| Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL KG Roberts, YL Yang, D Payne-Turner, W Lin, JK Files, K Dickerson, Z Gu, ... Blood advances 1 (20), 1657-1671, 2017 | 133 | 2017 |
| A phosphotyrosine switch regulates organic cation transporters JA Sprowl, SS Ong, AA Gibson, S Hu, G Du, W Lin, L Li, S Bharill, ... Nature communications 7 (1), 10880, 2016 | 125 | 2016 |
| Cyclin-dependent kinase 2 negatively regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cells W Lin, J Wu, H Dong, D Bouck, FY Zeng, T Chen Journal of biological chemistry 283 (45), 30650-30657, 2008 | 116 | 2008 |
| SPA70 is a potent antagonist of human pregnane X receptor W Lin, YM Wang, SC Chai, L Lv, J Zheng, J Wu, Q Zhang, YD Wang, ... Nature communications 8 (1), 741, 2017 | 95 | 2017 |
| Flavonoids activate pregnane × receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells H Dong, W Lin, J Wu, T Chen BMC biochemistry 11, 1-9, 2010 | 89 | 2010 |
| Identification of small molecule activators of BMP signaling K Vrijens, W Lin, J Cui, D Farmer, J Low, E Pronier, FY Zeng, AA Shelat, ... PloS one 8 (3), e59045, 2013 | 87 | 2013 |
| Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1 YM Wang, W Lin, SC Chai, J Wu, SS Ong, EG Schuetz, T Chen Toxicology and applied pharmacology 272 (1), 96-107, 2013 | 79 | 2013 |
| A tea catechin, epigallocatechin-3-gallate, is a unique modulator of the farnesoid X receptor G Li, W Lin, JJ Araya, T Chen, BN Timmermann, GL Guo Toxicology and applied pharmacology 258 (2), 268-274, 2012 | 73 | 2012 |
| Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation WH Leung, QP Vong, W Lin, L Janke, T Chen, W Leung Journal of Experimental Medicine 210 (12), 2675-2692, 2013 | 68 | 2013 |
| Modulation of pantothenate kinase 3 activity by small molecules that interact with the substrate/allosteric regulatory domain R Leonardi, YM Zhang, MK Yun, R Zhou, FY Zeng, W Lin, J Cui, T Chen, ... Chemistry & biology 17 (8), 892-902, 2010 | 57 | 2010 |
| CINPA1 is an inhibitor of constitutive androstane receptor that does not activate pregnane X receptor MT Cherian, W Lin, J Wu, T Chen Molecular Pharmacology 87 (5), 878-889, 2015 | 53 | 2015 |
| Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine … C Wang, W Lin, H Playa, S Sun, K Cameron, JK Buolamwini Biochemical pharmacology 86 (11), 1531-1540, 2013 | 50 | 2013 |
| Targeting histone demethylases in MYC-driven neuroblastomas with ciclopirox J Yang, S Milasta, D Hu, AM AlTahan, RB Interiano, J Zhou, J Davidson, ... Cancer research 77 (17), 4626-4638, 2017 | 48 | 2017 |
| Metabolic activation of CaMKII by coenzyme A F McCoy, R Darbandi, HC Lee, K Bharatham, T Moldoveanu, CR Grace, ... Molecular cell 52 (3), 325-339, 2013 | 45 | 2013 |
| Synthesis of a peptidomimetic HCMV protease inhibitor library P Xu, W Lin, X Zou Synthesis 2002 (08), 1017-1026, 2002 | 39 | 2002 |
| Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma C He, K Xu, X Zhu, PS Dunphy, B Gudenas, W Lin, N Twarog, LD Hover, ... Nature communications 12 (1), 4089, 2021 | 37 | 2021 |
| Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor DY Donna, W Lin, BM Forman, T Chen Bioorganic & medicinal chemistry 22 (11), 2919-2938, 2014 | 37 | 2014 |
| Ventromorphins: A new class of small molecule activators of the canonical BMP signaling pathway JR Genthe, J Min, DM Farmer, AA Shelat, JA Grenet, W Lin, D Finkelstein, ... ACS chemical biology 12 (9), 2436-2447, 2017 | 34 | 2017 |
| An unexpected protein interaction promotes drug resistance in leukemia A Pitre, Y Ge, W Lin, Y Wang, Y Fukuda, J Temirov, AH Phillips, JL Peters, ... Nature communications 8 (1), 1547, 2017 | 30 | 2017 |
| PRL-3 mediates the protein maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60 WH Leung, QP Vong, W Lin, D Bouck, S Wendt, E Sullivan, Y Li, R Bari, ... The Journal of Immunology 194 (6), 2930-2941, 2015 | 30 | 2015 |
Richard E. LeeMember, St Jude Children's Research HospitalVerified email at stjude.org
