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Loïc Rolas
Loïc Rolas
Adresse e-mail validée de qmul.ac.uk
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Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the atypical receptor ACKR1 determine discrete stages of neutrophil diapedesis
T Girbl, T Lenn, L Perez, L Rolas, A Barkaway, A Thiriot, C Del Fresno, ...
Immunity 49 (6), 1062-1076. e6, 2018
2872018
NADPH oxidase activation in neutrophils: Role of the phosphorylation of its subunits
SA Belambri, L Rolas, H Raad, M Hurtado‐Nedelec, PMC Dang, ...
European journal of clinical investigation 48, e12951, 2018
2412018
Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome
O Santiago-Fernández, FG Osorio, V Quesada, F Rodríguez, S Basso, ...
Nature Medicine, 2019
1502019
Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage
A Barkaway, L Rolas, R Joulia, J Bodkin, T Lenn, C Owen-Woods, ...
Immunity 54 (7), 1494-1510. e7, 2021
782021
Impaired intracellular signaling, myeloperoxidase release and bactericidal activity of neutrophils from patients with alcoholic cirrhosis
A Boussif, L Rolas, E Weiss, H Bouriche, R Moreau, A Périanin
Journal of hepatology 64 (5), 1041-1048, 2016
662016
Local microvascular leakage promotes trafficking of activated neutrophils to remote organs
C Owen-Woods, R Joulia, A Barkaway, L Rolas, B Ma, AF Nottebaum, ...
The Journal of clinical investigation 130 (5), 2301-2318, 2020
592020
Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation
N Reglero-Real, L Pérez-Gutiérrez, A Yoshimura, L Rolas, ...
Immunity 54 (9), 1989-2004. e9, 2021
532021
Inhibition of mammalian target of rapamycin aggravates the respiratory burst defect of neutrophils from decompensated patients with cirrhosis
L Rolas, N Makhezer, S Hadjoudj, J El‐Benna, B Djerdjouri, L Elkrief, ...
Hepatology 57 (3), 1163-1171, 2013
512013
NADPH oxidase depletion in neutrophils from patients with cirrhosis and restoration via toll-like receptor 7/8 activation
L Rolas, A Boussif, E Weiss, P Lettéron, O Haddad, J El-Benna, ...
Gut 67 (8), 1505-1516, 2018
392018
The dual role of reactive oxygen species-generating nicotinamide adenine dinucleotide phosphate oxidases in gastrointestinal inflammation and therapeutic perspectives
PMC Dang, L Rolas, J El-Benna
Antioxidants & redox signaling 33 (5), 354-373, 2020
282020
Cardiovascular progerin suppression and lamin A restoration rescue Hutchinson-Gilford progeria syndrome
A Sánchez-López, C Espinós-Estévez, C González-Gómez, P Gonzalo, ...
Circulation 144 (22), 1777-1794, 2021
242021
Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment
LC Madjene, L Danelli, A Dahdah, S Vibhushan, J Bex-Coudrat, ...
Kidney international 97 (3), 516-527, 2020
212020
Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome
B Marcos-Ramiro, A Gil-Ordóñez, NI Marín-Ramos, FJ Ortega-Nogales, ...
ACS Central Science 7 (8), 1300-1310, 2021
202021
Leukocyte trafficking: time to take time seriously
N Reglero-Real, L Rolas, S Nourshargh
Immunity 50 (2), 273-275, 2019
142019
The dual role of ROS-generating NADPH oxidases in gastrointestinal inflammation and therapeutic perspectives
PMC Dang, L Rolas, J El Benna
Antioxidants and Redox Signaling 33 (5), 354-373, 2020
52020
The Kinesin Light Chain–Related Protein PAT1 Promotes Superoxide Anion Production in Human Phagocytes
R Arabi-Derkawi, Y O’dowd, N Cheng, L Rolas, T Boussetta, H Raad, ...
The Journal of Immunology 202 (5), 1549-1558, 2019
12019
Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells
I Benedicto, RM Carmona, A Barettino, C Espinós-Estévez, P Gonzalo, ...
Proceedings of the National Academy of Sciences 121 (18), e2400752121, 2024
2024
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Y Gong, Z Wang, W Zong, R Shi, W Sun, S Wang, B Peng, S Takeda, X Xu, ...
Perspective, 2023
2023
Delayed localization of A-type lamins to the rupture sites in Hutchinson–Gilford progeria syndrome
Y Kono, CG Pack, T Ichikawa, A Komatsubara, SA Adam, K Miyazawa, ...
bioRxiv, 2023.09. 02.555826, 2023
2023
Tlr7 and/or tlr8 agonists for the treatment of bacterial infections in patients suffering from cirrhosis
AJ PERIANIN, L ROLAS
2021
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