| Altered P2X7‐receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration M Díaz-Hernández, M Díez-Zaera, J Sánchez-Nogueiro, ... The FASEB Journal 23 (6), 1893-1906, 2009 | 269 | 2009 |
| Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice T Engel, R Gomez‐Villafuertes, K Tanaka, G Mesuret, A Sanz‐Rodriguez, ... The FASEB journal 26 (4), 1616-1628, 2012 | 218 | 2012 |
| In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases JI Diaz-Hernandez, R Gomez-Villafuertes, M León-Otegui, ... Neurobiology of aging 33 (8), 1816-1828, 2012 | 213 | 2012 |
| Ca2+-Operated Transcriptional Networks: Molecular Mechanisms and In Vivo Models B Mellstrom, M Savignac, R Gomez-Villafuertes, JR Naranjo Physiological reviews 88 (2), 421-449, 2008 | 191 | 2008 |
| Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau M Díaz-Hernández, A Gómez-Ramos, A Rubio, R Gómez-Villafuertes, ... Journal of Biological Chemistry 285 (42), 32539-32548, 2010 | 175 | 2010 |
| P2X7 Receptors in Rat Brain: Presence in Synaptic Terminals and Granule Cells MT Miras-Portugal, M Díaz-Hernández, L Giráldez, C Hervás, ... Neurochemical research 28, 1597-1605, 2003 | 125 | 2003 |
| Diadenosine polyphosphate receptors: from rat and guinea-pig brain to human nervous system J Pintor, M Dı́az-Hernández, J Gualix, R Gómez-Villafuertes, F Hernando, ... Pharmacology & therapeutics 87 (2-3), 103-115, 2000 | 115 | 2000 |
| Downstream regulatory element antagonist modulator regulates Ca2+ homeostasis and viability in cerebellar neurons R Gomez-Villafuertes, B Torres, J Barrio, M Savignac, N Gabellini, ... Journal of Neuroscience 25 (47), 10822-10830, 2005 | 109 | 2005 |
| Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation A del Puerto, JI Díaz-Hernández, M Tapia, R Gomez-Villafuertes, ... Journal of cell science 125 (1), 176-188, 2012 | 103 | 2012 |
| Ca2+/calmodulin‐dependent kinase II signalling cascade mediates P2X7 receptor‐dependent inhibition of neuritogenesis in neuroblastoma cells R Gómez‐Villafuertes, A del Puerto, M Díaz‐Hernández, D Bustillo, ... The FEBS journal 276 (18), 5307-5325, 2009 | 93 | 2009 |
| PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions R Gómez-Villafuertes, P García-Huerta, JI Díaz-Hernández, ... Scientific reports 5 (1), 18417, 2015 | 80 | 2015 |
| Single GABAergic synaptic terminals from rat midbrain exhibit functional P2X and dinucleotide receptors, able to induce GABA secretion R Gómez‐Villafuertes, J Gualix, MT Miras‐Portugal Journal of neurochemistry 77 (1), 84-93, 2001 | 77 | 2001 |
| Nucleotides in neuroregeneration and neuroprotection MT Miras-Portugal, R Gomez-Villafuertes, J Gualix, JI Diaz-Hernandez, ... Neuropharmacology 104, 243-254, 2016 | 74 | 2016 |
| Opposite effects of P2X7 and P2Y2 nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells M León-Otegui, R Gómez-Villafuertes, JI Díaz-Hernández, ... FEBS letters 585 (14), 2255-2262, 2011 | 70 | 2011 |
| P2X7 receptors trigger ATP exocytosis and modify secretory vesicle dynamics in neuroblastoma cells Y Gutierrez-Martin, D Bustillo, R Gómez-Villafuertes, J Sánchez-Nogueiro, ... Journal of Biological Chemistry 286 (13), 11370-11381, 2011 | 69 | 2011 |
| The specificity protein factor Sp1 mediates transcriptional regulation of P2X7 receptors in the nervous system P García-Huerta, M Díaz-Hernandez, EG Delicado, M Pimentel-Santillana, ... Journal of Biological Chemistry 287 (53), 44628-44644, 2012 | 68 | 2012 |
| Diadenosine polyphosphates, extracellular function and catabolism MT Miras-Portugal, J Gualix, J Mateo, M Díaz-Hernández, ... Progress in brain research 120, 397-409, 1999 | 60 | 1999 |
| Diadenosine polyphosphates, extracellular function and catabolism MT Miras-Portugal, J Gualix, J Mateo, M Díaz-Hernández, ... Progress in brain research 120, 397-409, 1999 | 60 | 1999 |
| Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug‐refractory epilepsy M Alves, R Gomez‐Villafuertes, N Delanty, MA Farrell, DF O'Brien, ... Epilepsia 58 (9), 1603-1614, 2017 | 57 | 2017 |
| Synaptic terminals from mice midbrain exhibit functional P2X7 receptor P Marín-García, J Sánchez-Nogueiro, R Gómez-Villafuertes, D León, ... Neuroscience 151 (2), 361-373, 2008 | 55 | 2008 |
Miras-Portugal MT.Professor of Biochemistry and Molecular Biology, Universidad Complutense de Madrid. Member of theVerified email at vet.ucm.es
