| Kv2. 1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion DA Jacobson, A Kuznetsov, JP Lopez, S Kash, CE Ämmälä, LH Philipson Cell metabolism 6 (3), 229-235, 2007 | 195 | 2007 |
| ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload RA Egnatchik, AK Leamy, DA Jacobson, M Shiota, JD Young Molecular metabolism 3 (5), 544-553, 2014 | 180 | 2014 |
| Cystic fibrosis–related diabetes is caused by islet loss and inflammation NJ Hart, R Aramandla, G Poffenberger, C Fayolle, AH Thames, A Bautista, ... JCI insight 3 (8), 2018 | 165 | 2018 |
| Extranuclear actions of the androgen receptor enhance glucose-stimulated insulin secretion in the male G Navarro, W Xu, DA Jacobson, B Wicksteed, C Allard, G Zhang, ... Cell metabolism 23 (5), 837-851, 2016 | 159 | 2016 |
| Duplication of ATR inhibits MyoD, induces aneuploidy and eliminates radiation-induced G1 arrest L Smith, SJ Liu, L Goodrich, D Jacobson, C Degnin, N Bentley, A Carr, ... Nature genetics 19 (1), 39-46, 1998 | 112 | 1998 |
| Synaptotagmin 4 regulates pancreatic β cell maturation by modulating the Ca2+ sensitivity of insulin secretion vesicles C Huang, EM Walker, PK Dadi, R Hu, Y Xu, W Zhang, T Sanavia, J Mun, ... Developmental cell 45 (3), 347-361. e5, 2018 | 93 | 2018 |
| Ion channels and regulation of insulin secretion in human β-cells: a computational systems analysis LE Fridlyand, DA Jacobson, LH Philipson Islets 5 (1), 1-15, 2013 | 87 | 2013 |
| β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions L Zhu, J Almaça, PK Dadi, H Hong, W Sakamoto, M Rossi, RJ Lee, ... Nature communications 8 (1), 14295, 2017 | 86 | 2017 |
| Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2β in pancreatic β-cells and in iPLA2β-null mice S Bao, DA Jacobson, M Wohltmann, A Bohrer, W Jin, LH Philipson, J Turk American Journal of Physiology-Endocrinology and Metabolism 294 (2), E217-E229, 2008 | 86 | 2008 |
| The Physiological Effects of Deleting the Mouse Slc30a8 Gene Encoding Zinc Transporter-8 Are Influenced by Gender and Genetic Background LD Pound, SA Sarkar, A Ustione, PK Dadi, MK Shadoan, CE Lee, ... PloS one 7 (7), e40972, 2012 | 81 | 2012 |
| G6PC2: a negative regulator of basal glucose-stimulated insulin secretion LD Pound, JK Oeser, TP O’Brien, Y Wang, CJ Faulman, PK Dadi, ... Diabetes 62 (5), 1547-1556, 2013 | 77 | 2013 |
| Calcium‐activated and voltage‐gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses DA Jacobson, F Mendez, M Thompson, J Torres, O Cochet, LH Philipson The Journal of physiology 588 (18), 3525-3537, 2010 | 77 | 2010 |
| The granular chloride channel ClC-3 is permissive for insulin secretion LV Deriy, EA Gomez, DA Jacobson, XQ Wang, JA Hopson, XY Liu, ... Cell metabolism 10 (4), 316-323, 2009 | 77 | 2009 |
| Chronic β-cell depolarization impairs β-cell identity by disrupting a network of Ca2+-regulated genes JS Stancill, JP Cartailler, HW Clayton, JT O’Connor, MT Dickerson, ... Diabetes 66 (8), 2175-2187, 2017 | 76 | 2017 |
| β-Cell–specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion KA Kaihara, LM Dickson, DA Jacobson, N Tamarina, MW Roe, ... Diabetes 62 (5), 1527-1536, 2013 | 75 | 2013 |
| Inhibition of pancreatic β-cell Ca2+/calmodulin-dependent protein kinase II reduces glucose-stimulated calcium influx and insulin secretion, impairing glucose tolerance PK Dadi, NC Vierra, A Ustione, DW Piston, RJ Colbran, DA Jacobson Journal of Biological Chemistry 289 (18), 12435-12445, 2014 | 69 | 2014 |
| Type 2 diabetes–associated K+ channel TALK-1 modulates β-cell electrical excitability, second-phase insulin secretion, and glucose homeostasis NC Vierra, PK Dadi, I Jeong, M Dickerson, DR Powell, DA Jacobson Diabetes 64 (11), 3818-3828, 2015 | 67 | 2015 |
| Determinants contributing to estrogen-regulated expression of SK3 D Jacobson, D Pribnow, PS Herson, J Maylie, JP Adelman Biochemical and biophysical research communications 303 (2), 660-668, 2003 | 66 | 2003 |
| Glucocorticoids reprogram β-cell signaling to preserve insulin secretion NHF Fine, CL Doig, YS Elhassan, NC Vierra, P Marchetti, M Bugliani, ... Diabetes 67 (2), 278-290, 2018 | 65 | 2018 |
| Modulation of the pancreatic islet β-cell-delayed rectifier potassium channel Kv2. 1 by the polyunsaturated fatty acid arachidonate DA Jacobson, CR Weber, S Bao, J Turk, LH Philipson Journal of Biological Chemistry 282 (10), 7442-7449, 2007 | 65 | 2007 |
