Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the atypical receptor ACKR1 determine discrete stages of neutrophil diapedesis T Girbl, T Lenn, L Perez, L Rolas, A Barkaway, A Thiriot, C Del Fresno, ... Immunity 49 (6), 1062-1076. e6, 2018 | 287 | 2018 |
NADPH oxidase activation in neutrophils: Role of the phosphorylation of its subunits SA Belambri, L Rolas, H Raad, M Hurtado‐Nedelec, PMC Dang, ... European journal of clinical investigation 48, e12951, 2018 | 241 | 2018 |
Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome O Santiago-Fernández, FG Osorio, V Quesada, F Rodríguez, S Basso, ... Nature Medicine, 2019 | 150 | 2019 |
Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage A Barkaway, L Rolas, R Joulia, J Bodkin, T Lenn, C Owen-Woods, ... Immunity 54 (7), 1494-1510. e7, 2021 | 78 | 2021 |
Impaired intracellular signaling, myeloperoxidase release and bactericidal activity of neutrophils from patients with alcoholic cirrhosis A Boussif, L Rolas, E Weiss, H Bouriche, R Moreau, A Périanin Journal of hepatology 64 (5), 1041-1048, 2016 | 66 | 2016 |
Local microvascular leakage promotes trafficking of activated neutrophils to remote organs C Owen-Woods, R Joulia, A Barkaway, L Rolas, B Ma, AF Nottebaum, ... The Journal of clinical investigation 130 (5), 2301-2318, 2020 | 59 | 2020 |
Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation N Reglero-Real, L Pérez-Gutiérrez, A Yoshimura, L Rolas, ... Immunity 54 (9), 1989-2004. e9, 2021 | 53 | 2021 |
Inhibition of mammalian target of rapamycin aggravates the respiratory burst defect of neutrophils from decompensated patients with cirrhosis L Rolas, N Makhezer, S Hadjoudj, J El‐Benna, B Djerdjouri, L Elkrief, ... Hepatology 57 (3), 1163-1171, 2013 | 51 | 2013 |
NADPH oxidase depletion in neutrophils from patients with cirrhosis and restoration via toll-like receptor 7/8 activation L Rolas, A Boussif, E Weiss, P Lettéron, O Haddad, J El-Benna, ... Gut 67 (8), 1505-1516, 2018 | 39 | 2018 |
The dual role of reactive oxygen species-generating nicotinamide adenine dinucleotide phosphate oxidases in gastrointestinal inflammation and therapeutic perspectives PMC Dang, L Rolas, J El-Benna Antioxidants & redox signaling 33 (5), 354-373, 2020 | 28 | 2020 |
Cardiovascular progerin suppression and lamin A restoration rescue Hutchinson-Gilford progeria syndrome A Sánchez-López, C Espinós-Estévez, C González-Gómez, P Gonzalo, ... Circulation 144 (22), 1777-1794, 2021 | 24 | 2021 |
Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment LC Madjene, L Danelli, A Dahdah, S Vibhushan, J Bex-Coudrat, ... Kidney international 97 (3), 516-527, 2020 | 21 | 2020 |
Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome B Marcos-Ramiro, A Gil-Ordóñez, NI Marín-Ramos, FJ Ortega-Nogales, ... ACS Central Science 7 (8), 1300-1310, 2021 | 20 | 2021 |
Leukocyte trafficking: time to take time seriously N Reglero-Real, L Rolas, S Nourshargh Immunity 50 (2), 273-275, 2019 | 14 | 2019 |
The dual role of ROS-generating NADPH oxidases in gastrointestinal inflammation and therapeutic perspectives PMC Dang, L Rolas, J El Benna Antioxidants and Redox Signaling 33 (5), 354-373, 2020 | 5 | 2020 |
The Kinesin Light Chain–Related Protein PAT1 Promotes Superoxide Anion Production in Human Phagocytes R Arabi-Derkawi, Y O’dowd, N Cheng, L Rolas, T Boussetta, H Raad, ... The Journal of Immunology 202 (5), 1549-1558, 2019 | 1 | 2019 |
Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells I Benedicto, RM Carmona, A Barettino, C Espinós-Estévez, P Gonzalo, ... Proceedings of the National Academy of Sciences 121 (18), e2400752121, 2024 | | 2024 |
Suggested searches Y Gong, Z Wang, W Zong, R Shi, W Sun, S Wang, B Peng, S Takeda, X Xu, ... Perspective, 2023 | | 2023 |
Delayed localization of A-type lamins to the rupture sites in Hutchinson–Gilford progeria syndrome Y Kono, CG Pack, T Ichikawa, A Komatsubara, SA Adam, K Miyazawa, ... bioRxiv, 2023.09. 02.555826, 2023 | | 2023 |
Tlr7 and/or tlr8 agonists for the treatment of bacterial infections in patients suffering from cirrhosis AJ PERIANIN, L ROLAS | | 2021 |