| Structural insights into RAMP modification of secretin family G protein-coupled receptors: implications for drug development JK Archbold, JU Flanagan, HA Watkins, JJ Gingell, DL Hay Trends in pharmacological sciences 32 (10), 591-600, 2011 | 109 | 2011 |
| Calcitonin and calcitonin receptor‐like receptors: common themes with family B GPCRs? J Barwell, JJ Gingell, HA Watkins, JK Archbold, DR Poyner, DL Hay British journal of pharmacology 166 (1), 51-65, 2012 | 95 | 2012 |
| Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors C Weston, I Winfield, M Harris, R Hodgson, A Shah, SJ Dowell, ... Journal of Biological Chemistry 291 (42), 21925-21944, 2016 | 89 | 2016 |
| Structure–activity relationships for α‐calcitonin gene‐related peptide HA Watkins, DL Rathbone, J Barwell, DL Hay, DR Poyner British Journal of Pharmacology 170 (7), 1308-1322, 2013 | 74 | 2013 |
| The structure of secretin family GPCR peptide ligands: implications for receptor pharmacology and drug development HA Watkins, M Au, DL Hay Drug discovery today 17 (17-18), 1006-1014, 2012 | 66 | 2012 |
| An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology J J Gingell, J Simms, J Barwell, DR Poyner, HA Watkins, AA Pioszak, ... Cell discovery 2 (1), 1-14, 2016 | 64 | 2016 |
| Receptor activity‐modifying protein‐dependent impairment of calcitonin receptor splice variant Δ(1–47)hCT(a) function T Qi, M Dong, HA Watkins, D Wootten, LJ Miller, DL Hay British journal of pharmacology 168 (3), 644-657, 2013 | 55 | 2013 |
| Receptor activity‐modifying protein‐dependent effects of mutations in the calcitonin receptor‐like receptor: implications for adrenomedullin and calcitonin gene‐related peptide … HA Watkins, CS Walker, KN Ly, RJ Bailey, J Barwell, DR Poyner, DL Hay British journal of pharmacology 171 (3), 772-788, 2014 | 47 | 2014 |
| Receptor activity-modifying proteins 2 and 3 generate adrenomedullin receptor subtypes with distinct molecular properties HA Watkins, M Chakravarthy, RS Abhayawardana, JJ Gingell, M Garelja, ... Journal of Biological Chemistry 291 (22), 11657-11675, 2016 | 46 | 2016 |
| Structural and Functional Characterization of an RNase HI Domain from the Bifunctional Protein Rv2228c from Mycobacterium tuberculosis HA Watkins, EN Baker Journal of bacteriology 192 (11), 2878-2886, 2010 | 40 | 2010 |
| Identification of key residues involved in adrenomedullin binding to the AM1 receptor HA Watkins, M Au, R Bobby, JK Archbold, N Abdul‐Manan, JM Moore, ... British journal of pharmacology 169 (1), 143-155, 2013 | 37 | 2013 |
| The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach MJ Woolley, HA Watkins, B Taddese, ZG Karakullukcu, J Barwell, ... Journal of The Royal Society Interface 10 (88), 20130589, 2013 | 36 | 2013 |
| Molecular mechanisms of class B GPCR activation: insights from adrenomedullin receptors ML Garelja, M Au, MA Brimble, JJ Gingell, ER Hendrikse, A Lovell, ... ACS pharmacology & translational science 3 (2), 246-262, 2020 | 33 | 2020 |
| Structural and Functional Analysis of Rv3214 from Mycobacterium tuberculosis, a Protein with Conflicting Functional Annotations, Leads to Its Characterization as a … HA Watkins, EN Baker Journal of bacteriology 188 (10), 3589-3599, 2006 | 30 | 2006 |
| Receptor activity modifying proteins have limited effects on the Class BG protein-coupled receptor calcitonin receptor-like receptor stalk ML Garelja, CA Walker, A Siow, SH Yang, PWR Harris, MA Brimble, ... Biochemistry 57 (8), 1410-1422, 2018 | 10 | 2018 |
| Cloning, expression, purification and preliminary crystallographic analysis of the RNase HI domain of the Mycobacterium tuberculosis protein Rv2228c as a maltose-binding … HA Watkins, EN Baker Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008 | 10 | 2008 |
| Pharmacological characterization and investigation of N-terminal loop amino acids of adrenomedullin 2 that are important for receptor activation H Musa, ER Hendrikse, MA Brimble, ML Garelja, HA Watkins, PWR Harris, ... Biochemistry 58 (32), 3468-3474, 2019 | 9 | 2019 |
| Cloning, expression, purification and preliminary crystallographic data for Rv3214 (EntD), a predicted cofactor-dependent phosphoglycerate mutase from Mycobacterium tuberculosis HA Watkins, M Yu, EN Baker Acta Crystallographica Section F: Structural Biology and Crystallization …, 2005 | 5 | 2005 |
| Michael Garelja1, Meenakshi Pardamwar3, James MWR McElhinney3, Alex Lathbridge3, Arran Constantine3, Paul WR Harris2, 4, Tsz-Ying Yuen2, 4, Margaret A. Brimble2, 4, James … HA Watkins, M Chakravarthy, RS Abhayawardana, JJ Gingell | | 2016 |
| The role of ECL2 in CGRP receptor activation: a combined KJ Smith, DL Hay, DR Poyner, CA Reynolds, AC Conner, MJ Woolley, ... Journal of The Royal Society Interface 10 (88), 20130589, 2013 | | 2013 |
Debbie L HayDepartment of Pharmacology & Toxicology, University of Otago and School of Biological SciencesVerified email at otago.ac.nz
