A quick route to multiple highly potent SARS‐CoV‐2 main protease inhibitors KS Yang, XR Ma, Y Ma, YR Alugubelli, DA Scott, EC Vatansever, ... ChemMedChem 16 (6), 942-948, 2021 | 103 | 2021 |
Epoxides as alkylating reagents for the Catellani reaction HG Cheng, C Wu, H Chen, R Chen, G Qian, Z Geng, Q Wei, Y Xia, ... Angewandte Chemie International Edition 57 (13), 3444-3448, 2018 | 87 | 2018 |
Convergent syntheses of 2, 3-dihydrobenzofurans via a Catellani strategy C Wu, HG Cheng, R Chen, H Chen, ZS Liu, J Zhang, Y Zhang, Y Zhu, ... Organic Chemistry Frontiers 5 (17), 2533-2536, 2018 | 44 | 2018 |
Evaluation of SARS-CoV-2 main protease inhibitors using a novel cell-based assay W Cao, CCD Cho, ZZ Geng, N Shaabani, XR Ma, EC Vatansever, ... ACS central science 8 (2), 192-204, 2022 | 35 | 2022 |
A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals Y Ma, KS Yang, ZZ Geng, YR Alugubelli, N Shaabani, EC Vatansever, ... European Journal of Medicinal Chemistry 240, 114570, 2022 | 31 | 2022 |
A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals YR Alugubelli, ZZ Geng, KS Yang, N Shaabani, K Khatua, XR Ma, ... European Journal of Medicinal Chemistry 240, 114596, 2022 | 26 | 2022 |
A reversible chemogenetic switch for chimeric antigen receptor T cells W Cao, ZZ Geng, N Wang, Q Pan, S Guo, S Xu, J Zhou, WR Liu Angewandte Chemie 134 (10), e202109550, 2022 | 11 | 2022 |
Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease KS Yang, STA Kuo, LR Blankenship, ZZ Geng, SG Li, DH Russell, X Yan, ... Current Research in Chemical Biology 2, 100025, 2022 | 9 | 2022 |
A systematic survey of reversibly covalent dipeptidyl inhibitors of the SARS-CoV-2 main protease ZZ Geng, S Atla, N Shaabani, V Vulupala, KS Yang, YR Alugubelli, ... Journal of Medicinal Chemistry 66 (16), 11040-11055, 2023 | 8 | 2023 |
Cellular activities of SARS-CoV-2 main protease inhibitors reveal their unique characteristics W Cao, CCD Cho, ZZ Geng, XR Ma, R Allen, N Shaabani, EC Vatansever, ... bioRxiv, 2021.06. 08.447613, 2021 | 7 | 2021 |
A designed, highly efficient pyrrolysyl-tRNA synthetase mutant binds o-chlorophenylalanine using two halogen bonds EC Vatansever, KS Yang, ZZ Geng, Y Qiao, P Li, S Xu, WR Liu Journal of molecular biology 434 (8), 167534, 2022 | 6 | 2022 |
The N-Terminal Carbamate is Key to High Cellular and Antiviral Potency for Boceprevir-Based SARS-CoV-2 Main Protease Inhibitors YR Alugubelli, ZZ Geng, KS Yang, N Shaabani, K Khatua, XR Ma, ... BioRxiv, 2021.12. 18.473330, 2021 | 5 | 2021 |
The P3 O-Tert-Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors Y Ma, KS Yang, ZZ Geng, YR Alugubelli, N Shaabani, EC Vatansever, ... bioRxiv, 2021.12. 18.473326, 2021 | 4 | 2021 |
An amber-encoding helper phage for more efficient phage display of noncanonical amino acids JT Hampton, CCD Cho, DD Coleman, ZZ Geng, PHC Chen, GK Dubey, ... Nucleic Acids Research 51 (13), 6566-6577, 2023 | 2 | 2023 |
Leveraging a Phage-Encoded Noncanonical Amino Acid: A Novel Pathway to Potent and Selective Epigenetic Reader Protein Inhibitors PHC Chen, XS Guo, HE Zhang, GK Dubey, ZZ Geng, CA Fierke, S Xu, ... ACS Central Science, 2024 | 1 | 2024 |
An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease K Khatua, YR Alugubelli, KS Yang, VR Vulupala, LR Blankenship, ... bioRxiv, 2023.04. 11.536467, 2023 | 1 | 2023 |
Azapeptides with unique covalent warheads as SARS-CoV-2 main protease inhibitors K Khatua, YR Alugubelli, KS Yang, VR Vulupala, LR Blankenship, ... Antiviral Research 225, 105874, 2024 | | 2024 |
Phage-Assisted, Active Site-Directed Ligand Evolution with a Genetically Encoded Nε-Butyryl-L-Lysine to Identify a Cellularly Potent and Selective Inhibitor for … PHC Chen, XS Guo, HE Zhang, ZZ Geng, GK Dubey, CA Fierke, S Xu, ... bioRxiv, 2023.01. 08.523168, 2023 | | 2023 |
A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease (preprint) ZZ Geng, S Atla, N Shaabani, VR Vulupara, KS Yang, YR Alugubelli, ... | | 2023 |
Titelbild: A Reversible Chemogenetic Switch for Chimeric Antigen Receptor T Cells (Angew. Chem. 10/2022) W Cao, ZZ Geng, N Wang, Q Pan, S Guo, S Xu, J Zhou, WR Liu Angewandte Chemie 134 (10), e202201860, 2022 | | 2022 |