Food, gastrointestinal pH, and models of oral drug absorption AY Abuhelwa, DB Williams, RN Upton, DJR Foster European journal of pharmaceutics and biopharmaceutics 112, 234-248, 2017 | 254 | 2017 |
Methadone N‐demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4 DJR Foster, AA Somogyi, F Bochner British journal of clinical pharmacology 47 (4), 403-412, 1999 | 226 | 1999 |
Steady‐state pharmacokinetics of (R)‐and (S)‐methadone in methadone maintenance patients DJR Foster, AA Somogyi, KR Dyer, JM White, F Bochner British journal of clinical pharmacology 50 (5), 427-440, 2000 | 169 | 2000 |
Steady‐state pharmacokinetics and pharmacodynamics in methadone maintenance patients: comparison of those who do and do not experience withdrawal and concentration‐effect … KR Dyer, DJR Foster, JM White, AA Somogyi, A Menelaou, F Bochner Clinical Pharmacology & Therapeutics 65 (6), 685-694, 1999 | 159 | 1999 |
Pharmacokinetics, efficacy, and tolerability of fentanyl following intranasal versus intravenous administration in adults undergoing third-molar extraction: a randomized … LL Christrup, D Foster, LD Popper, T Troen, R Upton Clinical therapeutics 30 (3), 469-481, 2008 | 151 | 2008 |
CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes MR Hutchinson, A Menelaou, DJR Foster, JK Coller, AA Somogyi British journal of clinical pharmacology 57 (3), 287-297, 2004 | 147 | 2004 |
Pharmacokinetics and pharmacodynamics of intranasal versus intravenous fentanyl in patients with pain after oral surgery D Foster, R Upton, L Christrup, L Popper Annals of Pharmacotherapy 42 (10), 1380-1387, 2008 | 118 | 2008 |
A quantitative review and meta-models of the variability and factors affecting oral drug absorption—part I: gastrointestinal pH AY Abuhelwa, DJR Foster, RN Upton The AAPS journal 18, 1309-1321, 2016 | 98 | 2016 |
Population pharmacokinetic modeling of itraconazole and hydroxyitraconazole for oral SUBA-itraconazole and sporanox capsule formulations in healthy subjects in fed and fasted … AY Abuhelwa, DJR Foster, S Mudge, D Hayes, RN Upton Antimicrobial agents and chemotherapy 59 (9), 5681-5696, 2015 | 96 | 2015 |
The relationship between mood state and plasma methadone concentration in maintenance patients KR Dyer, JM White, DJR Foster, F Bochner, A Menelaou, AA Somogyi Journal of Clinical Psychopharmacology 21 (1), 78-84, 2001 | 92 | 2001 |
Population pharmacokinetics of (R)‐,(S)‐and rac‐methadone in methadone maintenance patients DJR Foster, AA Somogyi, JM White, F Bochner British journal of clinical pharmacology 57 (6), 742-755, 2004 | 87 | 2004 |
Pharmacokinetic‐pharmacodynamic modeling of morphine and oxycodone concentrations and analgesic effect in a multimodal experimental pain model C Staahl, R Upton, DJR Foster, LL Christrup, K Kristensen, SH Hansen, ... The Journal of Clinical Pharmacology 48 (5), 619-631, 2008 | 74 | 2008 |
A quantitative review and meta-models of the variability and factors affecting oral drug absorption—part II: gastrointestinal transit time AY Abuhelwa, DJR Foster, RN Upton The AAPS journal 18, 1322-1333, 2016 | 70 | 2016 |
ABCB1 haplotype and OPRM1 118A > G genotype interaction in methadone maintenance treatment pharmacogenetics DT Barratt, JK Coller, R Hallinan, A Byrne, JM White, DJR Foster, ... Pharmacogenomics and personalized medicine, 53-62, 2012 | 60 | 2012 |
Pharmacokinetic/pharmacodynamic relationships of transdermal buprenorphine and fentanyl in experimental human pain models T Andresen, RN Upton, DJR Foster, LL Christrup, L Arendt‐Nielsen, ... Basic & clinical pharmacology & toxicology 108 (4), 274-284, 2011 | 44 | 2011 |
An introduction to physiologically‐based pharmacokinetic models RN Upton, DJR Foster, AY Abuhelwa Pediatric Anesthesia 26 (11), 1036-1046, 2016 | 43 | 2016 |
The effects of isosteviol against myocardium injury induced by ischaemia–reperfusion in the isolated guinea pig heart D Xu, S Zhang, D Foster JR, J Wang Clinical and Experimental Pharmacology and Physiology 34 (5‐6), 488-493, 2007 | 41 | 2007 |
Stereoselective quantification of methadone and its major oxidative metabolite, 2-ethylidene-1, 5-dimethyl-3, 3-diphenylpyrrolidine, in human urine using high-performance … DJR Foster, AA Somogyi, F Bochner Journal of Chromatography B: Biomedical Sciences and Applications 744 (1 …, 2000 | 41 | 2000 |
Reactivity of gemfibrozil 1-o-beta-acyl glucuronide. Pharmacokinetics of covalently bound gemfibrozil-protein adducts in rats. BC Sallustio, DJ Foster Drug metabolism and disposition 23 (9), 892-899, 1995 | 38 | 1995 |
Pharmacokinetic models of morphine and its metabolites in neonates:: Systematic comparisons of models from the literature, and development of a new meta-model KR Knøsgaard, DJR Foster, M Kreilgaard, E Sverrisdóttir, RN Upton, ... European Journal of Pharmaceutical Sciences 92, 117-130, 2016 | 37 | 2016 |