Oxidative guanine base damage regulates human telomerase activity E Fouquerel, J Lormand, A Bose, HT Lee, GS Kim, J Li, RW Sobol, ... Nature structural & molecular biology 23 (12), 1092-1100, 2016 | 167 | 2016 |
Proteomic profiling reveals a specific role for translesion DNA polymerase η in the alternative lengthening of telomeres L Garcia-Exposito, E Bournique, V Bergoglio, A Bose, J Barroso-Gonzalez, ... Cell reports 17 (7), 1858-1871, 2016 | 139 | 2016 |
PDX-derived organoids model in vivo drug response and secrete biomarkers L Huang, B Bockorny, I Paul, D Akshinthala, PO Frappart, O Gandarilla, ... JCI insight 5 (21), 2020 | 76 | 2020 |
Molecular mechanisms by which oxidative DNA damage promotes telomerase activity SM Hui-Ting Lee, Arindam Bose, Chun-Ying Lee, Patricia L. Opresko Nucleic Acids Research 45 (20), 11752–11765, 2017 | 70 | 2017 |
Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error … P Pande, CK Malik, A Bose, VP Jasti, AK Basu Biochemistry 53 (32), 5323-5331, 2014 | 31 | 2014 |
Position-dependent effect of guanine base damage and mutations on telomeric G-quadruplex and telomerase extension HT Lee, S Sanford, T Paul, J Choe, A Bose, PL Opresko, S Myong Biochemistry 59 (28), 2627-2639, 2020 | 26 | 2020 |
Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitrosamine-derived O2-alkylthymidines in human cells S Weerasooriya, VP Jasti, A Bose, TE Spratt, AK Basu DNA repair 35, 63-70, 2015 | 24 | 2015 |
Elevated levels of mitochondrial CoQ10 induce ROS-mediated apoptosis in pancreatic cancer T Dadali, AR Diers, S Kazerounian, SK Muthuswamy, P Awate, R Ng, ... Scientific Reports 11 (1), 5749, 2021 | 20 | 2021 |
Translesion synthesis of 2′-deoxyguanosine lesions by eukaryotic DNA polymerases AK Basu, P Pande, A Bose Chemical research in toxicology 30 (1), 61-72, 2017 | 19 | 2017 |
DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8–2′-deoxyguanosine adduct of the dietary mutagen IQ in human cells A Bose, P Pande, VP Jasti, AD Millsap, EK Hawkins, CJ Rizzo, AK Basu Nucleic Acids Research 43 (17), 8340-8351, 2015 | 18 | 2015 |
Targeting DNA Repair with Combined Inhibition of NHEJ and MMEJ Induces Synthetic Lethality in TP53-Mutant Cancers J Patterson-Fortin, A Bose, WC Tsai, C Grochala, H Nguyen, J Zhou, ... Cancer research 82 (20), 3815-3829, 2022 | 16 | 2022 |
Comparative Error-Free and Error-Prone Translesion Synthesis of N2-2′-Deoxyguanosine Adducts Formed by Mitomycin C and Its Metabolite, 2,7 … A Bose, C Surugihalli, P Pande, E Champeil, AK Basu Chemical Research in Toxicology 29 (5), 933-939, 2016 | 13 | 2016 |
Translesion Synthesis of the N2-2′-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and … A Bose, AD Millsap, A DeLeon, CJ Rizzo, AK Basu Chemical Research in Toxicology 29 (9), 1549-1559, 2016 | 11 | 2016 |
Pancreatic tumor organoids for modeling in vivo drug response and discovering clinically-actionable biomarkers L Huang, B Bockorny, I Paul, D Akshinthala, O Gandarilla, A Bose, ... bioRxiv, 513267, 2019 | 6 | 2019 |
Combination of M1774 and niraparib can overcome ATR and PARP inhibitor resistance in BRCA1 mutated ovarian cancer models J Hao, A Bose, G Sadatrezaei, DB Martignetti, Y Jiao, AAB da Costa, ... Cancer Research 83 (7_Supplement), 6210-6210, 2023 | 1 | 2023 |
Multiplexed analysis across cancers of diverse origins to unravel spatial interactions within the tumor microenvironment V Agrawal, L Arvidson, MJ Smith, KO White, RA Heil-Chapdelaine, ... Cancer Research 84 (6_Supplement), 5495-5495, 2024 | | 2024 |
Mapping the cancer immune landscape in colorectal adenocarcinoma using multiplexed imaging and AI based analysis V Agrawal, L Arvidson, MJ Smith, KO White, RA Heil-Chapdelaine, ... Cancer Research 84 (6_Supplement), 4914-4914, 2024 | | 2024 |
Spatial architecture of tumor and immune cell lineages in syngeneic mouse tumor tissues A BOSE, L Arvidson, EQ Alonzo, MJ Smith, KO White, ... Cancer Research 84 (6_Supplement), 3803-3803, 2024 | | 2024 |
111 Spatial characterization of the tumor microenvironment with cell DIVE multiplexed imaging and HALO quantitative image analysis AL Ortiz, M Smith, L Arvidson, I Nearchou, D Bowman, A Bose Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
The USP1 inhibitor I-138 kills BRCA1-deficient tumor cells and overcomes PARP inhibitor resistance AABA Da Costa, A Bose, D Martignetti, C Ayala-Zambrano, ... Cancer Research 83 (7_Supplement), 5725-5725, 2023 | | 2023 |