Elucidation of a universal size-control mechanism in Drosophila and mammals J Dong, G Feldmann, J Huang, S Wu, N Zhang, SA Comerford, ... Cell 130 (6), 1120-1133, 2007 | 2506 | 2007 |
The hippo signaling pathway in development and cancer D Pan Developmental cell 19 (4), 491-505, 2010 | 2406 | 2010 |
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP J Huang, S Wu, J Barrera, K Matthews, D Pan Cell 122 (3), 421-434, 2005 | 1925 | 2005 |
Genetic and pharmacological disruption of the TEAD–YAP complex suppresses the oncogenic activity of YAP Y Liu-Chittenden, B Huang, JS Shim, Q Chen, SJ Lee, RA Anders, JO Liu, ... Genes & development 26 (12), 1300-1305, 2012 | 1362 | 2012 |
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts S Wu, J Huang, J Dong, D Pan Cell 114 (4), 445-456, 2003 | 1207 | 2003 |
A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1 JS Mumm, EH Schroeter, MT Saxena, A Griesemer, X Tian, DJ Pan, ... Molecular cell 5 (2), 197-206, 2000 | 1121 | 2000 |
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins Y Zhang, X Gao, LJ Saucedo, B Ru, BA Edgar, D Pan Nature cell biology 5 (6), 578-581, 2003 | 1099 | 2003 |
Tsc tumour suppressor proteins antagonize amino-acid–TOR signalling X Gao, Y Zhang, P Arrazola, O Hino, T Kobayashi, RS Yeung, B Ru, ... Nature cell biology 4 (9), 699-704, 2002 | 836 | 2002 |
Rheb promotes cell growth as a component of the insulin/TOR signalling network LJ Saucedo, X Gao, DA Chiarelli, L Li, D Pan, BA Edgar Nature cell biology 5 (6), 566-571, 2003 | 813 | 2003 |
The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals N Zhang, H Bai, KK David, J Dong, Y Zheng, J Cai, M Giovannini, P Liu, ... Developmental cell 19 (1), 27-38, 2010 | 811 | 2010 |
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-β pathways C Alarcón, AI Zaromytidou, Q Xi, S Gao, J Yu, S Fujisawa, A Barlas, ... Cell 139 (4), 757-769, 2009 | 793 | 2009 |
Hippo signaling in organ size control D Pan Genes & development 21 (8), 886-897, 2007 | 744 | 2007 |
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway S Wu, Y Liu, Y Zheng, J Dong, D Pan Developmental cell 14 (3), 388-398, 2008 | 685 | 2008 |
Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis D Pan, GM Rubin Cell 90 (2), 271-280, 1997 | 672 | 1997 |
Expression of Yes-associated protein in common solid tumors AA Steinhardt, MF Gayyed, AP Klein, J Dong, A Maitra, D Pan, ... Human pathology 39 (11), 1582-1589, 2008 | 661 | 2008 |
The Hippo signaling pathway in development and disease Y Zheng, D Pan Developmental cell 50 (3), 264-282, 2019 | 574 | 2019 |
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth X Gao, D Pan Genes & development 15 (11), 1383-1392, 2001 | 564 | 2001 |
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded J Yu, Y Zheng, J Dong, S Klusza, WM Deng, D Pan Developmental cell 18 (2), 288-299, 2010 | 550 | 2010 |
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program J Cai, N Zhang, Y Zheng, RF De Wilde, A Maitra, D Pan Genes & development 24 (21), 2383-2388, 2010 | 538 | 2010 |
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2 F Yin, J Yu, Y Zheng, Q Chen, N Zhang, D Pan Cell 154 (6), 1342-1355, 2013 | 526 | 2013 |