Cancer-associated fibroblasts in gastrointestinal cancer H Kobayashi, A Enomoto, SL Woods, AD Burt, M Takahashi, DL Worthley Nature reviews Gastroenterology & hepatology 16 (5), 282-295, 2019 | 434 | 2019 |
Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis Y Mizutani, H Kobayashi, T Iida, N Asai, A Masamune, A Hara, N Esaki, ... Cancer research 79 (20), 5367-5381, 2019 | 239 | 2019 |
Medium-throughput drug screening of patient-derived organoids from colorectal peritoneal metastases to direct personalized therapy V Narasimhan, JA Wright, M Churchill, T Wang, R Rosati, TRM Lannagan, ... Clinical Cancer Research 26 (14), 3662-3670, 2020 | 123 | 2020 |
Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis TRM Lannagan, YK Lee, T Wang, J Roper, ML Bettington, L Fennell, ... Gut 68 (4), 684-692, 2019 | 107 | 2019 |
The balance of stromal BMP signaling mediated by GREM1 and ISLR drives colorectal carcinogenesis H Kobayashi, KA Gieniec, JA Wright, T Wang, N Asai, Y Mizutani, T Lida, ... Gastroenterology 160 (4), 1224-1239. e30, 2021 | 92 | 2021 |
The origin and contribution of cancer-associated fibroblasts in colorectal carcinogenesis H Kobayashi, KA Gieniec, TRM Lannagan, T Wang, N Asai, Y Mizutani, ... Gastroenterology 162 (3), 890-906, 2022 | 85 | 2022 |
Roles of the mesenchymal stromal/stem cell marker meflin in cardiac tissue repair and the development of diastolic dysfunction A Hara, H Kobayashi, N Asai, S Saito, T Higuchi, K Kato, T Okumura, ... Circulation research 125 (4), 414-430, 2019 | 59 | 2019 |
GPR34 in spinal microglia exacerbates neuropathic pain in mice A Sayo, H Konishi, M Kobayashi, K Kano, H Kobayashi, H Hibi, J Aoki, ... Journal of Neuroinflammation 16, 1-11, 2019 | 43 | 2019 |
Roles of the mesenchymal stromal/stem cell marker Meflin/Islr in cancer fibrosis M Takahashi, H Kobayashi, Y Mizutani, A Hara, T Iida, Y Miyai, N Asai, ... Frontiers in Cell and Developmental Biology 9, 749924, 2021 | 30 | 2021 |
Connective tissue growth factor produced by cancer‑associated fibroblasts correlates with poor prognosis in epithelioid malignant pleural mesothelioma Y Ohara, A Enomoto, Y Tsuyuki, K Sato, T Iida, H Kobayashi, Y Mizutani, ... Oncology reports 44 (3), 838-848, 2020 | 27 | 2020 |
Essential role of linx/Islr2 in the development of the forebrain anterior commissure S Abudureyimu, N Asai, A Enomoto, L Weng, H Kobayashi, X Wang, ... Scientific reports 8 (1), 7292, 2018 | 22 | 2018 |
The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota SJ Blake, J James, FJ Ryan, J Caparros-Martin, GL Eden, YC Tee, ... Cell Reports Medicine 2 (12), 2021 | 20 | 2021 |
Meflin-positive cancer-associated fibroblasts enhance tumor response to immune checkpoint blockade Y Miyai, D Sugiyama, T Hase, N Asai, T Taki, K Nishida, T Fukui, ... Life Science Alliance 5 (6), 2022 | 16 | 2022 |
Specific regulation of BACH1 by the hotspot mutant p53R175H reveals a distinct gain-of-function mechanism Z Su, N Kon, J Yi, H Zhao, W Zhang, Q Tang, H Li, H Kobayashi, Z Li, ... Nature cancer 4 (4), 564-581, 2023 | 13 | 2023 |
Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity A Hara, K Kato, T Ishihara, H Kobayashi, N Asai, S Mii, Y Shiraki, Y Miyai, ... Genes to Cells 26 (7), 495-512, 2021 | 13 | 2021 |
The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses M Ichinose, N Suzuki, T Wang, H Kobayashi, L Vrbanac, JQ Ng, JA Wright, ... Development 148 (14), dev195883, 2021 | 10 | 2021 |
A novel renal perivascular mesenchymal cell subset gives rise to fibroblasts distinct from classic myofibroblasts S Minatoguchi, S Saito, K Furuhashi, Y Sawa, M Okazaki, Y Shimamura, ... Scientific reports 12 (1), 5389, 2022 | 8 | 2022 |
Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development M Ichinose, N Suzuki, T Wang, JA Wright, TRM Lannagan, L Vrbanac, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 320 (4 …, 2021 | 6 | 2021 |
Colorectal cancer detection and treatment with engineered probiotics CR Gurbatri, G Radford, L Vrbanac, C Coker, J Im, SR Taylor, YU Jang, ... bioRxiv, 2023.04. 03.535370, 2023 | 3 | 2023 |
Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia CR Gurbatri, GA Radford, L Vrbanac, J Im, EM Thomas, C Coker, ... Nature Communications 15 (1), 646, 2024 | 2 | 2024 |