of action R Palchaudhuri, PJ Hergenrother Current opinion in biotechnology 18 (6), 497-503, 2007 | 797 | 2007 |
| Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells C Granchi, S Roy, C Giacomelli, M Macchia, T Tuccinardi, A Martinelli, ... Journal of medicinal chemistry 54 (6), 1599-1612, 2011 | 256 | 2011 |
| Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin R Palchaudhuri, B Saez, J Hoggatt, A Schajnovitz, DB Sykes, TA Tate, ... Nature biotechnology 34 (7), 738, 2016 | 222 | 2016 |
| Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1 G Schiroli, S Ferrari, A Conway, A Jacob, V Capo, L Albano, T Plati, ... Science Translational Medicine 9 (411), eaan0820, 2017 | 212 | 2017 |
| The complex role of the triphenylmethyl motif in anticancer compounds R Palchaudhuri, V Nesterenko, PJ Hergenrother Journal of the American Chemical Society 130 (31), 10274-10281, 2008 | 168 | 2008 |
| Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation A Czechowicz, R Palchaudhuri, A Scheck, Y Hu, J Hoggatt, B Saez, ... Nature Communications 10 (1), 617, 2019 | 152 | 2019 |
| N-((1-benzyl-1H-1, 2, 3-triazol-4-yl) methyl) arylamide as a new scaffold that provides rapid access to antimicrotubule agents: synthesis and evaluation of antiproliferative … JA Stefely, R Palchaudhuri, PA Miller, RJ Peterson, GC Moraski, ... Journal of medicinal chemistry 53 (8), 3389, 2010 | 138 | 2010 |
| Chemistry and biology of deoxynyboquinone, a potent inducer of cancer cell death JS Bair, R Palchaudhuri, PJ Hergenrother Journal of the American Chemical Society 132 (15), 5469-5478, 2010 | 106 | 2010 |
| A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed R Palchaudhuri, MJ Lambrecht, RC Botham, KC Partlow, TJ Van Ham, ... Cell reports 13 (9), 2027-2036, 2015 | 86 | 2015 |
| Dual Targeting of the Warburg Effect with a Glucose‐Conjugated Lactate Dehydrogenase Inhibitor EC Calvaresi, C Granchi, T Tuccinardi, V Di Bussolo, RW Huigens III, ... ChemBioChem 14 (17), 2263-2267, 2013 | 59 | 2013 |
| Differential effects of procaspase-3 activating compounds in the induction of cancer cell death DC West, Y Qin, QP Peterson, DL Thomas, R Palchaudhuri, KC Morrison, ... Molecular pharmaceutics 9 (5), 1425, 2012 | 51 | 2012 |
| Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning B Saez, F Ferraro, RZ Yusuf, CM Cook, WC Vionnie, A Pardo-Saganta, ... Blood 124 (19), 2937-2947, 2014 | 49 | 2014 |
| Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning. B Saez, F Ferraro, RZ Yusuf, CM Cook, VW Yu, A Pardo-Saganta, ... Blood 124 (19), 2937-2947, 2014 | 49 | 2014 |
| Transcript profiling and RNA interference as tools to identify small molecule mechanisms and therapeutic potential R Palchaudhuri, PJ Hergenrother ACS chemical biology 6 (1), 21, 2011 | 40 | 2011 |
| Cribrostatin 6 induces death in cancer cells through a reactive oxygen species (ROS)-mediated mechanism MT Hoyt, R Palchaudhuri, PJ Hergenrother Investigational new drugs 29 (4), 562-573, 2011 | 37 | 2011 |
| Efficacy and safety of anti-CD45-Saporin as conditioning agent for RAG deficiency MC Castiello, M Bosticardo, E Calzoni, E Fontana, Y Yamazaki, ... Journal of Allergy and Clinical Immunology, 2020 | 33 | 2020 |
| Triphenylmethylamides (TPMAs): Structure–activity relationship of compounds that induce apoptosis in melanoma cells R Palchaudhuri, PJ Hergenrother Bioorganic & medicinal chemistry letters 18 (22), 5888-5891, 2008 | 25 | 2008 |
| Effective multi-lineage engraftment in a mouse model of Fanconi anemia using non-genotoxic antibody-based conditioning MA Srikanthan, O Humbert, KG Haworth, C Ironside, YS Rajawat, ... Molecular Therapy-Methods & Clinical Development, 2020 | 23 | 2020 |
| 1 J WSn as a Solution State Predictor for Tungsten-Tin Solid State Bond Length in Sterically Crowded Tungstenocene Stannyl Complexes TA Mobley, R Gandour, EP Gillis, K Nti-Addae, R Palchaudhuri, ... Organometallics 24 (16), 3897-3906, 2005 | 18 | 2005 |
| CD117-Amanitin Antibody Drug Conjugates Effectively Deplete Human and Non-Human Primate HSCs: Proof of Concept As a Targeted Strategy for Conditioning Patients for Bone Marrow … BR Pearse, SM McDonough, JL Proctor, R Panwar, G Sarma, MA McShea, ... Blood 132 (Suppl 1), 3314-3314, 2018 | 16 | 2018 |
Paul J. HergenrotherProfessor of Chemistry, University of IllinoisVerified email at uiuc.edu
