| Kinetic characterization of 100 glycoside hydrolase mutants enables the discovery of structural features correlated with kinetic constants DA Carlin, RW Caster, X Wang, SA Betzenderfer, CX Chen, VM Duong, ... PLoS One 11 (1), e0147596, 2016 | 53 | 2016 |
| Thermal stability and kinetic constants for 129 variants of a family 1 glycoside hydrolase reveal that enzyme activity and stability can be separately designed DA Carlin, S Hapig-Ward, BW Chan, N Damrau, M Riley, RW Caster, ... PLoS One 12 (5), e0176255, 2017 | 25 | 2017 |
| Elucidating substrate promiscuity within the FabI enzyme family GS Freund, TE O’Brien, L Vinson, DA Carlin, A Yao, WS Mak, ... ACS Chemical Biology 12 (9), 2465-2473, 2017 | 19 | 2017 |
| Biocatalytic conversion of ethylene to ethylene oxide using an engineered toluene monooxygenase DA Carlin, SJ Bertolani, JB Siegel Chemical communications 51 (12), 2283-2285, 2015 | 14 | 2015 |
| Computational design of ligand binding proteins BL Stoddard Humana Press, 2016 | 12 | 2016 |
| Systematic Functional Analysis of Active-Site Residues in l-Threonine Dehydrogenase from Thermoplasma volcanium M Desjardins, WS Mak, TE O’Brien, DA Carlin, DJ Tantillo, JB Siegel ACS omega 2 (7), 3308-3314, 2017 | 8 | 2017 |
| The live biotherapeutic SYNB1353 decreases plasma methionine via directed degradation in animal models and healthy volunteers M Perreault, J Means, E Gerson, M James, S Cotton, CG Bergeron, ... Cell Host & Microbe, 2024 | 4 | 2024 |
| Bacteria engineered for conversion of ethylene to ethanol S Atsumi, MD Toney, GM Rodriguez, Y Tashiro, JB Siegel, DA CARLIN, ... US Patent 10,184,138, 2019 | 3 | 2019 |
| Biosynthesis of cannabinoids and cannabinoid precursors KC Anderson, DA Carlin, N Flores, K Forrest, RL Prathuri, G Rodriguez, ... US Patent App. 17/636,351, 2022 | 1 | 2022 |
| Biosynthesis of cannabinoids and cannabinoid precursors KC Anderson, E Brevnova, DA Carlin, B Carvalho, N Flores, K Forrest, ... US Patent 11,274,320, 2022 | 1 | 2022 |
| Development of an engineered probiotic for the treatment of branched chain amino acid related metabolic diseases N Li, A Tucker, JR Gao, L Renaud, M James, M Castillo, S Galvan, R Jain, ... | 1 | 2021 |
| Organophosphorus nerve agent hydrolyzing enzymes D Borhani, DA Carlin, A Tucker US Patent App. 18/283,688, 2024 | | 2024 |
| Biosynthesis of cannabinoids and cannabinoid precursors DA Carlin, B Carvalho, N Flores, K Forrest, G Rodriguez, NW Schmidt, ... US Patent App. 18/031,522, 2024 | | 2024 |
| Recombinant bacteria engineered to treat diseases associated with methionine metabolism and methods of use thereof DA Carlin, VM Isabella, J McMurry, TC Moore III, M Perreault, N Schmidt, ... US Patent App. 18/524,651, 2024 | | 2024 |
| BIOSYNTHESIS OF ENZYMES FOR USE IN TREATING MAPLE SYRUP DISEASE (MSUD) R Jain, R Putman, K Zimmerman, P Boyle, DA Carlin, L Stone, AC Tucker | | 2024 |
| Recombinant bacteria engineered to treat diseases associated with methionine metabolism and methods of use thereof DA Carlin, VM Isabella, J McMurry, TC Moore III, M Perreault, N Schmidt, ... US Patent 11,859,189, 2024 | | 2024 |
| OPTIMIZED BACTERIA MODIFIED TO TREAT DISORDERS INVOLVING THE CATABOLISM OF LEUCINE, ISOLEUCINE AND/OR VALINE N Li, J GAO, PJR MORRISON, CG BERGERON, PM BOYLE, LK STONE, ... | | 2023 |
| Biosynthesis of cannabinoids and cannabinoid precursors KC Anderson, J lan Boucher, E Brevnova, DA Carlin, B Carvalho, ... US Patent App. 17/914,060, 2023 | | 2023 |
| Optimized bacteria engineered to treat disorders involving the catabolism of leucine, isoleucine, and/or valine N Li, J Gao, PJR Morrison, CG Bergeron, DA Carlin, LK Stone, AC Tucker, ... US Patent App. 17/621,121, 2022 | | 2022 |
| Biosynthesis of cannabinoids and cannabinoid precursors KC Anderson, E Brevnova, DA Carlin, B Carvalho, N Flores, K Forrest, ... US Patent App. 17/690,446, 2022 | | 2022 |
